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Maria Musgaard
Maria Musgaard
OMass Therapeutics
Verifierad e-postadress på omass.com
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P-type ATPases as drug targets: tools for medicine and science
L Yatime, MJ Buch-Pedersen, M Musgaard, JP Morth, AML Winther, ...
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1787 (4), 207-220, 2009
1642009
Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase
M Bublitz, M Musgaard, H Poulsen, L Thøgersen, C Olesen, B Schiøtt, ...
Journal of Biological Chemistry, 2013
1522013
Mutual adaptation of a membrane protein and its lipid bilayer during conformational changes
Y Sonntag, M Musgaard, C Olesen, B Schiøtt, JV Møller, P Nissen, ...
Nature communications 2 (1), 304, 2011
1332011
Binding and orientation of tricyclic antidepressants within the central substrate site of the human serotonin transporter
S Sinning, M Musgaard, M Jensen, K Severinsen, L Celik, H Koldsø, ...
Journal of Biological Chemistry 285 (11), 8363-8374, 2010
952010
Distinct Structural Pathways Coordinate the Activation of AMPA Receptor-Auxiliary Subunit Complexes
GB Dawe, M Musgaard, MRP Aurousseau, N Nayeem, T Green, ...
Neuron 89 (6), 1264-1276, 2016
772016
Defining the structural relationship between kainate-receptor deactivation and desensitization
GB Dawe, M Musgaard, ED Andrews, BA Daniels, MRP Aurousseau, ...
Nature Structural and Molecular Biology 20 (9), 1054, 2013
552013
Coupling structure with function in acid‐sensing ion channels: challenges in pursuit of proton sensors
ML Rook, M Musgaard, DM MacLean
The Journal of physiology 599 (2), 417-430, 2021
442021
Protonation states of important acidic residues in the central Ca2+ ion binding sites of the Ca2+-ATPase: a molecular modeling study
M Musgaard, L Thøgersen, B Schiøtt
Biochemistry 50 (51), 11109-11120, 2011
402011
Tracing cytoplasmic Ca 2+ ion and water access points in the Ca 2+-ATPase
M Musgaard, L Thøgersen, B Schiøtt, E Tajkhorshid
Biophysical journal 102 (2), 268-277, 2012
392012
β11-12 linker isomerization governs Acid-sensing ion channel desensitization and recovery
ML Rook, A Williamson, JD Lueck, M Musgaard, DM Maclean
Elife 9, e51111, 2020
322020
Role of the Cys loop and transmembrane domain in the allosteric modulation of α4β2 nicotinic acetylcholine receptors
C Alcaino, M Musgaard, T Minguez, S Mazzaferro, M Faundez, ...
Journal of Biological Chemistry 292 (2), 551-562, 2017
312017
Actions of Agonists, Fipronil and Ivermectin on the Predominant In Vivo Splice and Edit Variant (RDLbd, I/V) of the Drosophila GABA Receptor Expressed in Xenopus laevis Oocytes
K Lees, M Musgaard, S Suwanmanee, SD Buckingham, P Biggin, ...
PloS one 9 (5), e97468, 2014
272014
Steered Molecular Dynamics Simulations Predict Conformational Stability of Glutamate Receptors
M Musgaard, PC Biggin
Journal of Chemical Information and Modeling 56 (9), 1787-1797, 2016
262016
Kainate receptor pore‐forming and auxiliary subunits regulate channel block by a novel mechanism
PMGE Brown, MRP Aurousseau, M Musgaard, PC Biggin, D Bowie
The Journal of physiology 594 (7), 1821-1840, 2016
262016
Mutational analysis and modeling of negative allosteric modulator binding sites in AMPA receptors
C Stenum-Berg, M Musgaard, S Chavez-Abiega, CL Thisted, L Barrella, ...
Molecular pharmacology 96 (6), 835-850, 2019
222019
Functional Validation of Heteromeric Kainate Receptor Models
T Paramo, PMGE Brown, M Musgaard, D Bowie, PC Biggin
Biophysical Journal 113 (10), 2173-2177, 2017
182017
Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID: An emerging neurodevelopmental syndrome
V Ismail, LG Zachariassen, A Godwin, M Sahakian, S Ellard, KL Stals, ...
The American Journal of Human Genetics 109 (7), 1217-1241, 2022
162022
Insights into channel dysfunction from modelling and molecular dynamics simulations
M Musgaard, T Paramo, L Domicevica, OJ Andersen, PC Biggin
Neuropharmacology 132, 20-30, 2018
162018
The dynamics of camphor in the cytochrome P450 CYP101D2
S Vohra, M Musgaard, SG Bell, LL Wong, W Zhou, PC Biggin
Protein Science 22 (9), 1218-1229, 2013
152013
A single historical substitution drives an increase in acetylcholine receptor complexity
JR Emlaw, CJG Tessier, GD McCluskey, MS McNulty, Y Sheikh, ...
Proceedings of the National Academy of Sciences 118 (7), e2018731118, 2021
132021
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