ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection L Zhou, Z Xu, GM Castiglione, US Soiberman, CG Eberhart, EJ Duh The ocular surface 18 (4), 537-544, 2020 | 370 | 2020 |
Microglia polarization with M1/M2 phenotype changes in rd1 mouse model of retinal degeneration T Zhou, Z Huang, X Sun, X Zhu, L Zhou, M Li, B Cheng, X Liu, C He Frontiers in Neuroanatomy 11, 77, 2017 | 195 | 2017 |
NGF increases VEGF expression and promotes cell proliferation via ERK1/2 and AKT signaling in Müller cells J Wang, C He, T Zhou, Z Huang, L Zhou, X Liu Molecular Vision 22, 254, 2016 | 66 | 2016 |
Expression of the SARS-CoV-2 receptor ACE2 in human retina and diabetes—implications for retinopathy L Zhou, Z Xu, J Guerra, AZ Rosenberg, P Fenaroli, CG Eberhart, EJ Duh Investigative Ophthalmology & Visual Science 62 (7), 6-6, 2021 | 42 | 2021 |
Inhibition of the Keap1-Nrf2 protein-protein interaction protects retinal cells and ameliorates retinal ischemia-reperfusion injury Q Hui, M Karlstetter, Z Xu, J Yang, L Zhou, HM Eilken, C Terjung, H Cho, ... Free Radical Biology and Medicine 146, 181-188, 2020 | 37 | 2020 |
Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds GM Castiglione, Z Xu, L Zhou, EJ Duh Nature communications 11 (1), 2476, 2020 | 34 | 2020 |
iPSC-derived endothelial cell response to hypoxia via SDF1a/CXCR4 axis facilitates incorporation to revascularize ischemic retina H Cho, BL Macklin, YY Lin, L Zhou, MJ Lai, G Lee, S Gerecht, EJ Duh Jci Insight 5 (6), 2020 | 32 | 2020 |
Imatinib ameliorated retinal neovascularization by suppressing PDGFR-α and PDGFR-β L Zhou, X Sun, Z Huang, T Zhou, X Zhu, Y Liu, J Wang, B Cheng, M Li, ... Cellular Physiology and Biochemistry 48 (1), 263-273, 2018 | 26 | 2018 |
Dendrimer‐triamcinolone acetonide reduces neuroinflammation, pathological angiogenesis, and neuroretinal dysfunction in ischemic retinopathy H Cho, SP Kambhampati, MJ Lai, L Zhou, G Lee, Y Xie, Q Hui, ... Advanced therapeutics 4 (2), 2000181, 2021 | 16 | 2021 |
Myeloid cell modulation by a GLP-1 receptor agonist regulates retinal angiogenesis in ischemic retinopathy L Zhou, Z Xu, Y Oh, R Gamuyao, G Lee, Y Xie, H Cho, S Lee, EJ Duh JCI insight 6 (23), 2021 | 14 | 2021 |
TLR2/4 deficiency prevents oxygen-induced vascular degeneration and promotes revascularization by downregulating IL-17 in the retina C He, P Lai, J Wang, T Zhou, Z Huang, L Zhou, X Liu Scientific Reports 6 (1), 27739, 2016 | 13 | 2016 |
Evolutionary pathways to SARS-CoV-2 resistance are opened and closed by epistasis acting on ACE2 GM Castiglione, L Zhou, Z Xu, Z Neiman, CF Hung, EJ Duh PLoS biology 19 (12), e3001510, 2021 | 9 | 2021 |
Nonhuman Primate Eyes Display Variable Growth and Aging Rates in Alignment With Human Eyes Y Xue, Y Cao, S Fan, M Xu, Z Yang, L Zhou, L Shi, L Ou, Y Li, W Qing, ... Investigative ophthalmology & visual science 64 (11), 23-23, 2023 | 2 | 2023 |
The ancient cardioprotective mechanisms of ACE2 bestow SARS-CoV-2 with a wide host range GM Castiglione, L Zhou, Z Xu, Z Neiman, CF Hung, EJ Duh bioRxiv, 2021.01. 03.425115, 2021 | 2 | 2021 |
Use of sgc activators for the treatment of ophthalmologic diseases WE Schubert, K Nassar, P Sandner, C Terjung, E Duh, CHO Hongkwan, ... US Patent App. 18/134,875, 2023 | | 2023 |
Use of sgc activators for the treatment of ophthalmologic diseases WE Schubert, K Nassar, P Sandner, C Terjung, E Duh, CHO Hongkwan, ... US Patent App. 17/667,418, 2022 | | 2022 |
Glp-1r agonist and methods of treatment E Duh, Z Xu, L Zhou, S Lee, Y Oh US Patent App. 17/194,177, 2021 | | 2021 |
Retinal vascular effects of novel soluble guanylate cyclase activator (sGCa) runcaciguat K Nassar, W Schubert, Z Xu, C Terjung, L Zhou, J Guerra, K Rheindorf, ... Investigative Ophthalmology & Visual Science 62 (8), 3002-3002, 2021 | | 2021 |
Neuroprotective and Anti-Inflammatory Effects of a Novel Soluble Guanylate Cyclase Activator Runcaciguat in Ischemic Retinal Disease Animal Models EJ Duh, W Schubert, Z Xu, C Terjung, H Cho, L Zhou, L Wu, J Guerra, ... Investigative Ophthalmology & Visual Science 62 (8), 1078-1078, 2021 | | 2021 |
Targeted Therapy: Dendrimer‐Triamcinolone Acetonide Reduces Neuroinflammation, Pathological Angiogenesis, and Neuroretinal Dysfunction in Ischemic Retinopathy (Adv. Therap. 2/2021) H Cho, SP Kambhampati, MJ Lai, L Zhou, G Lee, Y Xie, Q Hui, ... Advanced Therapeutics 4 (2), 2170003, 2021 | | 2021 |