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Xaria X. Li
Xaria X. Li
Postdoctoral researcher, The University of Queensland
Verifierad e-postadress på uq.edu.au - Startsida
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The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 178, S27-S156, 2021
4452021
The complement receptor C5aR2: a powerful modulator of innate and adaptive immunity
XX Li, JD Lee, C Kemper, TM Woodruff
The Journal of Immunology 202 (12), 3339-3348, 2019
1162019
New concepts on the therapeutic control of complement anaphylatoxin receptors
OA Hawksworth, XX Li, LG Coulthard, EJ Wolvetang, TM Woodruff
Molecular immunology 89, 36-43, 2017
802017
Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2
FH Brennan, T Jogia, ER Gillespie, LV Blomster, XX Li, B Nowlan, ...
JCI insight 4 (9), 2019
792019
SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein
EA Albornoz, AA Amarilla, N Modhiran, S Parker, XX Li, DK Wijesundara, ...
Molecular psychiatry 28 (7), 2878-2893, 2023
742023
Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors
S Pandey, P Kumari, M Baidya, R Kise, Y Cao, H Dwivedi-Agnihotri, ...
Molecular cell 81 (22), 4605-4621. e11, 2021
722021
Emerging insights into the structure and function of complement C5a receptors
S Pandey, J Maharana, XX Li, TM Woodruff, AK Shukla
Trends in biochemical sciences 45 (8), 693-705, 2020
652020
Pharmacological characterisation of small molecule C5aR1 inhibitors in human cells reveals biased activities for signalling and function
XX Li, JD Lee, NL Massey, C Guan, AAB Robertson, RJ Clark, ...
Biochemical pharmacology 180, 114156, 2020
512020
C5aR2 activation broadly modulates the signaling and function of primary human macrophages
XX Li, RJ Clark, TM Woodruff
The Journal of Immunology 205 (4), 1102-1112, 2020
422020
Partial ligand-receptor engagement yields functional bias at the human complement receptor, C5aR1
S Pandey, XX Li, A Srivastava, M Baidya, P Kumari, H Dwivedi, ...
Journal of Biological Chemistry 294 (24), 9416-9429, 2019
342019
C5a receptors C5aR1 and C5aR2 mediate opposing pathologies in a mouse model of melanoma
JA Nabizadeh, HD Manthey, N Panagides, FJ Steyn, JD Lee, XX Li, ...
The FASEB Journal 33 (10), 11060-11071, 2019
262019
The “C3aR antagonist” SB290157 is a partial C5aR2 agonist
XX Li, V Kumar, RJ Clark, JD Lee, TM Woodruff
Frontiers in Pharmacology 11, 591398, 2021
242021
Development of potent and selective agonists for complement C5a receptor 1 with in vivo activity
DM Gorman, XX Li, JD Lee, JN Fung, CS Cui, HS Lee, BE Rolfe, ...
Journal of Medicinal Chemistry 64 (22), 16598-16608, 2021
92021
Anaphylatoxin receptor promiscuity for commonly used complement C5a peptide agonists
XX Li, RJ Clark, TM Woodruff
International Immunopharmacology 100, 108074, 2021
72021
Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors
MK Yadav, J Maharana, R Yadav, S Saha, P Sarma, C Soni, V Singh, ...
Cell 186 (22), 4956-4973. e21, 2023
52023
Development of Synthetic Human and Mouse C5a: Application to Binding and Functional Assays In Vitro and In Vivo
DM Gorman, XX Li, CD Payne, CS Cui, JD Lee, KJ Rosengren, ...
ACS Pharmacology & Translational Science 4 (6), 1808-1817, 2021
42021
Optimisation of a Microfluidic Method for the Delivery of a Small Peptide
FY Han, W Xu, V Kumar, CS Cui, X Li, X Jiang, TM Woodruff, AK Whittaker, ...
Pharmaceutics 13 (9), 1505, 2021
32021
TLQP-21 is a low potency partial C3aR activator on human primary macrophages
XX Li, JD Lee, HS Lee, RJ Clark, TM Woodruff
Frontiers in Immunology 14, 1086673, 2023
22023
Unexpected off-target activities for recombinant C5a in human macrophages
XX Li, DM Gorman, JD Lee, RJ Clark, TM Woodruff
The Journal of Immunology 208 (1), 133-142, 2022
22022
Protocol for cell-based screening assay to measure ERK1/2 phosphorylation as a readout for complement receptor activation
XX Li, TM Woodruff
STAR protocols 4 (4), 102758, 2023
12023
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Artiklar 1–20