Tharan Srikumar
Tharan Srikumar
Bruker Ltd.
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Cited by
Cited by
A global genetic interaction network maps a wiring diagram of cellular function
M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ...
Science 353 (6306), 2016
miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4–NOT
MR Fabian, MK Cieplak, F Frank, M Morita, J Green, T Srikumar, B Nagar, ...
Nature structural & molecular biology 18 (11), 1211, 2011
Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress
C Bassi, J Ho, T Srikumar, RJO Dowling, C Gorrini, SJ Miller, TW Mak, ...
Science 341 (6144), 395-399, 2013
Controlled orientation of liquid-crystalline polythiophene semiconductors for high-performance organic thin-film transistors
Y Wu, P Liu, BS Ong, T Srikumar, N Zhao, G Botton, S Zhu
Applied Physics Letters 86 (14), 142102, 2005
The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis
E Rivkin, SM Almeida, DF Ceccarelli, YC Juang, TA MacLean, T Srikumar, ...
Nature 498 (7454), 318-324, 2013
Global map of SUMO function revealed by protein-protein interaction and genetic networks
T Makhnevych, Y Sydorskyy, X Xin, T Srikumar, FJ Vizeacoumar, ...
Molecular cell 33 (1), 124-135, 2009
A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen
Y Sheng, JH Hong, R Doherty, T Srikumar, J Shloush, GV Avvakumov, ...
Molecular & Cellular Proteomics 11 (8), 329-341, 2012
BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors
D Dingar, M Kalkat, PK Chan, T Srikumar, SD Bailey, WB Tu, E Coyaud, ...
Journal of proteomics 118, 95-111, 2015
A pathogen type III effector with a novel E3 ubiquitin ligase architecture
AU Singer, S Schulze, T Skarina, X Xu, H Cui, L Eschen-Lippold, M Egler, ...
PLoS Pathog 9 (1), e1003121, 2013
The catalytic subunit of Shiga-like toxin 1 interacts with ribosomal stalk proteins and is inhibited by their conserved C-terminal domain
AJ McCluskey, GMK Poon, E Bolewska-Pedyczak, T Srikumar, SM Jeram, ...
Journal of molecular biology 378 (2), 375-386, 2008
The dynamics and mechanism of SUMO chain deconjugation by SUMO-specific proteases
M Békés, J Prudden, T Srikumar, B Raught, MN Boddy, GS Salvesen
Journal of Biological Chemistry 286 (12), 10238-10247, 2011
RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks
M Bohgaki, T Bohgaki, S El Ghamrasni, T Srikumar, G Maire, S Panier, ...
Proceedings of the National Academy of Sciences 110 (52), 20982-20987, 2013
Using mass spectrometry to identify ubiquitin and ubiquitin‐like protein conjugation sites
SM Jeram, T Srikumar, PGA Pedrioli, B Raught
Proteomics 9 (4), 922-934, 2009
Global analysis of SUMO chain function reveals multiple roles in chromatin regulation
T Srikumar, MC Lewicki, M Costanzo, JM Tkach, H van Bakel, K Tsui, ...
Journal of Cell Biology 201 (1), 145-163, 2013
Src promotes GTPase activity of Ras via tyrosine 32 phosphorylation
S Bunda, P Heir, T Srikumar, JD Cook, K Burrell, Y Kano, JE Lee, ...
Proceedings of the National Academy of Sciences 111 (36), E3785-E3794, 2014
A novel mechanism for SUMO system control: regulated Ulp1 nucleolar sequestration
Y Sydorskyy, T Srikumar, SM Jeram, S Wheaton, FJ Vizeacoumar, ...
Molecular and cellular biology 30 (18), 4452-4462, 2010
A global S. cerevisiae small ubiquitin‐related modifier (SUMO) system interactome
T Srikumar, MC Lewicki, B Raught
Molecular systems biology 9 (1), 668, 2013
SUMO1 affects synaptic function, spine density and memory
S Matsuzaki, L Lee, E Knock, T Srikumar, M Sakurai, LN Hazrati, ...
Scientific reports 5 (1), 1-14, 2015
A genome-wide algal mutant library and functional screen identifies genes required for eukaryotic photosynthesis
X Li, W Patena, F Fauser, RE Jinkerson, S Saroussi, MT Meyer, N Ivanova, ...
Nature genetics 51 (4), 627-635, 2019
The S. cerevisiae SUMO stress response is a conjugation–deconjugation cycle that targets the transcription machinery
MC Lewicki, T Srikumar, E Johnson, B Raught
Journal of proteomics 118, 39-48, 2015
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