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Baptiste Aussedat
Baptiste Aussedat
Chemitope Glycopeptide
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Staged induction of HIV-1 glycan–dependent broadly neutralizing antibodies
M Bonsignori, EF Kreider, D Fera, RR Meyerhoff, T Bradley, K Wiehe, ...
Science translational medicine 9 (381), eaai7514, 2017
1852017
An advance in the chemical synthesis of homogeneous N-linked glycopolypeptides by convergent aspartylation
P Wang, B Aussedat, Y Vohra, SJ Danishefsky
Angewandte Chemie (International ed. in English) 51 (46), 11571, 2012
1062012
Tracking a new cell-penetrating (W/R) nonapeptide, through an enzyme-stable mass spectrometry reporter tag
D Delaroche, B Aussedat, S Aubry, G Chassaing, F Burlina, G Clodic, ...
Analytical chemistry 79 (5), 1932-1938, 2007
1062007
Toward fully synthetic homogeneous β-human follicle-stimulating hormone (β-hFSH) with a biantennary N-linked dodecasaccharide. Synthesis of β-hFSH with chitobiose units at the …
P Nagorny, B Fasching, X Li, G Chen, B Aussedat, SJ Danishefsky
Journal of the American Chemical Society 131 (16), 5792-5799, 2009
1032009
Cell biology meets biophysics to unveil the different mechanisms of penetratin internalization in cells
ID Alves, CY Jiao, S Aubry, B Aussedat, F Burlina, G Chassaing, S Sagan
Biochimica et Biophysica Acta (BBA)-Biomembranes 1798 (12), 2231-2239, 2010
1012010
Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide
SM Alam, B Aussedat, Y Vohra, RR Meyerhoff, EM Cale, WE Walkowicz, ...
Science translational medicine 9 (381), eaai7521, 2017
902017
Recognition of synthetic glycopeptides by HIV-1 broadly neutralizing antibodies and their unmutated ancestors
SM Alam, SM Dennison, B Aussedat, Y Vohra, PK Park, ...
Proceedings of the National Academy of Sciences 110 (45), 18214-18219, 2013
902013
Chemical Synthesis of Highly Congested gp120 V1V2 N-Glycopeptide Antigens for Potential HIV-1-Directed Vaccines
B Aussedat, Y Vohra, PK Park, A Fernández-Tejada, SM Alam, ...
Journal of the American Chemical Society 135 (35), 13113-13120, 2013
762013
Vaccine elicitation of high mannose-dependent neutralizing antibodies against the V3-glycan broadly neutralizing epitope in nonhuman primates
KO Saunders, NI Nicely, K Wiehe, M Bonsignori, RR Meyerhoff, R Parks, ...
Cell reports 18 (9), 2175-2188, 2017
722017
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies
WB Williams, RR Meyerhoff, RJ Edwards, H Li, K Manne, NI Nicely, ...
Cell 184 (11), 2955-2972. e25, 2021
652021
Total synthesis of the α-subunit of human glycoprotein hormones: toward fully synthetic homogeneous human follicle-stimulating hormone
B Aussedat, B Fasching, E Johnston, N Sane, P Nagorny, SJ Danishefsky
Journal of the American Chemical Society 134 (7), 3532-3541, 2012
562012
MALDI-TOF mass spectrometry: A powerful tool to study the internalization of cell-penetrating peptides
S Aubry, B Aussedat, D Delaroche, CY Jiao, G Bolbach, S Lavielle, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1798 (12), 2182-2189, 2010
512010
Probing the frontiers of glycoprotein synthesis: the fully elaborated β-subunit of the human follicle-stimulating hormone
P Nagorny, N Sane, B Fasching, B Aussedat, SJ Danishefsky
Angewandte Chemie (International ed. in English) 51 (4), 975, 2012
502012
Quantification of the efficiency of cargo delivery by peptidic and pseudo-peptidic Trojan carriers using MALDI-TOF mass spectrometry
B Aussedat, S Sagan, G Chassaing, G Bolbach, F Burlina
Biochimica et Biophysica Acta (BBA)-Biomembranes 1758 (3), 375-383, 2006
462006
Star nanoparticles delivering HIV-1 peptide minimal immunogens elicit near-native envelope antibody responses in nonhuman primates
JR Francica, R Laga, GM Lynn, G Mužíková, L Androvič, B Aussedat, ...
PLoS biology 17 (6), e3000328, 2019
392019
HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope
D Fera, MS Lee, K Wiehe, RR Meyerhoff, A Piai, M Bonsignori, ...
Nature communications 9 (1), 1111, 2018
322018
Modifications in the chemical structure of Trojan carriers: impact on cargo delivery
B Aussedat, E Dupont, S Sagan, A Joliot, S Lavielle, G Chassaing, ...
Chemical communications, 1398-1400, 2008
222008
Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Sci Transl Med 9: eaai7514
M Bonsignori, EF Kreider, D Fera, RR Meyerhoff, T Bradley, K Wiehe, ...
152017
A Diels–Alder route to angularly functionalized bicyclic structures
WH Kim, JH Lee, B Aussedat, SJ Danishefsky
Tetrahedron 66 (33), 6391-6398, 2010
152010
‘Bis-ornithine’(2, 2-bis (aminopropyl) glycine): a new tetravalent template for assembling different functional peptides
B Aussedat, G Chassaing, S Lavielle, F Burlina
Tetrahedron letters 47 (22), 3723-3726, 2006
142006
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Artiklar 1–20