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Frederik De Smet
Frederik De Smet
Professor, KULeuven
Verifierad e-postadress på kuleuven.be - Startsida
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Gene prioritization through genomic data fusion
S Aerts, D Lambrechts, S Maity, P Van Loo, B Coessens, F De Smet, ...
Nature biotechnology 24 (5), 537-544, 2006
11112006
Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization
M Mazzone, D Dettori, RL de Oliveira, S Loges, T Schmidt, B Jonckx, ...
Cell 136 (5), 839-851, 2009
9202009
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system
X Lu, F Le Noble, L Yuan, Q Jiang, B De Lafarge, D Sugiyama, C Bréant, ...
Nature 432 (7014), 179-186, 2004
6482004
Mechanisms of vessel branching: filopodia on endothelial tip cells lead the way
F De Smet, I Segura, K De Bock, PJ Hohensinner, P Carmeliet
Arteriosclerosis, thrombosis, and vascular biology 29 (5), 639-649, 2009
5102009
VEGF: A modifier of the del22q11 (DiGeorge) syndrome?
I Stalmans, D Lambrechts, F De Smet, S Jansen, J Wang, S Maity, ...
Nature medicine 9 (2), 173-182, 2003
3382003
An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates
J Goveia, K Rohlenova, F Taverna, L Treps, LC Conradi, A Pircher, ...
Cancer cell 37 (1), 21-36. e13, 2020
3332020
Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization
AR Pombo Antunes, I Scheyltjens, F Lodi, J Messiaen, A Antoranz, ...
Nature neuroscience 24 (4), 595-610, 2021
3122021
FGF-dependent metabolic control of vascular development
P Yu, K Wilhelm, A Dubrac, JK Tung, TC Alves, JS Fang, Y Xie, J Zhu, ...
Nature 545 (7653), 224-228, 2017
3102017
Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way
P Carmeliet, F De Smet, S Loges, M Mazzone
Nature reviews Clinical oncology 6 (6), 315-326, 2009
2802009
Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity
L Vanderbeke, P Van Mol, Y Van Herck, F De Smet, S Humblet-Baron, ...
Nature communications 12 (1), 4117, 2021
2012021
Single-cell RNA sequencing maps endothelial metabolic plasticity in pathological angiogenesis
K Rohlenova, J Goveia, M García-Caballero, A Subramanian, J Kalucka, ...
Cell metabolism 31 (4), 862-877. e14, 2020
1922020
Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties
F Bono, F De Smet, C Herbert, K De Bock, M Georgiadou, P Fons, M Tjwa, ...
Cancer cell 23 (4), 477-488, 2013
1432013
Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish
I Geudens, R Herpers, K Hermans, I Segura, C Ruiz de Almodovar, ...
Arteriosclerosis, thrombosis, and vascular biology 30 (9), 1695-1702, 2010
1432010
Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling
C Herbert, U Schieborr, K Saxena, J Juraszek, F De Smet, C Alcouffe, ...
Cancer cell 23 (4), 489-501, 2013
1352013
Role of neural guidance signals in blood vessel navigation
M Autiero, F De Smet, F Claes, P Carmeliet
Cardiovascular research 65 (3), 629-638, 2005
1262005
Allosteric targeting of receptor tyrosine kinases
F De Smet, A Christopoulos, P Carmeliet
Nature biotechnology 32 (11), 1113-1120, 2014
932014
The neurovascular link in health and disease: an update
I Segura, F De Smet, PJ Hohensinner, CR de Almodovar, P Carmeliet
Trends in molecular medicine 15 (10), 439-451, 2009
782009
Differential endothelial transcriptomics identifies semaphorin 3G as a vascular class 3 semaphorin
S Kutschera, H Weber, A Weick, F De Smet, G Genove, M Takemoto, ...
Arteriosclerosis, thrombosis, and vascular biology 31 (1), 151-159, 2011
742011
De novo design of a biologically active amyloid
R Gallardo, M Ramakers, F De Smet, F Claes, L Khodaparast, ...
Science 354 (6313), aah4949, 2016
712016
Increased IL‐10‐producing regulatory T cells are characteristic of severe cases of COVID‐19
J Neumann, T Prezzemolo, L Vanderbeke, CP Roca, M Gerbaux, ...
Clinical & translational immunology 9 (11), e1204, 2020
622020
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