| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13152* | 2021 |
| Inflammation and metabolic disorders GS Hotamisligil Nature 444 (7121), 860-867, 2006 | 10315 | 2006 |
| Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance GS Hotamisligil, NS Shargill, BM Spiegelman Science 259 (5091), 87-91, 1993 | 10151 | 1993 |
| Inflammation, stress, and diabetes KE Wellen, GS Hotamisligil The Journal of clinical investigation 115 (5), 1111-1119, 2005 | 5662 | 2005 |
| Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. GS Hotamisligil, P Arner, JF Caro, RL Atkinson, BM Spiegelman The Journal of clinical investigation 95 (5), 2409-2415, 1995 | 4889 | 1995 |
| Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes U Ozcan, Q Cao, E Yilmaz, AH Lee, NN Iwakoshi, E Ozdelen, G Tuncman, ... Science 306 (5695), 457-461, 2004 | 4553 | 2004 |
| Inflammatory mechanisms in obesity MF Gregor, GS Hotamisligil Annual review of immunology 29, 415-445, 2011 | 4372 | 2011 |
| A central role for JNK in obesity and insulin resistance J Hirosumi, G Tuncman, L Chang, CZ Görgün, KT Uysal, K Maeda, ... Nature 420 (6913), 333-336, 2002 | 4161 | 2002 |
| IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α-and obesity-induced insulin resistance GS Hotamisligil, P Peraldi, A Budavari, R Ellis, MF White, BM Spiegelman Science 271 (5249), 665-670, 1996 | 3677 | 1996 |
| Endoplasmic reticulum stress and the inflammatory basis of metabolic disease GS Hotamisligil Cell 140 (6), 900-917, 2010 | 3108 | 2010 |
| Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes U Ozcan, E Yilmaz, L Ozcan, M Furuhashi, E Vaillancourt, RO Smith, ... Science 313 (5790), 1137-1140, 2006 | 2789 | 2006 |
| Obesity-induced inflammatory changes in adipose tissue KE Wellen, GS Hotamisligil The Journal of clinical investigation 112 (12), 1785-1788, 2003 | 2465 | 2003 |
| Plasma adiponectin levels and risk of myocardial infarction in men T Pischon, CJ Girman, GS Hotamisligil, N Rifai, FB Hu, EB Rimm Jama 291 (14), 1730-1737, 2004 | 2424 | 2004 |
| Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth KM Nieman, HA Kenny, CV Penicka, A Ladanyi, R Buell-Gutbrod, ... Nature medicine 17 (11), 1498-1503, 2011 | 2196 | 2011 |
| Tumor necrosis factor α: a key component of the obesity-diabetes link GS Hotamisligil, BM Spiegelman Diabetes 43 (11), 1271-1278, 1994 | 1978 | 1994 |
| Inflammation, metaflammation and immunometabolic disorders GS Hotamisligil Nature 542 (7640), 177-185, 2017 | 1849 | 2017 |
| Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets M Furuhashi, GS Hotamisligil Nature reviews Drug discovery 7 (6), 489-503, 2008 | 1813 | 2008 |
| Tumor necrosis factor alpha inhibits signaling from the insulin receptor. GS Hotamisligil, DL Murray, LN Choy, BM Spiegelman Proceedings of the National Academy of Sciences 91 (11), 4854-4858, 1994 | 1653 | 1994 |
| Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance L Yang, P Li, S Fu, ES Calay, GS Hotamisligil Cell metabolism 11 (6), 467-478, 2010 | 1366 | 2010 |
| Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism H Cao, K Gerhold, JR Mayers, MM Wiest, SM Watkins, GS Hotamisligil Cell 134 (6), 933-944, 2008 | 1265 | 2008 |
