| Protein kinase C-related kinase 1 and 2 play an essential role in thromboxane-mediated neoplastic responses in prostate cancer AG O'Sullivan, EP Mulvaney, PB Hyland, BT Kinsella Oncotarget 6 (28), 26437, 2015 | 29 | 2015 |
| Urocortin-2 improves right ventricular function and attenuates pulmonary arterial hypertension R Adao, P Mendes-Ferreira, D Santos-Ribeiro, C Maia-Rocha, ... Cardiovascular research 114 (8), 1165-1177, 2018 | 28 | 2018 |
| Interaction of the human prostacyclin receptor with the PDZ adapter protein PDZK1: role in endothelial cell migration and angiogenesis EC Turner, EP Mulvaney, HM Reid, BT Kinsella Molecular biology of the cell 22 (15), 2664-2679, 2011 | 27 | 2011 |
| NTP42, a novel antagonist of the thromboxane receptor, attenuates experimentally induced pulmonary arterial hypertension EP Mulvaney, HM Reid, L Bialesova, A Bouchard, D Salvail, BT Kinsella BMC pulmonary medicine 20, 1-16, 2020 | 21 | 2020 |
| Regulation of protein kinase C-related kinase (PRK) signalling by the TPα and TPβ isoforms of the human thromboxane A2 receptor: Implications for thromboxane-and androgen … AG O'Sullivan, EP Mulvaney, BT Kinsella Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (4), 838-856, 2017 | 21 | 2017 |
| Transcriptional regulation of the human thromboxane A2 receptor gene by Wilms' tumor (WT) 1 and hypermethylated in cancer (HIC) 1 in prostate and breast cancers GL Keating, HM Reid, SB Eivers, EP Mulvaney, BT Kinsella Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (6), 476-492, 2014 | 19 | 2014 |
| Interaction of angio-associated migratory cell protein with the TPα and TPβ isoforms of the human thromboxane A2 receptor HM Reid, K Wikström, DJ Kavanagh, EP Mulvaney, BT Kinsella Cellular signalling 23 (4), 700-717, 2011 | 16 | 2011 |
| Expression of the TPα and TPβ isoforms of the thromboxane prostanoid receptor (TP) in prostate cancer: Clinical significance and diagnostic potential EP Mulvaney, C Shilling, SB Eivers, AS Perry, A Bjartell, EW Kay, ... Oncotarget 7 (45), 73171, 2016 | 11 | 2016 |
| Efficacy of the thromboxane receptor antagonist NTP42 alone, or in combination with sildenafil, in the sugen/hypoxia-induced model of pulmonary arterial hypertension EP Mulvaney, HM Reid, L Bialesova, P Mendes-Ferreira, R Adao, ... European Journal of Pharmacology 889, 173658, 2020 | 9 | 2020 |
| Molecular analysis of the prostacyclin receptor’s interaction with the PDZ1 domain of its adaptor protein PDZK1 G Birrane, EP Mulvaney, R Pal, BT Kinsella, O Kocher PloS one 8 (2), e53819, 2013 | 9 | 2013 |
| Regulated expression of the TPβ isoform of the human T prostanoid receptor by the tumour suppressors FOXP1 and NKX3. 1: Implications for the role of thromboxane in prostate cancer AG O'Sullivan, SB Eivers, EP Mulvaney, BT Kinsella Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (12 …, 2017 | 7 | 2017 |
| The thromboxane receptor antagonist NTP42 promotes beneficial adaptation and preserves cardiac function in experimental models of right heart overload EP Mulvaney, F Renzo, R Adão, E Dupre, L Bialesova, V Salvatore, ... Frontiers in cardiovascular medicine 9, 1063967, 2022 | 6 | 2022 |
| Differential expression of the TPα and TPβ isoforms of the human T Prostanoid receptor during chronic inflammation of the prostate: Role for FOXP1 in the transcriptional … EP Mulvaney, ÁG O'Sullivan, SB Eivers, HM Reid, BT Kinsella Experimental and molecular pathology 110, 104277, 2019 | 6 | 2019 |
| Identification of α-helix 4 (α4) of Rab11a as a novel Rab11-binding domain (RBD): interaction of Rab11a with the prostacyclin receptor EP Mulvaney, F O'Meara, AR Khan, DJ O'Connell, BT Kinsella Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (10), 1819-1832, 2017 | 5 | 2017 |
| Interaction of the human prostacyclin receptor and the NHERF4 family member intestinal and kidney enriched PDZ protein (IKEPP) HM Reid, EC Turner, EP Mulvaney, PB Hyland, C McLean, BT Kinsella Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (10), 1998-2012, 2012 | 4 | 2012 |
| Efficacy of the novel thromboxane receptor antagonist NTP42 alone, or in combination with Sildenafil, in the sugen/hypoxia-induced model of pulmonary arterial hypertension T Kinsella, E Mulvaney, HM Reid Eur. Heart J 40 (10.1093), 2019 | 2 | 2019 |
| Urocortin-2 improves right ventricular function and attenuates experimental pulmonary arterial hypertension R Adao, P Mendes-Ferreira, D Santos-Ribeiro, C Maia-Rocha, L Pimentel, ... European Respiratory Journal 52 (suppl 62), 2018 | 1 | 2018 |
| Evaluation of NTP42, a novel thromboxane receptor antagonist, in a first-in-human phase I clinical trial HM Reid, M Maginn, CM Perkins, EP Mulvaney, M Boyce, T Yamamoto, ... Frontiers in Pharmacology 14, 1296188, 2023 | | 2023 |
| Thromboxane receptor antagonist formulations BT Kinsella, H Reid, E Mulvaney US Patent App. 18/014,438, 2023 | | 2023 |
| A Phase I Clinical Trial Assessing the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of NTP42: KVA4, a Novel Thromboxane Receptor Antagonist, in Healthy Subjects BT Kinsella, HM Reid, EP Mulvaney, M Boyce, T Yamamoto, M Maginn, ... B59. BREAKING BAD: NEW DRUGS AND FORMULATIONS FOR PULMONARY HYPERTENSION AND …, 2023 | | 2023 |
Watson RWUniversity College DublinVerifierad e-postadress på ucd.ie
