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zhonghui lin
zhonghui lin
Verified email at utsouthwestern.edu
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Year
Structural basis for recognition of urokinase-type plasminogen activator by plasminogen activator inhibitor-1
Z Lin, L Jiang, C Yuan, JK Jensen, X Zhang, Z Luo, BC Furie, B Furie, ...
Journal of biological chemistry 286 (9), 7027-7032, 2011
712011
Oleanolic acid derivative NPLC441 potently stimulates glucose transport in 3T3-L1 adipocytes via a multi-target mechanism
Z Lin, Y Zhang, Y Zhang, H Shen, L Hu, H Jiang, X Shen
Biochemical pharmacology 76 (10), 1251-1262, 2008
522008
Structural basis for therapeutic intervention of uPA/uPAR system
J Chi Ki Ngo, L Jiang, Z Lin, C Yuan, Z Chen, X Zhang, H Yu, J Wang, ...
Current drug targets 12 (12), 1729-1743, 2011
492011
Structural insight into inactivation of plasminogen activator inhibitor-1 by a small-molecule antagonist
Z Lin, JK Jensen, Z Hong, X Shi, L Hu, PA Andreasen, M Huang
Chemistry & biology 20 (2), 253-261, 2013
472013
Danshen extract 15, 16-dihydrotanshinone I functions as a potential modulator against metabolic syndrome through multi-target pathways
Q Liu, Y Zhang, Z Lin, H Shen, L Chen, L Hu, H Jiang, X Shen
The Journal of steroid biochemistry and molecular biology 120 (4-5), 155-163, 2010
382010
Substrate-specific activation of the mitotic kinase Bub1 through intramolecular autophosphorylation and kinetochore targeting
Z Lin, L Jia, DR Tomchick, X Luo, H Yu
Structure 22 (11), 1616-1627, 2014
312014
A specific plasminogen activator inhibitor‐1 antagonist derived from inactivated urokinase
L Gong, V Proulle, C Fang, Z Hong, Z Lin, M Liu, G Xue, C Yuan, L Lin, ...
Journal of cellular and molecular medicine 20 (10), 1851-1860, 2016
292016
Structural basis of sequence-specific Holliday junction cleavage by MOC1
H Lin, D Zhang, K Zuo, C Yuan, J Li, M Huang, Z Lin
Nature chemical biology 15 (12), 1241-1248, 2019
202019
Punicalagin as an allosteric NSP13 helicase inhibitor potently suppresses SARS-CoV-2 replication in vitro
L Lu, Y Peng, H Yao, Y Wang, J Li, Y Yang, Z Lin
Antiviral Research 206, 105389, 2022
192022
A hypoxia-activated prodrug conjugated with a BODIPY-based photothermal agent for imaging-guided chemo-photothermal combination therapy
DC Yang, LF Wen, L Du, CM Luo, ZY Lu, JY Liu, Z Lin
ACS Applied Materials & Interfaces 14 (36), 40546-40558, 2022
192022
Design, synthesis, and SAR of embelin analogues as the inhibitors of PAI-1 (plasminogen activator inhibitor-1)
F Chen, G Zhang, Z Hong, Z Lin, M Lei, M Huang, L Hu
Bioorganic & Medicinal Chemistry Letters 24 (10), 2379-2382, 2014
152014
Singlet oxygen-responsive polymeric nanomedicine for light-controlled drug release and image-guided photodynamic–chemo combination therapy
DC Yang, S Wang, XL Weng, HX Zhang, JY Liu, Z Lin
ACS Applied Materials & Interfaces 13 (29), 33905-33914, 2021
142021
Discovery of a novel Aurora B inhibitor GSK650394 with potent anticancer and anti-aspergillus fumigatus dual efficacies in vitro
Y He, W Fu, L Du, H Yao, Z Hua, J Li, Z Lin
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 109-117, 2022
102022
A promising strategy for synergistic cancer therapy by integrating a photosensitizer into a hypoxia-activated prodrug
DC Yang, XZ Yang, CM Luo, LF Wen, JY Liu, Z Lin
European Journal of Medicinal Chemistry 243, 114749, 2022
92022
Marine natural product des-O-methyllasiodiplodin effectively lowers the blood glucose level in db/db mice via ameliorating inflammation
R Zhou, Z Lin, C Jiang, J Gong, L Chen, Y Guo, X Shen
Acta Pharmacologica Sinica 34 (10), 1325-1336, 2013
72013
Crystal structure of the human MUS81-EME2 complex
Z Hua, Q Fang, D Zhang, Z Luo, C Yuan, Z Lin
Structure 30 (5), 743-752. e3, 2022
42022
Biochemical and structural characterization of the Holliday junction resolvase RuvC from Pseudomonas aeruginosa
Y Hu, Y He, Z Lin
Biochemical and Biophysical Research Communications 525 (2), 265-271, 2020
42020
Identification of small-molecule inhibitors of the DNA repair proteins RuvAB from Pseudomonas aeruginosa
L Dai, L Lu, X Zhang, J Wu, J Li, Z Lin
Bioorganic & Medicinal Chemistry 73, 117022, 2022
32022
Identification of small-molecule inhibitors of human MUS81-EME1/2 by FRET-based high-throughput screening
X Zhang, X Chen, L Lu, Q Fang, C Liu, Z Lin
Bioorganic & Medicinal Chemistry 90, 117383, 2023
22023
Cryo-EM structure of the RuvAB-Holliday junction intermediate complex from Pseudomonas aeruginosa
X Zhang, Z Zhou, L Dai, Y Chao, Z Liu, M Huang, Q Qu, Z Lin
Frontiers in Plant Science 14, 1139106, 2023
22023
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