|Epigenetic status of Gdnf in the ventral striatum determines susceptibility and adaptation to daily stressful events|
S Uchida, K Hara, A Kobayashi, K Otsuki, H Yamagata, T Hobara, ...
Neuron 69 (2), 359-372, 2011
|New series of antiprion compounds: pyrazolone derivatives have the potent activity of inhibiting protease-resistant prion protein accumulation|
A Kimata, H Nakagawa, R Ohyama, T Fukuuchi, S Ohta, T Suzuki, ...
Journal of medicinal chemistry 50 (21), 5053-5056, 2007
|Identification of cell-active lysine specific demethylase 1-selective inhibitors|
R Ueda, T Suzuki, K Mino, H Tsumoto, H Nakagawa, M Hasegawa, ...
Journal of the American Chemical Society 131 (48), 17536-17537, 2009
|Benzimidazole derivatives bearing substituted biphenyls as hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors: structure− activity relationship studies and …|
S Hirashima, T Suzuki, T Ishida, S Noji, S Yata, I Ando, M Komatsu, ...
Journal of medicinal chemistry 49 (15), 4721-4736, 2006
|Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors|
S Hamada, T Suzuki, K Mino, K Koseki, F Oehme, I Flamme, H Ozasa, ...
Journal of medicinal chemistry 53 (15), 5629-5638, 2010
|Highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate|
T Suzuki, A Kouketsu, Y Itoh, S Hisakawa, S Maeda, M Yoshida, ...
Journal of medicinal chemistry 49 (16), 4809-4812, 2006
|Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: identification of 2-[(4-diarylmethoxy) phenyl]-benzimidazole|
T Ishida, T Suzuki, S Hirashima, K Mizutani, A Yoshida, I Ando, S Ikeda, ...
Bioorganic & medicinal chemistry letters 16 (7), 1859-1863, 2006
|Novel inhibitors of human histone deacetylases: design, synthesis, enzyme inhibition, and cancer cell growth inhibition of SAHA-based non-hydroxamates|
T Suzuki, Y Nagano, A Kouketsu, A Matsuura, S Maruyama, M Kurotaki, ...
Journal of medicinal chemistry 48 (4), 1019-1032, 2005
|Lysine demethylases inhibitors|
T Suzuki, N Miyata
Journal of medicinal chemistry 54 (24), 8236-8250, 2011
|Design, synthesis, structure− selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors|
Y Itoh, T Suzuki, A Kouketsu, N Suzuki, S Maeda, M Yoshida, ...
Journal of medicinal chemistry 50 (22), 5425-5438, 2007
|Isoform-selective histone deacetylase inhibitors|
T Suzuki, Y Itoh, N Miyata
Current pharmaceutical design 14 (6), 529-544, 2008
|Rapid discovery of highly potent and selective inhibitors of histone deacetylase 8 using click chemistry to generate candidate libraries|
T Suzuki, Y Ota, M Ri, M Bando, A Gotoh, Y Itoh, H Tsumoto, PR Tatum, ...
Journal of medicinal chemistry 55 (22), 9562-9575, 2012
|Synthesis and activity of N-oxalylglycine and its derivatives as Jumonji C-domain-containing histone lysine demethylase inhibitors|
S Hamada, TD Kim, T Suzuki, Y Itoh, H Tsumoto, H Nakagawa, ...
Bioorganic & medicinal chemistry letters 19 (10), 2852-2855, 2009
|Non-hydroxamate histone deacetylase inhibitors|
T Suzuki, N Miyata
Current medicinal chemistry 12 (24), 2867-2880, 2005
|Identification of G protein-coupled receptor 120-selective agonists derived from PPARγ agonists|
T Suzuki, S Igari, A Hirasawa, M Hata, M Ishiguro, H Fujieda, Y Itoh, ...
Journal of medicinal chemistry 51 (23), 7640-7644, 2008
|Thiol-based SAHA analogues as potent histone deacetylase inhibitors|
T Suzuki, A Kouketsu, A Matsuura, A Kohara, S Ninomiya, K Kohda, ...
Bioorganic & medicinal chemistry letters 14 (12), 3313-3317, 2004
|The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1|
AE Tee, D Ling, C Nelson, B Atmadibrata, ME Dinger, N Xu, T Mizukami, ...
Oncotarget 5 (7), 1793, 2014
|Design, synthesis, inhibitory activity, and binding mode study of novel DNA methyltransferase 1 inhibitors|
T Suzuki, R Tanaka, S Hamada, H Nakagawa, N Miyata
Bioorganic & medicinal chemistry letters 20 (3), 1124-1127, 2010
|Superacid-Catalyzed Electrocyclization of 1-Phenyl-2-propen-1-ones to 1-Indanones. Kinetic and Theoretical Studies of Electrocyclization of Oxonium− Carbenium Dications|
T Suzuki, T Ohwada, K Shudo
Journal of the American Chemical Society 119 (29), 6774-6780, 1997
|Design, synthesis, and biological activity of a novel series of human sirtuin-2-selective inhibitors|
T Suzuki, MNA Khan, H Sawada, E Imai, Y Itoh, K Yamatsuta, N Tokuda, ...
Journal of medicinal chemistry 55 (12), 5760-5773, 2012