Stephan Schürer
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Crystal structure of a lipid G protein–coupled receptor
MA Hanson, CB Roth, E Jo, MT Griffith, FL Scott, G Reinhart, H Desale, ...
Science 335 (6070), 851-855, 2012
6682012
Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation
JH Choi, AS Banks, TM Kamenecka, SA Busby, MJ Chalmers, N Kumar, ...
Nature 477 (7365), 477-481, 2011
4872011
Suppression of TH 17 differentiation and autoimmunity by a synthetic ROR ligand
LA Solt, N Kumar, P Nuhant, Y Wang, JL Lauer, J Liu, MA Istrate, ...
Nature 472 (7344), 491-494, 2011
4732011
Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress
R Ghosh, L Wang, ES Wang, BGK Perera, A Igbaria, S Morita, K Prado, ...
Cell 158 (3), 534-548, 2014
3212014
Synthesis and Application of a Permanently Immobilized Olefin‐Metathesis Catalyst
SC Schürer, S Gessler, N Buschmann, S Blechert
Angewandte Chemie International Edition 39 (21), 3898-3901, 2000
2502000
The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations
AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ...
Cell systems 6 (1), 13-24, 2018
2042018
Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors
L Wang, BGK Perera, SB Hari, B Bhhatarai, BJ Backes, MA Seeliger, ...
Nature chemical biology 8 (12), 982-989, 2012
1742012
Unexplored therapeutic opportunities in the human genome
TI Oprea, CG Bologa, S Brunak, A Campbell, GN Gan, A Gaulton, ...
Nature reviews Drug discovery 17 (5), 317, 2018
1672018
Pharos: collating protein information to shed light on the druggable genome
DT Nguyen, S Mathias, C Bologa, S Brunak, N Fernandez, A Gaulton, ...
Nucleic acids research 45 (D1), D995-D1002, 2017
1392017
BioAssay Ontology (BAO): a semantic description of bioassays and high-throughput screening results
U Visser, S Abeyruwan, U Vempati, RP Smith, V Lemmon, SC Schürer
BMC bioinformatics 12 (1), 1-16, 2011
1102011
Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors
DA Bachovchin, JT Mohr, AE Speers, C Wang, JM Berlin, TP Spicer, ...
Proceedings of the National Academy of Sciences 108 (17), 6811-6816, 2011
1092011
FAIRsharing as a community approach to standards, repositories and policies
SA Sansone, P McQuilton, P Rocca-Serra, A Gonzalez-Beltran, M Izzo, ...
Nature biotechnology 37 (4), 358-367, 2019
1052019
Small molecule–mediated activation of the integrin CD11b/CD18 reduces inflammatory disease
D Maiguel, MH Faridi, C Wei, Y Kuwano, KM Balla, D Hernandez, ...
Science signaling 4 (189), ra57-ra57, 2011
982011
Expedient solid-phase synthesis of putative β-turn mimetics incorporating the i+ 1, i+ 2, and i+ 3 sidechains
AA Virgilio, SC Schürer, JA Ellman
Tetrahedron letters 37 (39), 6961-6964, 1996
961996
Synthese und Anwendung eines permanent immobilisierten Olefinmetathese‐Katalysators
SC Schürer, S Gessler, N Buschmann, S Blechert
Angewandte Chemie 112 (21), 4062-4065, 2000
862000
Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data
A Koleti, R Terryn, V Stathias, C Chung, DJ Cooper, JP Turner, D Vidović, ...
Nucleic acids research 46 (D1), D558-D566, 2018
822018
Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors
Y Feng, Y Yin, A Weiser, E Griffin, MD Cameron, L Lin, C Ruiz, ...
Journal of medicinal chemistry 51 (21), 6642-6645, 2008
802008
Benzimidazole-and benzoxazole-based inhibitors of Rho kinase
EH Sessions, Y Yin, TD Bannister, A Weiser, E Griffin, J Pocas, ...
Bioorganic & medicinal chemistry letters 18 (24), 6390-6393, 2008
782008
A versatile synthesis of substituted tetrahydropyridines
SC Schürer, S Blechert
Tetrahedron letters 40 (10), 1877-1880, 1999
761999
CLO: the cell line ontology
S Sarntivijai, Y Lin, Z Xiang, TF Meehan, AD Diehl, UD Vempati, ...
Journal of biomedical semantics 5 (1), 1-10, 2014
732014
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Artiklar 1–20