|Enhanced autoantigen expression in regenerating muscle cells in idiopathic inflammatory myopathy|
L Casciola-Rosen, K Nagaraju, P Plotz, K Wang, S Levine, E Gabrielson, ...
Journal of Experimental Medicine 201 (4), 591-601, 2005
|Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer|
B Wu, HM Moulton, PL Iversen, J Jiang, J Li, J Li, CF Spurney, A Sali, ...
Proceedings of the National Academy of Sciences 105 (39), 14814-14819, 2008
|Conditional up-regulation of MHC class I in skeletal muscle leads to self-sustaining autoimmune myositis and myositis-specific autoantibodies|
K Nagaraju, N Raben, L Loeffler, T Parker, PJ Rochon, E Lee, C Danning, ...
Proceedings of the National Academy of Sciences 97 (16), 9209-9214, 2000
|Histidyl–tRNA synthetase and asparaginyl–tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells|
OMZ Howard, HF Dong, D Yang, N Raben, K Nagaraju, A Rosen, ...
The Journal of experimental medicine 196 (6), 781-791, 2002
|Activation of the endoplasmic reticulum stress response in autoimmune myositis: potential role in muscle fiber damage and dysfunction|
K Nagaraju, L Casciola‐Rosen, I Lundberg, R Rawat, S Cutting, ...
Arthritis & Rheumatism 52 (6), 1824-1835, 2005
|Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy|
MD Grounds, HG Radley, GS Lynch, K Nagaraju, A De Luca
Neurobiology of disease 31 (1), 1-19, 2008
|Early onset of inflammation and later involvement of TGFβ in Duchenne muscular dystrophy|
YW Chen, K Nagaraju, M Bakay, O McIntyre, R Rawat, R Shi, EP Hoffman
Neurology 65 (6), 826-834, 2005
|Targeted disruption of the acid α-glucosidase gene in mice causes an illness with critical features of both infantile and adult human glycogen storage disease type II|
N Raben, K Nagaraju, E Lee, P Kessler, B Byrne, L Lee, M LaMarca, ...
Journal of Biological Chemistry 273 (30), 19086-19092, 1998
|A variety of cytokines and immunologically relevant surface molecules are expressed by normal human skeletal muscle cells under proinflammatory stimuli|
K Nagaraju, N Raben, G Merritt, L Loeffler, K Kirk, P Plotz
Clinical and experimental immunology 113 (3), 407, 1998
|Enzyme replacement therapy in the mouse model of Pompe disease|
N Raben, M Danon, AL Gilbert, S Dwivedi, B Collins, BL Thurberg, ...
Molecular genetics and metabolism 80 (1-2), 159-169, 2003
|Sources of variability and effect of experimental approach on expression profiling data interpretation|
M Bakay, YW Chen, R Borup, P Zhao, K Nagaraju, EP Hoffman
BMC bioinformatics 3 (1), 1-12, 2002
|Preclinical drug trials in the mdx mouse: Assessment of reliable and sensitive outcome measures|
CF Spurney, H Gordish‐Dressman, AD Guerron, A Sali, GS Pandey, ...
Muscle & Nerve: Official Journal of the American Association of …, 2009
|Behavioral and locomotor measurements using an open field activity monitoring system for skeletal muscle diseases|
KS Tatem, JL Quinn, A Phadke, Q Yu, H Gordish-Dressman, K Nagaraju
Journal of visualized experiments: JoVE, 2014
|Bodywide skipping of exons 45–55 in dystrophic mdx52 mice by systemic antisense delivery|
Y Aoki, T Yokota, T Nagata, A Nakamura, J Tanihata, T Saito, ...
Proceedings of the National Academy of Sciences 109 (34), 13763-13768, 2012
|VBP15, a novel anti‐inflammatory and membrane‐stabilizer, improves muscular dystrophy without side effects|
CR Heier, JM Damsker, Q Yu, BC Dillingham, T Huynh, ...
EMBO molecular medicine 5 (10), 1569-1585, 2013
|Inflammasome up-regulation and activation in dysferlin-deficient skeletal muscle|
R Rawat, TV Cohen, B Ampong, D Francia, A Henriques-Pons, ...
The American journal of pathology 176 (6), 2891-2900, 2010
|Replacing acid α-glucosidase in Pompe disease: recombinant and transgenic enzymes are equipotent, but neither completely clears glycogen from type II muscle fibers|
N Raben, T Fukuda, AL Gilbert, D De Jong, BL Thurberg, RJ Mattaliano, ...
Molecular Therapy 11 (1), 48-56, 2005
|Dystrophin-deficient cardiomyopathy in mouse: expression of Nox4 and Lox are associated with fibrosis and altered functional parameters in the heart|
CF Spurney, S Knoblach, EE Pistilli, K Nagaraju, GR Martin, EP Hoffman
Neuromuscular Disorders 18 (5), 371-381, 2008
|Suppression of autophagy permits successful enzyme replacement therapy in a lysosomal storage disorder—murine Pompe disease|
N Raben, C Schreiner, R Baum, S Takikita, S Xu, T Xie, R Myerowitz, ...
Autophagy 6 (8), 1078-1089, 2010
|Dysferlin deficiency enhances monocyte phagocytosis: a model for the inflammatory onset of limb-girdle muscular dystrophy 2B|
K Nagaraju, R Rawat, E Veszelovszky, R Thapliyal, A Kesari, S Sparks, ...
The American journal of pathology 172 (3), 774-785, 2008