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Trond Ulven
Trond Ulven
Professor of Medicinal Chemistry, University of Copenhagen
Verified email at sund.ku.dk - Homepage
Title
Cited by
Cited by
Year
Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets
T Ulven
Frontiers in endocrinology 3, 111, 2012
2842012
Gut dysbiosis during influenza contributes to pulmonary pneumococcal superinfection through altered short-chain fatty acid production
V Sencio, A Barthelemy, LP Tavares, MG Machado, D Soulard, C Cuinat, ...
Cell reports 30 (9), 2934-2947. e6, 2020
2552020
Emerging roles of DP and CRTH2 in allergic inflammation
E Kostenis, T Ulven
Trends in molecular medicine 12 (4), 148-158, 2006
2442006
Complex pharmacology of free fatty acid receptors
G Milligan, B Shimpukade, T Ulven, BD Hudson
Chemical Reviews 117 (1), 67-110, 2017
2232017
The pharmacology of TUG-891, a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), demonstrates both potential opportunity and possible challenges to …
BD Hudson, B Shimpukade, AE Mackenzie, AJ Butcher, JD Pediani, ...
Molecular pharmacology 84 (5), 710-725, 2013
1932013
Discovery of a potent and selective GPR120 agonist
B Shimpukade, BD Hudson, CK Hovgaard, G Milligan, T Ulven
Journal of medicinal chemistry 55 (9), 4511-4515, 2012
1892012
Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation
L Uller, JM Mathiesen, L Alenmyr, M Korsgren, T Ulven, T Högberg, ...
Respiratory research 8, 1-10, 2007
1612007
Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival
A Theiler, T Bärnthaler, W Platzer, G Richtig, M Peinhaupt, S Rittchen, ...
Journal of Allergy and Clinical Immunology 144 (3), 764-776, 2019
1502019
Discovery of Potent and Selective Agonists for the Free Fatty Acid Receptor 1 (FFA1/GPR40), a Potential Target for the Treatment of Type II Diabetes
E Christiansen, C Urban, N Merten, K Liebscher, KK Karlsen, A Hamacher, ...
Journal of medicinal chemistry 51 (22), 7061-7064, 2008
1492008
Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation
NRV Dragano, C Solon, AF Ramalho, RF de Moura, DS Razolli, ...
Journal of neuroinflammation 14, 1-16, 2017
1392017
Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3
J Schmidt, NJ Smith, E Christiansen, IG Tikhonova, M Grundmann, ...
Journal of Biological Chemistry 286 (12), 10628-10640, 2011
1282011
Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3
BD Hudson, IG Tikhonova, SK Pandey, T Ulven, G Milligan
Journal of Biological Chemistry 287 (49), 41195-41209, 2012
1272012
Chemical Synthesis and Biological Evaluation of cis- and trans-12,13-Cyclopropyl and 12,13-Cyclobutyl Epothilones and Related Pyridine Side Chain Analogues
KC Nicolaou, K Namoto, A Ritzen, T Ulven, M Shoji, J Li, G D'Amico, ...
Journal of the American Chemical Society 123 (38), 9313-9323, 2001
1272001
Identification of indole derivatives exclusively interfering with a G protein-independent signaling pathway of the prostaglandin D2 receptor CRTH2
JM Mathiesen, T Ulven, L Martini, LO Gerlach, A Heinemann, E Kostenis
Molecular pharmacology 68 (2), 393-402, 2005
1192005
The oxygen‐mediated synthesis of 1, 3‐butadiynes in continuous flow: Using Teflon AF‐2400 to effect gas/liquid contact
TP Petersen, A Polyzos, M O'Brien, T Ulven, IR Baxendale, SV Ley
ChemSusChem 5 (2), 274-277, 2012
1182012
Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseases
E Christiansen, KR Watterson, CJ Stocker, E Sokol, L Jenkins, K Simon, ...
British Journal of Nutrition 113 (11), 1677-1688, 2015
1132015
Dietary fatty acids and their potential for controlling metabolic diseases through activation of FFA4/GPR120
T Ulven, E Christiansen
Annual Review of Nutrition 35, 239-263, 2015
1082015
Minor structural modifications convert the dual TP/CRTH2 antagonist ramatroban into a highly selective and potent CRTH2 antagonist
T Ulven, E Kostenis
Journal of medicinal chemistry 48 (4), 897-900, 2005
1062005
Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor
BD Hudson, ME Due-Hansen, E Christiansen, AM Hansen, AE Mackenzie, ...
Journal of Biological Chemistry 288 (24), 17296-17312, 2013
1042013
A protocol for amide bond formation with electron deficient amines and sterically hindered substrates
ME Due-Hansen, SK Pandey, E Christiansen, R Andersen, SVF Hansen, ...
Organic & Biomolecular Chemistry 14 (2), 430-433, 2016
1002016
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