David Tuveson
David Tuveson
Verifierad e-postadress på cshl.edu
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Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
GD Demetri, M Von Mehren, CD Blanke, AD Van den Abbeele, ...
New England Journal of Medicine 347 (7), 472-480, 2002
49312002
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-XL
J Zha, H Harada, E Yang, J Jockel, SJ Korsmeyer
Cell 87 (4), 619-628, 1996
30751996
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
KP Olive, MA Jacobetz, CJ Davidson, A Gopinathan, D McIntyre, ...
Science 324 (5933), 1457-1461, 2009
27852009
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
H Joensuu, PJ Roberts, M Sarlomo-Rikala, LC Andersson, ...
New England Journal of Medicine 344 (14), 1052-1056, 2001
25382001
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
SR Hingorani, EF Petricoin III, A Maitra, V Rajapakse, C King, ...
Cancer cell 4 (6), 437-450, 2003
21782003
Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
SR Hingorani, L Wang, AS Multani, C Combs, TB Deramaudt, RH Hruban, ...
Cancer cell 7 (5), 469-483, 2005
19132005
Restoration of p53 function leads to tumour regression in vivo
A Ventura, DG Kirsch, ME McLaughlin, DA Tuveson, J Grimm, L Lintault, ...
Nature 445 (7128), 661-665, 2007
17372007
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
EL Jackson, N Willis, K Mercer, RT Bronson, D Crowley, R Montoya, ...
Genes & development 15 (24), 3243-3248, 2001
17102001
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ...
Nature 491 (7424), 399-405, 2012
16382012
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ...
Nature 475 (7354), 106-109, 2011
15912011
Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome
KP Olive, DA Tuveson, ZC Ruhe, B Yin, NA Willis, RT Bronson, D Crowley, ...
Cell 119 (6), 847-860, 2004
12322004
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
I Varela, P Tarpey, K Raine, D Huang, CK Ong, P Stephens, H Davies, ...
Nature 469 (7331), 539-542, 2011
11672011
Somatic activation of the K-ras oncogene causes early onset lung cancer in mice
L Johnson, K Mercer, D Greenbaum, RT Bronson, D Crowley, ...
Nature 410 (6832), 1111-1116, 2001
11622001
KIT activation is a ubiquitous feature of gastrointestinal stromal tumors
BP Rubin, S Singer, C Tsao, A Duensing, ML Lux, R Ruiz, MK Hibbard, ...
Cancer research 61 (22), 8118-8121, 2001
11512001
Organoid models of human and mouse ductal pancreatic cancer
SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ...
Cell 160 (1-2), 324-338, 2015
10182015
Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma
AJ Aguirre, N Bardeesy, M Sinha, L Lopez, DA Tuveson, J Horner, ...
Genes & development 17 (24), 3112-3126, 2003
10062003
Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti–PD-L1 immunotherapy in pancreatic cancer
C Feig, JO Jones, M Kraman, RJB Wells, A Deonarine, DS Chan, ...
Proceedings of the National Academy of Sciences 110 (50), 20212-20217, 2013
9592013
The pancreas cancer microenvironment
C Feig, A Gopinathan, A Neesse, DS Chan, N Cook, DA Tuveson
Clinical cancer research 18 (16), 4266-4276, 2012
9362012
ATP citrate lyase inhibition can suppress tumor cell growth
G Hatzivassiliou, F Zhao, DE Bauer, C Andreadis, AN Shaw, D Dhanak, ...
Cancer cell 8 (4), 311-321, 2005
9072005
Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein–α
M Kraman, PJ Bambrough, JN Arnold, EW Roberts, L Magiera, JO Jones, ...
Science 330 (6005), 827-830, 2010
8182010
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Artiklar 1–20