| Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease J Yao, RW Irwin, L Zhao, J Nilsen, RT Hamilton, RD Brinton Proceedings of the National Academy of Sciences 106 (34), 14670-14675, 2009 | 999 | 2009 |
| Estrogen: a master regulator of bioenergetic systems in the brain and body JR Rettberg, J Yao, RD Brinton Frontiers in neuroendocrinology 35 (1), 8-30, 2014 | 495 | 2014 |
| Perimenopause as a neurological transition state RD Brinton, J Yao, F Yin, WJ Mack, E Cadenas Nature reviews endocrinology 11 (7), 393-405, 2015 | 398 | 2015 |
| Progesterone and estrogen regulate oxidative metabolism in brain mitochondria RW Irwin, J Yao, RT Hamilton, E Cadenas, RD Brinton, J Nilsen Endocrinology 149 (6), 3167-3175, 2008 | 317 | 2008 |
| Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention F Ding, J Yao, JR Rettberg, S Chen, RD Brinton PloS one 8 (11), e79977, 2013 | 262 | 2013 |
| Altered brain energetics induces mitochondrial fission arrest in Alzheimer’s Disease L Zhang, S Trushin, TA Christensen, BV Bachmeier, B Gateno, ... Scientific reports 6 (1), 18725, 2016 | 198 | 2016 |
| 2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease J Yao, S Chen, Z Mao, E Cadenas, RD Brinton PloS one 6 (7), e21788, 2011 | 182 | 2011 |
| Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence J Yao, RT Hamilton, E Cadenas, RD Brinton Biochimica et Biophysica Acta (BBA)-General Subjects 1800 (10), 1121-1126, 2010 | 157 | 2010 |
| 17β-Estradiol regulates insulin-degrading enzyme expression via an ERβ/PI3-K pathway in hippocampus: relevance to Alzheimer's prevention L Zhao, J Yao, Z Mao, S Chen, Y Wang, RD Brinton Neurobiology of aging 32 (11), 1949-1963, 2011 | 147 | 2011 |
| Shift in brain metabolism in late onset Alzheimer’s disease: implications for biomarkers and therapeutic interventions J Yao, JR Rettberg, LP Klosinski, E Cadenas, RD Brinton Molecular aspects of medicine 32 (4-6), 247-257, 2011 | 147 | 2011 |
| Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease S Chen, JM Wang, RW Irwin, J Yao, L Liu, RD Brinton PloS one 6 (8), e24293, 2011 | 144 | 2011 |
| Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid J Yao, R Irwin, S Chen, R Hamilton, E Cadenas, RD Brinton Neurobiology of aging 33 (8), 1507-1521, 2012 | 142 | 2012 |
| Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice C Singh, L Liu, JM Wang, RW Irwin, J Yao, S Chen, S Henry, ... Neurobiology of aging 33 (8), 1493-1506, 2012 | 139 | 2012 |
| Estrogen regulation of mitochondrial bioenergetics: implications for prevention of Alzheimer’s disease J Yao, RD Brinton Advances in pharmacology 64, 327-371, 2012 | 111 | 2012 |
| The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity F Yin, J Yao, H Sancheti, T Feng, RC Melcangi, TE Morgan, CE Finch, ... Neurobiology of aging 36 (7), 2282-2295, 2015 | 103 | 2015 |
| Ovariectomy induces a shift in fuel availability and metabolism in the hippocampus of the female transgenic model of familial Alzheimer's F Ding, J Yao, L Zhao, Z Mao, S Chen, RD Brinton PloS one 8 (3), e59825, 2013 | 96 | 2013 |
| Selective oestrogen receptor modulators differentially potentiate brain mitochondrial function RW Irwin, J Yao, J To, RT Hamilton, E Cadenas, RD Brinton Journal of neuroendocrinology 24 (1), 236-248, 2012 | 93 | 2012 |
| Targeting the prodromal stage of Alzheimer's disease: bioenergetic and mitochondrial opportunities CC Caldwell, J Yao, RD Brinton Neurotherapeutics 12 (1), 66-80, 2015 | 87 | 2015 |
| Lipoic acid restores age‐associated impairment of brain energy metabolism through the modulation of A kt/JNK signaling and PGC 1α transcriptional pathway T Jiang, F Yin, J Yao, RD Brinton, E Cadenas Aging cell 12 (6), 1021-1031, 2013 | 83 | 2013 |
| Potentiation of brain mitochondrial function by S-equol and R/S-equol estrogen receptor β-selective phytoSERM treatments J Yao, L Zhao, Z Mao, S Chen, KC Wong, J To, RD Brinton Brain research 1514, 128-141, 2013 | 66 | 2013 |
