Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables E Ahlqvist, P Storm, A Käräjämäki, M Martinell, M Dorkhan, A Carlsson, ... The lancet Diabetes & endocrinology 6 (5), 361-369, 2018 | 2005 | 2018 |
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism J Fadista, P Vikman, EO Laakso, IG Mollet, JL Esguerra, J Taneera, ... Proceedings of the National Academy of Sciences 111 (38), 13924-13929, 2014 | 468 | 2014 |
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets J Taneera, S Lang, A Sharma, J Fadista, Y Zhou, E Ahlqvist, A Jonsson, ... Cell metabolism 16 (1), 122-134, 2012 | 407 | 2012 |
TCF7L2 is a master regulator of insulin production and processing Y Zhou, SY Park, J Su, K Bailey, E Ottosson-Laakso, L Shcherbina, ... Human molecular genetics 23 (24), 6419-6431, 2014 | 236 | 2014 |
Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD PK Luukkonen, Y Zhou, PAN Haridas, OP Dwivedi, T Hyötyläinen, A Ali, ... Journal of hepatology 67 (1), 128-136, 2017 | 128 | 2017 |
Gene expression and molecular changes in cerebral arteries following subarachnoid hemorrhage in the rat P Vikman, S Beg, T Khurana, J Hansen-Schwartz, L Edvinsson Journal of neurosurgery 105 (3), 438-444, 2006 | 113 | 2006 |
ERK1/2 Inhibition Attenuates Cerebral Blood Flow Reduction and Abolishes ETB and 5-HT1B Receptor Upregulation after Subarachnoid Hemorrhage in Rat SAS Beg, JA Hansen-Schwartz, PJ Vikman, CB Xu, LIH Edvinsson Journal of Cerebral Blood Flow & Metabolism 26 (6), 846-856, 2006 | 94 | 2006 |
Glucose-dependent granule docking limits insulin secretion and is decreased in human type 2 diabetes NR Gandasi, P Yin, M Omar-Hmeadi, EO Laakso, P Vikman, S Barg Cell metabolism 27 (2), 470-478. e4, 2018 | 93 | 2018 |
Glucose-induced changes in gene expression in human pancreatic islets: causes or consequences of chronic hyperglycemia E Ottosson-Laakso, U Krus, P Storm, RB Prasad, N Oskolkov, E Ahlqvist, ... Diabetes 66 (12), 3013-3028, 2017 | 81 | 2017 |
Serotonin (5-HT) receptor 2b activation augments glucose-stimulated insulin secretion in human and mouse islets of Langerhans H Bennet, IG Mollet, A Balhuizen, A Medina, C Nagorny, A Bagge, ... Diabetologia 59, 744-754, 2016 | 81 | 2016 |
Gene expression profiling in the human middle cerebral artery after cerebral ischemia P Vikman, L Edvinsson European journal of neurology 13 (12), 1324-1332, 2006 | 80 | 2006 |
Cerebral ischemia induces transcription of inflammatory and extracellular-matrix-related genes in rat cerebral arteries P Vikman, S Ansar, M Henriksson, E Stenman, L Edvinsson Experimental Brain Research 183, 499-510, 2007 | 75 | 2007 |
Cerebrovascular ETB, 5-HT1B, and AT1 receptor upregulation correlates with reduction in regional CBF after subarachnoid hemorrhage S Ansar, P Vikman, M Nielsen, L Edvinsson American Journal of Physiology-Heart and Circulatory Physiology 293 (6 …, 2007 | 71 | 2007 |
HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells M Daneshpajooh, K Bacos, M Bysani, A Bagge, E Ottosson Laakso, ... Diabetologia 60, 116-125, 2017 | 70 | 2017 |
MEK1/2 inhibition attenuates vascular ETA and ETB receptor alterations after cerebral ischaemia M Henriksson, E Stenman, P Vikman, L Edvinsson Experimental brain research 178, 470-476, 2007 | 69 | 2007 |
The complement inhibitor CD59 regulates insulin secretion by modulating exocytotic events U Krus, BC King, V Nagaraj, NR Gandasi, J Sjölander, P Buda, ... Cell metabolism 19 (5), 883-890, 2014 | 68 | 2014 |
Protein Kinase C Inhibition Prevents Upregulation of Vascular ETB and 5-HT1B Receptors and Reverses Cerebral Blood Flow Reduction after Subarachnoid … SS Beg, JA Hansen-Schwartz, PJ Vikman, CB Xu, LI Edvinsson Journal of Cerebral Blood Flow & Metabolism 27 (1), 21-32, 2007 | 50 | 2007 |
Transcriptional regulation of inflammatory and extracellular matrix–regulating genes in cerebral arteries following experimental subarachnoid hemorrhage in rats P Vikman, S Ansar, L Edvinsson Journal of neurosurgery 107 (5), 1015-1022, 2007 | 49 | 2007 |
Influence of Familial Renal Glycosuria Due to Mutations in the SLC5A2 Gene on Changes in Glucose Tolerance over Time E Ottosson-Laakso, T Tuomi, B Forsén, M Gullström, PH Groop, L Groop, ... PLoS One 11 (1), e0146114, 2016 | 31 | 2016 |
AUTHOR COPY ONLY P Vikman, J Fadista, N Oskolkov Endocrinology 53, R93-R101, 2014 | 30 | 2014 |