Reinhold Penner, MD PhD
Reinhold Penner, MD PhD
Director of Research, The Queen's Medical Center
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Depletion of intracellular calcium stores activates a calcium current in mast cells
M Hoth, R Penner
Nature 355 (6358), 353-356, 1992
Store depletion and calcium influx
AB Parekh, R Penner
Physiological reviews 77 (4), 901-930, 1997
CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry
M Vig, C Peinelt, A Beck, DL Koomoa, D Rabah, M Koblan-Huberson, ...
Science 312 (5777), 1220-1223, 2006
LTRPC7 is a Mg· ATP-regulated divalent cation channel required for cell viability
MJS Nadler, MC Hermosura, K Inabe, AL Perraud, Q Zhu, AJ Stokes, ...
Nature 411 (6837), 590-595, 2001
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology
AL Perraud, A Fleig, CA Dunn, LA Bagley, P Launay, C Schmitz, ...
Nature 411 (6837), 595-599, 2001
Calcium release‐activated calcium current in rat mast cells.
M Hoth, R Penner
The Journal of physiology 465 (1), 359-386, 1993
A unified nomenclature for the superfamily of TRP cation channels
C Montell, L Birnbaumer, V Flockerzi, RJ Bindels, EA Bruford, MJ Caterina, ...
Molecular cell 9 (2), 229-231, 2002
Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7
C Schmitz, AL Perraud, CO Johnson, K Inabe, MK Smith, R Penner, ...
Cell 114 (2), 191-200, 2003
TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization
P Launay, A Fleig, AL Perraud, AM Scharenberg, R Penner, JP Kinet
Cell 109 (3), 397-407, 2002
Amplification of CRAC current by STIM1 and CRACM1 (Orai1)
C Peinelt, M Vig, DL Koomoa, A Beck, MJS Nadler, M Koblan-Huberson, ...
Nature cell biology 8 (7), 771-773, 2006
CRACM1 multimers form the ion-selective pore of the CRAC channel
M Vig, A Beck, JM Billingsley, A Lis, S Parvez, C Peinelt, DL Koomoa, ...
Current Biology 16 (20), 2073-2079, 2006
Regulation of calcium influx by second messengers in rat mast cells
R Penner, G Matthews, E Neher
Nature 334 (6182), 499-504, 1988
TRPM2-mediated Ca 2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
S Yamamoto, S Shimizu, S Kiyonaka, N Takahashi, T Wajima, Y Hara, ...
Nature medicine 14 (7), 738-747, 2008
TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions
MK Monteilh-Zoller, MC Hermosura, MJS Nadler, AM Scharenberg, ...
The Journal of general physiology 121 (1), 49-60, 2003
CRACM1, CRACM2, and CRACM3 are store-operated Ca2+ channels with distinct functional properties
A Lis, C Peinelt, A Beck, S Parvez, M Monteilh-Zoller, A Fleig, R Penner
Current Biology 17 (9), 794-800, 2007
TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+] i
D Prawitt, MK Monteilh-Zoller, L Brixel, C Spangenberg, B Zabel, A Fleig, ...
Proceedings of the national academy of sciences 100 (25), 15166-15171, 2003
Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels
M Kolisek, A Beck, A Fleig, R Penner
Molecular cell 18 (1), 61-69, 2005
A GTP-dependent step in the activation mechanism of capacitative calcium influx.
C Fasolato, M Hoth, R Penner
Journal of Biological Chemistry 268 (28), 20737-20740, 1993
CaT1 and the calcium release-activated calcium channel manifest distinct pore properties
T Voets, J Prenen, A Fleig, R Vennekens, H Watanabe, JGJ Hoenderop, ...
Journal of Biological Chemistry 276 (51), 47767-47770, 2001
TRPM4 regulates calcium oscillations after T cell activation
P Launay, H Cheng, S Srivatsan, R Penner, A Fleig, JP Kinet
Science 306 (5700), 1374-1377, 2004
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