Bernhard Schmierer
Bernhard Schmierer
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TGFβ–SMAD signal transduction: molecular specificity and functional flexibility
B Schmierer, CS Hill
Nature reviews Molecular cell biology 8 (12), 970-982, 2007
CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response
E Haapaniemi, S Botla, J Persson, B Schmierer, J Taipale
Nature medicine 24 (7), 927-930, 2018
Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites
J Yan, M Enge, T Whitington, K Dave, J Liu, I Sur, B Schmierer, A Jolma, ...
Cell 154 (4), 801-813, 2013
Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor β-dependent nuclear accumulation of Smads
B Schmierer, CS Hill
Molecular and cellular biology 25 (22), 9845-9858, 2005
Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system
B Schmierer, AL Tournier, PA Bates, CS Hill
Proceedings of the National Academy of Sciences 105 (18), 6608-6613, 2008
Analysis of Smad nucleocytoplasmic shuttling in living cells
FJ Nicolás, K De Bosscher, B Schmierer, CS Hill
Journal of cell science 117 (18), 4113-4125, 2004
Catecholamines up‐regulate lipopolysaccharide‐induced IL‐6 production in human microvascular endothelial cells
A Gornikiewicz, T Sautner, C Brostjan, B Schmierer, R Függer, E Roth, ...
The FASEB Journal 14 (9), 1093-1100, 2000
Two highly related regulatory subunits of PP2A exert opposite effects on TGF-β/Activin/Nodal signalling
J Batut, B Schmierer, J Cao, LA Raftery, CS Hill, M Howell
Development 135 (17), 2927-2937, 2008
Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor
M Yang, W Ge, R Chowdhury, TDW Claridge, HB Kramer, B Schmierer, ...
Journal of Biological Chemistry 286 (9), 7648-7660, 2011
Controlling Long-Term Signaling: Receptor Dynamics Determine Attenuation and Refractory Behavior of the TGF-{beta} Pathway
P Vizan, DSJ Miller, I Gori, D Das, B Schmierer, CS Hill
Science Signaling 6 (305), ra106, 2013
Hypoxia-dependent sequestration of an oxygen sensor by a widespread structural motif can shape the hypoxic response-a predictive kinetic model
B Schmierer, B Novák, CJ Schofield
BMC systems biology 4 (1), 139, 2010
Activin A and follicle-stimulating hormone control tight junctions in avian granulosa cells by regulating occludin expression
MK Schuster, B Schmierer, A Shkumatava, K Kuchler
Biology of reproduction 70 (5), 1493-1499, 2004
Structural insights into the DNA-binding specificity of E2F family transcription factors
E Morgunova, Y Yin, A Jolma, K Dave, B Schmierer, A Popov, N Eremina, ...
Nature communications 6 (1), 1-8, 2015
Activin a signaling induces Smad2, but not Smad3, requiring protein kinase a activity in granulosa cells from the avian ovary
B Schmierer, MK Schuster, A Shkumatava, K Kuchler
Journal of Biological Chemistry 278 (23), 21197-21203, 2003
Activin and follicle-stimulating hormone signaling are required for long-term culture of functionally differentiated primary granulosa cells from the chicken ovary
B Schmierer, MK Schuster, A Shkumatava, K Kuchler
Biology of reproduction 68 (2), 620-627, 2003
Endothelial cells downregulate expression of the 70 kDa heat shock protein during hypoxia
R Oehler, B Schmierer, M Zellner, R Prohaska, E Roth
Biochemical and biophysical research communications 274 (2), 542-547, 2000
Upregulation of chicken p15INK4b at senescence and in the developing brain
SH Kim, J Rowe, H Fujii, R Jones, B Schmierer, BW Kong, K Kuchler, ...
Journal of cell science 119 (12), 2435-2443, 2006
CRISPR/Cas9 screening using unique molecular identifiers
B Schmierer, SK Botla, J Zhang, M Turunen, T Kivioja, J Taipale
Molecular systems biology 13 (10), 945, 2017
Cell cycle commitment in budding yeast emerges from the cooperation of multiple bistable switches
T Zhang, B Schmierer, B Novák
Open biology 1 (3), 110009, 2011
Studying Smad2 intranuclear diffusion dynamics by mathematical modelling of FRAP experiments
V González-Pérez, B Schmierer, CS Hill, RP Sear
Integrative Biology 3 (3), 197-207, 2011
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