Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases MT Lin, MF Beal Nature 443 (7113), 787-795, 2006 | 7198 | 2006 |
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease S Kriks, JW Shim, J Piao, YM Ganat, DR Wakeman, Z Xie, L Carrillo-Reid, ... Nature 480 (7378), 547-551, 2011 | 2141 | 2011 |
Aging, energy, and oxidative stress in neurodegenerative diseases MF Beal Annals of neurology 38 (3), 357-366, 1995 | 1881 | 1995 |
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury AG Reaume, JL Elliott, EK Hoffman, NW Kowall, RJ Ferrante, DR Siwek, ... Nature genetics 13 (1), 43-47, 1996 | 1681 | 1996 |
Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid MF Beal, NW Kowall, DW Ellison, MF Mazurek, KJ Swartz, JB Martin Nature 321 (6066), 168-171, 1986 | 1551 | 1986 |
Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease P Mecocci, U MacGarvey, MF Beal Annals of Neurology: Official Journal of the American Neurological …, 1994 | 1468 | 1994 |
Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline CW Shults, D Oakes, K Kieburtz, MF Beal, R Haas, S Plumb, JL Juncos, ... Archives of neurology 59 (10), 1541-1550, 2002 | 1452 | 2002 |
Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? MF Beal Annals of Neurology: Official Journal of the American Neurological …, 1992 | 1297 | 1992 |
Oxidative damage in Alzheimer's MA Smith, G Perry, PL Richey, LM Sayrec, VE Anderson, MF Beal, ... Nature 382 (6587), 120-121, 1996 | 1256 | 1996 |
Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid MF Beal, E Brouillet, BG Jenkins, RJ Ferrante, NW Kowall, JM Miller, ... Journal of Neuroscience 13 (10), 4181-4192, 1993 | 1228 | 1993 |
Parkinson's disease B Thomas, MF Beal Human molecular genetics 16 (R2), R183-R194, 2007 | 1182 | 2007 |
Mitochondria take center stage in aging and neurodegeneration MF Beal Annals of Neurology: Official Journal of the American Neurological …, 2005 | 1151 | 2005 |
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease PH Reddy, MF Beal Trends in molecular medicine 14 (2), 45-53, 2008 | 1126 | 2008 |
Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age M Corral-Debrinski, T Horton, MT Lott, JM Shoffner, M Flint Beal, ... Nature genetics 2 (4), 324-329, 1992 | 1090 | 1992 |
Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia SE Browne, AC Bowling, U Macgarvey, MJ Baik, SC Berger, MMK Muquit, ... Annals of Neurology: Official Journal of the American Neurological …, 1997 | 1089 | 1997 |
Oxidatively modified proteins in aging and disease MF Beal Free Radical Biology and Medicine 32 (9), 797-803, 2002 | 1058 | 2002 |
Intensive immunosuppression in progressive multiple sclerosis: a randomized, three-arm study of high-dose intravenous cyclophosphamide, plasma exchange, and ACTH SL Hauser, DM Dawson, JR Lehrich, MF Beal, SV Kevy, RD Propper, ... New England Journal of Medicine 308 (4), 173-180, 1983 | 1019 | 1983 |
Oxidative damage to mitochondrial DNA shows marked age‐dependent increases in human brain P Mecocci, U MacGarvey, AE Kaufman, D Koontz, JM Shoffner, ... Annals of Neurology: Official Journal of the American Neurological …, 1993 | 1008 | 1993 |
Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis RJ Ferrante, SE Browne, LA Shinobu, AC Bowling, MJ Baik, U MacGarvey, ... Journal of neurochemistry 69 (5), 2064-2074, 1997 | 993 | 1997 |
Functional engraftment of human ES cell–derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes NS Roy, C Cleren, SK Singh, L Yang, MF Beal, SA Goldman Nature medicine 12 (11), 1259-1268, 2006 | 981 | 2006 |