Thomas Eisenhaure
Thomas Eisenhaure
Broad Institute
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A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
J Moffat, DA Grueneberg, X Yang, SY Kim, AM Kloepfer, G Hinkle, ...
Cell 124 (6), 1283-1298, 2006
An immunogenic personal neoantigen vaccine for patients with melanoma
PA Ott, Z Hu, DB Keskin, SA Shukla, J Sun, DJ Bozym, W Zhang, A Luoma, ...
Nature 547 (7662), 217-221, 2017
CRISPR-Cas9 knockin mice for genome editing and cancer modeling
RJ Platt, S Chen, Y Zhou, MJ Yim, L Swiech, HR Kempton, JE Dahlman, ...
Cell 159 (2), 440-455, 2014
Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses
I Amit, M Garber, N Chevrier, AP Leite, Y Donner, T Eisenhaure, ...
Science 326 (5950), 257-263, 2009
Common genetic variants modulate pathogen-sensing responses in human dendritic cells
MN Lee, C Ye, AC Villani, T Raj, W Li, TM Eisenhaure, SH Imboywa, ...
Science 343 (6175), 2014
Dynamic profiling of the protein life cycle in response to pathogens
M Jovanovic, MS Rooney, P Mertins, D Przybylski, N Chevrier, R Satija, ...
Science 347 (6226), 2015
A genome-wide CRISPR screen in primary immune cells to dissect regulatory networks
O Parnas, M Jovanovic, TM Eisenhaure, RH Herbst, A Dixit, CJ Ye, ...
Cell 162 (3), 675-686, 2015
Mass spectrometry profiling of HLA-associated peptidomes in mono-allelic cells enables more accurate epitope prediction
JG Abelin, DB Keskin, S Sarkizova, CR Hartigan, W Zhang, J Sidney, ...
Immunity 46 (2), 315-326, 2017
Systematic discovery of TLR signaling components delineates viral-sensing circuits
N Chevrier, P Mertins, MN Artyomov, AK Shalek, M Iannacone, ...
Cell 147 (4), 853-867, 2011
Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition
ND Udeshi, DR Mani, T Eisenhaure, P Mertins, JD Jaffe, KR Clauser, ...
Molecular & Cellular Proteomics 11 (5), 148-159, 2012
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry
F Zhang, K Wei, K Slowikowski, CY Fonseka, DA Rao, S Kelly, ...
Nature immunology 20 (7), 928-942, 2019
The immune cell landscape in kidneys of patients with lupus nephritis
A Arazi, DA Rao, CC Berthier, A Davidson, Y Liu, PJ Hoover, A Chicoine, ...
Nature immunology 20 (7), 902-914, 2019
Translation Rate of Human Tyrosinase Determines ItsN-Linked Glycosylation Level
A Újvári, R Aron, T Eisenhaure, E Cheng, HA Parag, Y Smicun, ...
Journal of Biological Chemistry 276 (8), 5924-5931, 2001
Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli
I Gat-Viks, N Chevrier, R Wilentzik, T Eisenhaure, R Raychowdhury, ...
Nature biotechnology 31 (4), 342-349, 2013
The Rho guanine nucleotide exchange factor Lsc homo-oligomerizes and is negatively regulated through domains in its carboxyl terminus that are absent in novel splenic isoforms
TM Eisenhaure, SA Francis, LD Willison, SR Coughlin, DJ Lerner
Journal of Biological Chemistry 278 (33), 30975-30984, 2003
Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue
LT Donlin, DA Rao, K Wei, K Slowikowski, MJ McGeachy, JD Turner, ...
Arthritis research & therapy 20 (1), 139, 2018
A large peptidome dataset improves HLA class I epitope prediction across most of the human population
S Sarkizova, S Klaeger, PM Le, LW Li, G Oliveira, H Keshishian, ...
Nature Biotechnology 38 (2), 199-209, 2020
RNA interference screen in primary human T cells reveals FLT3 as a modulator of IL-10 levels
AL Astier, G Beriou, TM Eisenhaure, SM Anderton, DA Hafler, N Hacohen
The journal of immunology 184 (2), 685-693, 2010
Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation
YY Lan, JM Heather, T Eisenhaure, CS Garris, D Lieb, R Raychowdhury, ...
Aging Cell 18 (2), e12901, 2019
A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression
KM Mahoney, SA Shukla, N Patsoukis, A Chaudhri, EP Browne, A Arazi, ...
Cancer Immunology, Immunotherapy 68 (3), 421-432, 2019
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