Zuojun Guo
Zuojun Guo
Genomics Institute of Novartis Research Foundation and Center for Theoretical Biological Physics in
Verifierad e-postadress på gnf.org
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Probing the α‐helical structural stability of stapled p53 peptides: molecular dynamics simulations and analysis
Z Guo, U Mohanty, J Noehre, TK Sawyer, W Sherman, G Krilov
Chemical biology & drug design 75 (4), 348-359, 2010
3592010
Discovering ordered phases of block copolymers: New results from a generic Fourier-space approach
Z Guo, G Zhang, F Qiu, H Zhang, Y Yang, AC Shi
Physical review letters 101 (2), 028301, 2008
1392008
Compounds and methods for kinase modulation, and indications therefor
J Lin, PN Ibrahim, A Albers, J Buell, Z Guo, P Pham, H Powers, S Shi, ...
US Patent 10,160,747, 2018
28*2018
Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists
S Liu, LA Dakin, L Xing, JM Withka, PV Sahasrabudhe, W Li, ME Banker, ...
Scientific reports 6 (1), 1-12, 2016
272016
Identification of protein–ligand binding sites by the level-set variational implicit-solvent approach
Z Guo, B Li, LT Cheng, S Zhou, JA McCammon, J Che
Journal of Chemical Theory and Computation 11 (2), 753-765, 2015
242015
Evaluation of Hydration Free Energy by Level-Set Variational Implicit-Solvent Model with Coulomb-Field Approximation
Z Guo, B Li, J Dzubiella, LT Cheng, JA McCammon, J Che
Journal of Chemical Theory and Computation, 2013
242013
Compounds and methods for IDO and TDO modulation, and indications therefor
J Zhang, H Powers, A Albers, P Pham, G Wu, J Buell, W Spevak, Z Guo, ...
US Patent 10,508,085, 2019
172019
Heterogeneous hydration of p53/MDM2 complex
Z Guo, B Li, J Dzubiella, LT Cheng, JA McCammon, J Che
Journal of Chemical Theory and Computation 10 (3), 1302-1313, 2014
172014
DNA on a tube: electrostatic contribution to stiffness
Z Guo, CH Taubes, JE Oh, LJ Maher Iii, U Mohanty
The Journal of Physical Chemistry B 112 (50), 16163-16169, 2008
152008
Probing the Origin of Structural Stability of Single and Double Stapled p53 Peptide Analogs Bound to MDM 2
Z Guo, K Streu, G Krilov, U Mohanty
Chemical biology & drug design 83 (6), 631-642, 2014
142014
Target the more druggable protein states in a highly dynamic protein–protein interaction system
Z Guo, A Thorarensen, J Che, L Xing
Journal of chemical information and modeling 56 (1), 35-45, 2016
122016
Role of large thermal fluctuations and magnesium ions in t-RNA selectivity of the ribosome
Z Guo, M Gibson, S Sitha, S Chu, U Mohanty
Proceedings of the National Academy of Sciences 108 (10), 3947-3951, 2011
72011
Coated, agglomerated phytochemicals
V Kuellmer, R Shukla
US Patent App. 10/428,067, 2004
52004
Compounds and methods for ido and tdo modulation, and indications therefor
J Zhang, H Powers, A Albers, P Pham, G Wu, J Buell, W Spevak, Z Guo, ...
US Patent App. 16/358,608, 2019
12019
Data Quality Assurance and Statistical Analysis of High Throughput Screenings for Drug Discovery
Y Zhong, Z Guo, J Che
Frontiers in Computational Chemistry, 389-425, 2015
12015
Structural Stability of Nucleic Acids and Peptides: a Theoretical and Computational Study
Z Guo
Boston College, 2012
12012
Compounds and methods for kinase modulation
C Zhang, G Wu, W Spevak, Z Guo, Y Zhang
US Patent 10,428,067, 2019
2019
Targeting the more" druggable" protein states of Bcl-xL in a highly dynamic protein-protein interaction system
L Xing, Z Guo, A Thorarensen, S Thaisrivongs
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015
2015
Study of protein-protein interface inhibition through molecular dynamics and free energy simulations: Application to staple peptides, small molecules, and antibodies
G Krilov, W Sherman, Z Guo, K Streu, U Mohanty, T Sawyer
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014
2014
Simulation Study of Stapled Alpha-Helical P53 Peptide Analogs: probing the Relationship between Structural Stability and Biological Potency
U Mohanty, Z Guo, J Nohere, T Sawyer, W Sherman, G Krilov
Biophysical Journal 98 (3), 463a, 2010
2010
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Artiklar 1–20