Robert P Sheehan
Robert P Sheehan
Harvard Medical School
Verified email at hms.harvard.edu - Homepage
Title
Cited by
Cited by
Year
BioNetGen 2.2: advances in rule-based modeling
LA Harris, JS Hogg, JJ Tapia, JAP Sekar, S Gupta, I Korsunsky, A Arora, ...
Bioinformatics 32 (21), 3366-3368, 2016
1162016
Cutting edge: differential regulation of PTEN by TCR, Akt, and FoxO1 controls CD4+ T cell fate decisions
WF Hawse, RP Sheehan, N Miskov-Zivanov, AV Menk, LP Kane, ...
The Journal of Immunology 194 (10), 4615-4619, 2015
322015
Adaptation of human iPSC-derived cardiomyocytes to tyrosine kinase inhibitors reduces acute cardiotoxicity via metabolic reprogramming
H Wang, RP Sheehan, AC Palmer, RA Everley, SA Boswell, N Ron-Harel, ...
Cell systems 8 (5), 412-426. e7, 2019
132019
A neutrophil phenotype model for extracorporeal treatment of sepsis
AD Malkin, RP Sheehan, S Mathew, WJ Federspiel, H Redl, G Clermont
PLoS Comput Biol 11 (10), e1004314, 2015
102015
Neutrophil phenotype model for extracorporeal treatment of sepsis
A Malkin, R Sheehan, S Mathew, H Redl, G Clermont
Critical Care 18 (1), 1-182, 2014
32014
Drug adaptation influences cardiotoxicity caused by tyrosine kinase inhibitors in iPSC-derived human cardiomyocytes
H Wang, RP Sheehan, AC Palmer, RA Everley, SA Boswell, N Ron-Harel, ...
bioRxiv, 365841, 2018
2018
Unraveling how T cell antigen receptor signaling strength determines T cell differentiation using a combined experimental and computational approach
J Faeder, RP Sheehan, WF Hawse, MJ Gable, REC Lee, PA Morel
The Journal of Immunology 198 (1 Supplement), 150.19-150.19, 2017
2017
Closing the loop: A combined computational modeling and experimental approach provides novel insights into immune cell signaling systems and their global effects.
R Sheehan
University of Pittsburgh, 2016
2016
Evaluation of Galectin-9 blocking mono-clonal antibodies as novel immune-checkpoint inhibitors via the targeting of regulatory T cells in cancer
PA Morel, WF Hawse, RP Sheehan, WC Boggess, JR Faeder
EUROPEAN JOURNAL OF IMMUNOLOGY 46, 14-15, 2016
2016
TCR signal strength regulates Akt substrate specificity to induce alternate Th and Treg differentiation programs
PA Morel, WF Hawse, RP Sheehan, WC Boggess, JR Faeder
The Journal of Immunology 196 (1 Supplement), 128.10-128.10, 2016
2016
Systems biology approach to determine critical T cell receptor signaling events for the induction of regulatory T cells (LYM8P. 639)
R Sheehan, W Hawse, P Morel, J Faeder
The Journal of Immunology 194 (1 Supplement), 201.15-201.15, 2015
2015
A computational model for mechanistic investigation of negative feedback in interleukin-17 receptor signaling (CCR3P. 201)
R Sheehan, A Garg, S Gaffen, J Faeder
The Journal of Immunology 194 (1 Supplement), 49.2-49.2, 2015
2015
A computational model for mechanistic investigation of negative feedback in Inerleukin-17 receptor signaling (CCR6P. 274)
R Sheehan, A Garg, S Gaffen, J Faeder
The Journal of Immunology 192 (1 Supplement), 182.6-182.6, 2014
2014
Computational model for mechanistic investigation of negative feedback in Interleukin-17 receptor signaling
RP Sheehan, A Garg, SL Gaffen, JR Faeder
CYTOKINE 63 (3), 299-299, 2013
2013
236: Computational model for mechanistic investigation of negative feedback in Interleukin-17 receptor signaling
RP Sheehan, A Garg, SL Gaffen, JR Faeder
Cytokine 63 (3), 299, 2013
2013
Heterochromatin Is Retained During Lens Fiber Cell Differentiation
MK Duncan, RP Sheehan
Investigative Ophthalmology & Visual Science 52 (14), 2779-2779, 2011
2011
Heterochromatin is retained during lens fiber cell differentiation
RP Sheehan, MK Duncan
The FASEB Journal 25 (1_supplement), 896.7-896.7, 2011
2011
The Effects of Histone Modifications on Lens Cell Denucleation
RP Sheehan, M Duncan
The FASEB Journal 24 (1_supplement), 460.3-460.3, 2010
2010
Using the automated building of computational models to understand cardiotoxic drug responses
RP Sheehan, H Wang, BM Gyori, JA Bachman, PK Sorger
Novel positive feedback loop sets antigen dose-dependent threshold for T cell differentiation
RP Sheehan, WF Hawse, REC Lee, PA Morel, JR Faeder
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Articles 1–20