| Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and … CB Moraes, MA Giardini, H Kim, CH Franco, AM Araujo-Junior, ... Scientific reports 4, 4703, 2014 | 221 | 2014 |
| Drug discovery for Chagas disease should consider Trypanosoma cruzi strain diversity B Zingales, MA Miles, CB Moraes, A Luquetti, F Guhl, AG Schijman, ... Memórias do Instituto Oswaldo Cruz 109, 828-833, 2014 | 149 | 2014 |
| Amazonian plant natural products: perspectives for discovery of new antimalarial drug leads AM Pohlit, RBS Lima, G Frausin, SCP Lopes, CB Moraes, P Cravo, ... Molecules 18 (8), 9219-9240, 2013 | 58 | 2013 |
| Current and Future Chemotherapy for Chagas Disease L Gaspar, C B Moraes, L H Freitas-Junior, S Ferrari, L Costantino, ... Current medicinal chemistry 22 (37), 4293-4312, 2015 | 54 | 2015 |
| Bacteria from Antarctic environments: diversity and detection of antimicrobial, antiproliferative, and antiparasitic activities TR Silva, AWF Duarte, MRZ Passarini, ALTG Ruiz, CH Franco, ... Polar Biology 41, 1505-1519, 2018 | 50 | 2018 |
| Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity F Di Pisa, G Landi, L Dello Iacono, C Pozzi, C Borsari, S Ferrari, ... Molecules 22 (3), 426, 2017 | 47 | 2017 |
| An image-based algorithm for precise and accurate high throughput assessment of drug activity against the human parasite Trypanosoma cruzi S Moon, JL Siqueira-Neto, CB Moraes, G Yang, M Kang, ... PloS one 9 (2), e87188, 2014 | 47 | 2014 |
| Drug Discovery for Human African Trypanosomiasis Identification of Novel Scaffolds by the Newly Developed HTS SYBR Green Assay for Trypanosoma brucei J Faria, CB Moraes, R Song, BS Pascoalino, N Lee, JL Siqueira-Neto, ... Journal of biomolecular screening 20 (1), 70-81, 2015 | 45 | 2015 |
| Hydrocephalus and arthrogryposis in an immunocompetent mouse model of ZIKA teratogeny: A developmental study J Xavier-Neto, M Carvalho, BS Pascoalino, AC Cardoso, ÂMS Costa, ... PLoS neglected tropical diseases 11 (2), e0005363, 2017 | 43 | 2017 |
| A comparative study of warheads for design of cysteine protease inhibitors DG Silva, JFR Ribeiro, D De Vita, L Cianni, CH Franco, LH Freitas-Junior, ... Bioorganic & medicinal chemistry letters 27 (22), 5031-5035, 2017 | 42 | 2017 |
| Drug Discovery for Chagas Disease: Impact of Different Host Cell Lines on Assay Performance and Hit Compound Selection CH Franco, LM Alcântara, E Chatelain, L Freitas-Junior, CB Moraes Tropical medicine and infectious disease 4 (2), 82, 2019 | 39 | 2019 |
| Aryl thiosemicarbazones for the treatment of trypanosomatidic infections P Linciano, CB Moraes, LM Alcantara, CH Franco, B Pascoalino, ... European journal of medicinal chemistry 146, 423-434, 2018 | 37 | 2018 |
| Design, synthesis and antitrypanosomal activity of some nitrofurazone 1, 2, 4-triazolic bioisosteric analogues FT Silva, CH Franco, DC Favaro, LH Freitas-Junior, CB Moraes, ... European Journal of Medicinal Chemistry 121, 553-560, 2016 | 34 | 2016 |
| Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display … E Uliassi, G Fiorani, RL Krauth-Siegel, C Bergamini, R Fato, G Bianchini, ... European journal of medicinal chemistry 141, 138-148, 2017 | 32 | 2017 |
| Computer-aided discovery of two novel chalcone-like compounds active and selective against Leishmania infantum MN Gomes, LM Alcântara, BJ Neves, CC Melo-Filho, LH Freitas-Junior, ... Bioorganic & Medicinal Chemistry Letters 27 (11), 2459-2464, 2017 | 32 | 2017 |
| An essential nuclear protein in trypanosomes is a component of mRNA transcription/export pathway M Serpeloni, CB Moraes, JRC Muniz, MCM Motta, ASP Ramos, ... PLoS One 6 (6), e20730, 2011 | 32 | 2011 |
| The translational challenge in Chagas disease drug development JM Kratz, KR Gonçalves, L Romera, CB Moraes, P Bittencourt-Cunha, ... Memórias do Instituto Oswaldo Cruz 117, 2022 | 30 | 2022 |
| Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery P Linciano, A Dawson, I Pöhner, DM Costa, MS Sá, A Cordeiro-da-Silva, ... ACS omega 2 (9), 5666-5683, 2017 | 30 | 2017 |
| Quantum dots: a new tool for anti-malarial drug assays MJ Ku, FM Dossin, Y Choi, CB Moraes, J Ryu, R Song, LH Freitas-Junior Malaria journal 10 (1), 118, 2011 | 30 | 2011 |
| Non-Toxic Dimeric Peptides Derived from the Bothropstoxin-I Are Potent SARS-CoV-2 and Papain-like Protease Inhibitors MCLC Freire, GD Noske, NV Bitencourt, PRS Sanches, NA Santos-Filho, ... Molecules 26 (16), 4896, 2021 | 28 | 2021 |
