| Rational design of potent, small, synthetic allosteric inhibitors of thrombin PS Sidhu, A Liang, AY Mehta, MH Abdel Aziz, Q Zhou, UR Desai Journal of medicinal chemistry 54 (15), 5522-5531, 2011 | 75 | 2011 |
| Designing allosteric regulators of thrombin. Exosite 2 features multiple subsites that can be targeted by sulfated small molecules for inducing inhibition PS Sidhu, MH Abdel Aziz, A Sarkar, AY Mehta, Q Zhou, UR Desai Journal of medicinal chemistry 56 (12), 5059-5070, 2013 | 63 | 2013 |
| First steps in the direction of synthetic, allosteric, direct inhibitors of thrombin and factor Xa J Verghese, A Liang, PPS Sidhu, M Hindle, Q Zhou, UR Desai Bioorganic & medicinal chemistry letters 19 (15), 4126-4129, 2009 | 55 | 2009 |
| Identification of a novel, fast-acting GABAergic antidepressant KMJ McMurray, MJ Ramaker, AM Barkley-Levenson, PS Sidhu, PK Elkin, ... Molecular psychiatry 23 (2), 384-391, 2018 | 45 | 2018 |
| Designing allosteric regulators of thrombin. Monosulfated benzofuran dimers selectively interact with Arg173 of exosite 2 to induce inhibition MH Abdel Aziz, PS Sidhu, A Liang, JY Kim, PD Mosier, Q Zhou, DH Farrell, ... Journal of medicinal chemistry 55 (15), 6888-6897, 2012 | 44 | 2012 |
| Peroxisome proliferation-activated receptor δ agonist GW0742 interacts weakly with multiple nuclear receptors, including the vitamin D receptor P Nandhikonda, A Yasgar, AM Baranowski, PS Sidhu, MM McCallum, ... Biochemistry 52 (24), 4193-4203, 2013 | 36 | 2013 |
| 6-Hydroxyflavone and derivatives exhibit potent anti-inflammatory activity among mono-, di-and polyhydroxylated flavones in kidney mesangial cells X Wang, Z Wang, PS Sidhu, UR Desai, Q Zhou PLoS One 10 (3), e0116409, 2015 | 30 | 2015 |
| Development of novel vitamin D receptor–coactivator inhibitors PS Sidhu, N Nassif, MM McCallum, K Teske, B Feleke, NY Yuan, ... ACS medicinal chemistry letters 5 (2), 199-204, 2014 | 28 | 2014 |
| Anticancer activity of VDR-coregulator inhibitor PS121912 PS Sidhu, K Teske, B Feleke, NY Yuan, ML Guthrie, GB Fernstrum, ... Cancer chemotherapy and pharmacology 74, 787-798, 2014 | 26 | 2014 |
| Glo1 inhibitors for neuropsychiatric and anti-epileptic drug development KMJ McMurray, MG Distler, PS Sidhu, JM Cook, LA Arnold, AA Palmer, ... Biochemical Society Transactions 42 (2), 461-467, 2014 | 21 | 2014 |
| On scaffold hopping: challenges in the discovery of sulfated small molecules as mimetics of glycosaminoglycans PS Sidhu, PD Mosier, Q Zhou, UR Desai Bioorganic & medicinal chemistry letters 23 (1), 355-359, 2013 | 21 | 2013 |
| Genetic and pharmacological manipulation of glyoxalase 1 regulates voluntary ethanol consumption in mice KMJ McMurray, PS Sidhu, JM Cook, LA Arnold, AA Palmer Addiction biology 22 (2), 381-389, 2017 | 13 | 2017 |
| PT19c, Another Nonhypercalcemic Vitamin D2 Derivative, Demonstrates Antitumor Efficacy in Epithelial Ovarian and Endometrial Cancer Models N Kawar, S Maclaughlan, TC Horan, A Uzun, TS Lange, KK Kim, ... Genes & Cancer 4 (11-12), 524-534, 2013 | 13 | 2013 |
| Identification of VDR antagonists among nuclear receptor ligands using virtual screening K Teske, P Nandhikonda, JW Bogart, B Feleke, P Sidhu, N Yuan, ... Nuclear receptor research 1, 2014 | 11 | 2014 |
| Antitumor activity of 3-indolylmethanamines 31B and PS121912 ML Guthrie, PS Sidhu, EK Hill, TC Horan, P Nandhikonda, KA Teske, ... Anticancer research 35 (11), 6001-6007, 2015 | 7 | 2015 |
| Modulation of Transcription mediated by the Vitamin D Receptor and the Peroxisome Proliferator-Activated Receptor δ in the presence of GW0742 analogs K Teske, P Nandhikonda, JW Bogart, B Feleke, P Sidhu, N Yuan, ... Journal of biomolecular research & therapeutics 3 (1), 2014 | 6 | 2014 |
| One-pot synthesis protocol for highly functionalized benzofuran scaffold PS Sidhu Postdoc J 31, 36, 2013 | 5 | 2013 |
| Direct N-sec-alkylation of amides by reaction of α-halohydroxamates and sulfonylindoles: an approach to 3-indolyl methanamines Y Chen, X Guo, C Zhou, L Chen, T Kang Synlett 30 (07), 851-856, 2019 | 4 | 2019 |
| Parallel chemistry approach to identify novel nuclear receptor ligands based on the GW0742 scaffold KA Teske, G Rai, P Nandhikonda, PS Sidhu, B Feleke, A Simeonov, ... ACS combinatorial science 19 (10), 646-656, 2017 | 4 | 2017 |
| Allosteric regulation of dual function of thrombin PS Sidhu J Pharm Pharmacol 1, 1-10, 2013 | 4 | 2013 |
Leggy A ArnoldProfessor of Chemistry and Biochemistry, University of Wisconsin MilwaukeeVerified email at uwm.edu
