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Timothy A Simeone
Timothy A Simeone
Creighton University School of Medicine
Verifierad e-postadress på creighton.edu
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Ketone bodies are protective against oxidative stress in neocortical neurons
DY Kim, LM Davis, PG Sullivan, M Maalouf, TA Simeone, J Brederode, ...
Journal of neurochemistry 101 (5), 1316-1326, 2007
1902007
Ketone bodies mediate antiseizure effects through mitochondrial permeability transition
DY Kim, KA Simeone, TA Simeone, JD Pandya, JC Wilke, Y Ahn, ...
Annals of neurology 78 (1), 77-87, 2015
1372015
Molecular biology and ontogeny of glutamate receptors in the mammalian central nervous system
TA Simeone, RM Sanchez, JM Rho
Journal of child neurology 19 (5), 343-360, 2004
1282004
Mechanisms of seizure-induced ‘transcriptional channelopathy’of hyperpolarization-activated cyclic nucleotide gated (HCN) channels
C Richichi, AL Brewster, RA Bender, TA Simeone, Q Zha, HZ Yin, ...
Neurobiology of disease 29 (2), 297-305, 2008
962008
Modulation by topiramate of AMPA and kainate mediated calcium influx in cultured cerebral cortical, hippocampal and cerebellar neurons
CF Poulsen, TA Simeone, TE Maar, V Smith-Swintosky, HS White, ...
Neurochemical research 29 (1), 275-282, 2004
842004
Do ketone bodies mediate the anti-seizure effects of the ketogenic diet?
TA Simeone, KA Simeone, CE Stafstrom, JM Rho
Neuropharmacology 133, 233-241, 2018
802018
Molecular biology and ontogeny of γ-aminobutyric acid (GABA) receptors in the mammalian central nervous system
TA Simeone, SD Donevan, JM Rho
Journal of child neurology 18 (1), 39-48, 2003
752003
Hypothalamic hamartoma: basic mechanisms of intrinsic epileptogenesis
KA Fenoglio, J Wu, TA Simeone, SW Coons, H Rekate, JM Rho, ...
Seminars in Pediatric Neurology 14 (2), 51-59, 2007
712007
Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy
TA Simeone, SA Matthews, KK Samson, KA Simeone
Experimental neurology 287, 54-64, 2017
612017
Subunit selectivity of topiramate modulation of heteromeric GABAA receptors
TA Simeone, KS Wilcox, HS White
Neuropharmacology 50 (7), 845-857, 2006
602006
Ketone bodies as anti-seizure agents
TA Simeone, KA Simeone, JM Rho
Neurochemical research 42 (7), 2011-2018, 2017
562017
Ketogenic diet treatment increases longevity in Kcna1‐null mice, a model of sudden unexpected death in epilepsy
KA Simeone, SA Matthews, JM Rho, TA Simeone
Epilepsia 57 (8), e178-e182, 2016
542016
Targeting deficiencies in mitochondrial respiratory complex I and functional uncoupling exerts anti-seizure effects in a genetic model of temporal lobe epilepsy and in a model …
KA Simeone, SA Matthews, KK Samson, TA Simeone
Experimental neurology 251, 84-90, 2014
532014
Loss of the Kv1. 1 potassium channel promotes pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices
TA Simeone, KA Simeone, KK Samson, JM Rho
Neurobiology of disease 54, 68-81, 2013
532013
GABAA receptor‐mediated activation of L‐type calcium channels induces neuronal excitation in surgically resected human hypothalamic hamartomas
DY Kim, KA Fenoglio, TA Simeone, SW Coons, J Wu, Y Chang, ...
Epilepsia 49 (5), 861-871, 2008
502008
Orexin Receptor Antagonism Improves Sleep and Reduces Seizures in Kcna1-null Mice
HM Roundtree, TA Simeone, C Johnson, SA Matthews, KK Samson, ...
Sleep 39 (2), 357-368, 2016
452016
Single channel properties of hyperpolarization‐activated cation currents in acutely dissociated rat hippocampal neurones
TA Simeone, JM Rho, TZ Baram
The Journal of physiology 568 (2), 371-380, 2005
372005
Respiratory dysfunction progresses with age in Kcna1‐null mice, a model of sudden unexpected death in epilepsy
KA Simeone, J Hallgren, CS Bockman, A Aggarwal, V Kansal, L Netzel, ...
Epilepsia 59 (2), 345-357, 2018
322018
In vivo ketogenic diet treatment attenuates pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices from epileptic Kv1.1α knockout mice
TA Simeone, KK Samson, SA Matthews, KA Simeone
Epilepsia 55 (5), e44-e49, 2014
322014
L‐type calcium channel blockade reduces network activity in human epileptic hypothalamic hamartoma tissue
KA Simeone, S Sabesan, DY Kim, JF Kerrigan, JM Rho, TA Simeone
Epilepsia 52 (3), 531-540, 2011
222011
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