The molecular mechanism of nuclear transport revealed by atomic-scale measurements LE Hough, K Dutta, S Sparks, DB Temel, A Kamal, J Tetenbaum-Novatt, ... Elife 4, e10027, 2015 | 158 | 2015 |
Mechanistic studies of peptide self-assembly: transient α-helices to stable β-sheets G Liu, A Prabhakar, D Aucoin, M Simon, S Sparks, KJ Robbins, A Sheen, ... Journal of the American Chemical Society 132 (51), 18223-18232, 2010 | 94 | 2010 |
Curcumin modulates the self-assembly of the islet amyloid polypeptide by disassembling α-helix S Sparks, G Liu, KJ Robbins, ND Lazo Biochemical and biophysical research communications 422 (4), 551-555, 2012 | 79 | 2012 |
Thermodynamic characterization of the multivalent interactions underlying rapid and selective translocation through the nuclear pore complex R Hayama, S Sparks, LM Hecht, K Dutta, JM Karp, CM Cabana, MP Rout, ... Journal of Biological Chemistry 293 (12), 4555-4563, 2018 | 57 | 2018 |
Controlling lipid micelle stability using oligonucleotide headgroups SE Wilner, SE Sparks, D Cowburn, ME Girvin, M Levy Journal of the American Chemical Society 137 (6), 2171-2174, 2015 | 27 | 2015 |
Deciphering the “fuzzy” interaction of FG nucleoporins and transport factors using small-angle neutron scattering S Sparks, DB Temel, MP Rout, D Cowburn Structure 26 (3), 477-484. e4, 2018 | 21 | 2018 |
Effects of FGFR2 kinase activation loop dynamics on catalytic activity JM Karp, S Sparks, D Cowburn PLoS computational biology 13 (2), e1005360, 2017 | 14 | 2017 |
Design of a systemic small molecule clinical STING agonist using physics-based simulations and artificial intelligence BK Allen, MM Kulkarni, B Chamberlain, T Dwight, C Koh, R Samant, ... Biorxiv, 2022.05. 23.493001, 2022 | 10 | 2022 |
Analysis of multivalent IDP interactions: stoichiometry, affinity, and local concentration effect measurements S Sparks, R Hayama, MP Rout, D Cowburn Intrinsically Disordered Proteins: Methods and Protocols, 463-475, 2020 | 2 | 2020 |
Abstract LB-A20: True small molecule STING agonist generates systemic and potent anti-tumor immunity required for effective cancer immunotherapy MM Kulkarni, T Dwight, K Marino, BK Allen, M Taimi, C Bastos, S Lai, ... Molecular Cancer Therapeutics 18 (12_Supplement), LB-A20-LB-A20, 2019 | | 2019 |
True small molecule STING agonist generates systemic and potent anti-tumor immunity required for effective cancer immunotherapy MM Kulkarni, T Dwight, K Marino, BK Allen, M Taimi, C Bastos, S Lai, ... MOLECULAR CANCER THERAPEUTICS 18 (12), 2019 | | 2019 |
Tackling challenging targets in innate immune pathways with integrated biophysics and simulation H Soutter, I Kolossvary, K Marino, S Sparks, H Xu, W Sherman ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
Deciphering the'fuzzy'interaction of FG nucleoporins and transport factors using SANS D Cowburn, S Sparks, DB Temel, MP Rout Acta Crystallographica Section A: Foundations and Advances 75, a395-a395, 2019 | | 2019 |
Thermodynamics of The Interactions of FG‐Nucleoporins and Transport Factors S Sparks, R Hayama, MP Rout, D Cowburn The FASEB Journal 32, lb58-lb58, 2018 | | 2018 |
The [alpha]-helix in Maturing Assemblies of the Islet Amyloid Polypeptide is Susceptible to Unfolding by Biphenols S Sparks Clark University, 2011 | | 2011 |