| Genome-wide profiling of PPARγ: RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during … R Nielsen, TÅ Pedersen, D Hagenbeek, P Moulos, R Siersbæk, ... Genes & development 22 (21), 2953-2967, 2008 | 583 | 2008 |
| PPARγ in adipocyte differentiation and metabolism–novel insights from genome-wide studies R Siersbæk, R Nielsen, S Mandrup FEBS letters 584 (15), 3242-3249, 2010 | 440 | 2010 |
| Extensive chromatin remodelling and establishment of transcription factor ‘hotspots’ during early adipogenesis R Siersbæk, R Nielsen, S John, MH Sung, S Baek, A Loft, GL Hager, ... The EMBO journal 30 (8), 1459-1472, 2011 | 373 | 2011 |
| Transcriptional networks and chromatin remodeling controlling adipogenesis R Siersbæk, R Nielsen, S Mandrup Trends in Endocrinology & Metabolism 23 (2), 56-64, 2012 | 298 | 2012 |
| Transcription factor cooperativity in early adipogenic hotspots and super-enhancers R Siersbæk, A Rabiee, R Nielsen, S Sidoli, S Traynor, A Loft, ... Cell reports 7 (5), 1443-1455, 2014 | 248 | 2014 |
| Peroxisome proliferator-activated receptor γ and C/EBPα synergistically activate key metabolic adipocyte genes by assisted loading MS Madsen, R Siersbæk, M Boergesen, R Nielsen, S Mandrup Molecular and cellular biology 34 (6), 939-954, 2014 | 235 | 2014 |
| Dynamic rewiring of promoter-anchored chromatin loops during adipocyte differentiation R Siersbæk, JGS Madsen, BM Javierre, R Nielsen, EK Bagge, J Cairns, ... Molecular cell 66 (3), 420-435. e5, 2017 | 205 | 2017 |
| IL6/STAT3 signaling hijacks estrogen receptor α enhancers to drive breast cancer metastasis R Siersbæk, V Scabia, S Nagarajan, I Chernukhin, EK Papachristou, ... Cancer cell 38 (3), 412-423. e9, 2020 | 168 | 2020 |
| Combined inhibition of mTOR and CDK4/6 is required for optimal blockade of E2F function and long-term growth inhibition in estrogen receptor–positive breast cancer C Michaloglou, C Crafter, R Siersbaek, O Delpuech, JO Curwen, ... Molecular cancer therapeutics 17 (5), 908-920, 2018 | 150 | 2018 |
| ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response S Nagarajan, SV Rao, J Sutton, D Cheeseman, S Dunn, EK Papachristou, ... Nature genetics 52 (2), 187-197, 2020 | 133 | 2020 |
| Signaling pathways and steroid receptors modulating estrogen receptor α function in breast cancer R Siersbæk, S Kumar, JS Carroll Genes & development 32 (17-18), 1141-1154, 2018 | 133 | 2018 |
| A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes EK Papachristou, K Kishore, AN Holding, K Harvey, TI Roumeliotis, ... Nature communications 9 (1), 2311, 2018 | 120 | 2018 |
| Molecular basis for gene-specific transactivation by nuclear receptors MM Aagaard, R Siersbæk, S Mandrup Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (8), 824-835, 2011 | 116 | 2011 |
| Molecular architecture of transcription factor hotspots in early adipogenesis R Siersbæk, S Baek, A Rabiee, R Nielsen, S Traynor, N Clark, A Sandelin, ... Cell reports 7 (5), 1434-1442, 2014 | 69 | 2014 |
| CD1d-mediated presentation of endogenous lipid antigens by adipocytes requires microsomal triglyceride transfer protein M Rakhshandehroo, SMW Gijzel, R Siersbæk, MF Broekema, C de Haar, ... Journal of Biological Chemistry 289 (32), 22128-22139, 2014 | 34 | 2014 |
| TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions R Broome, I Chernukhin, S Jamieson, K Kishore, EK Papachristou, ... Cell reports 34 (8), 2021 | 25 | 2021 |
| Identification of ChIP-seq and RIME grade antibodies for Estrogen Receptor alpha SE Glont, EK Papachristou, A Sawle, KA Holmes, JS Carroll, R Siersbaek PLoS One 14 (4), e0215340, 2019 | 12 | 2019 |
| Hierarchical role for transcription factors and chromatin structure in genome organization along adipogenesis A Sarusi Portuguez, M Schwartz, R Siersbaek, R Nielsen, MH Sung, ... The FEBS journal 284 (19), 3230-3244, 2017 | 11 | 2017 |
| Propionate reinforces epithelial identity and reduces aggressiveness of lung carcinoma V Ramesh, PN Gollavilli, L Pinna, MA Siddiqui, AM Turtos, F Napoli, ... EMBO Molecular Medicine 15 (12), e17836, 2023 | 2 | 2023 |
| MYC activity at enhancers drives prognostic transcriptional programs through an epigenetic switch ST Jakobsen, RAM Jensen, MS Madsen, T Ravnsborg, CS Vaagenso, ... Nature Genetics, 1-12, 2024 | 1 | 2024 |
