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Jessica Neisen
Jessica Neisen
Verifierad e-postadress på astrazeneca.com
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Potentiation of inflammatory CXCL8 signalling sustains cell survival in PTEN-deficient prostate carcinoma
PJ Maxwell, J Coulter, SM Walker, M McKechnie, J Neisen, N McCabe, ...
European urology 64 (2), 177-188, 2013
952013
CD44 enhances invasion of basal-like breast cancer cells by upregulating serine protease and collagen-degrading enzymatic expression and activity
N Montgomery, A Hill, S McFarlane, J Neisen, A O'Grady, S Conlon, ...
Breast Cancer Research 14, 1-19, 2012
902012
Tumor-derived CXCL8 signaling augments stroma-derived CCL2-promoted proliferation and CXCL12-mediated invasion of PTEN-deficient prostate cancer cells
PJ Maxwell, J Neisen, J Messenger, DJJ Waugh
Oncotarget 5 (13), 4895, 2014
862014
Ex vivo expansion of human outgrowth endothelial cells leads to IL-8-mediated replicative senescence and impaired vasoreparative function
RJ Medina, CL O'neill, TM O'Doherty, SEJ Chambers, J Guduric-Fuchs, ...
Stem Cells 31 (8), 1657-1668, 2013
752013
PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy
CWD Armstrong, PJ Maxwell, CW Ong, KM Redmond, C McCann, ...
Oncotarget 7 (7), 7885, 2016
372016
A randomized trial of otilimab in severe COVID-19 pneumonia (OSCAR)
J Patel, A Beishuizen, XB Ruiz, H Boughanmi, A Cahn, GJ Criner, K Davy, ...
medRxiv, 2021.04. 14.21255475, 2021
282021
Patient-reported wellbeing and clinical disease measures over time captured by multivariate trajectories of disease activity in individuals with juvenile idiopathic arthritis …
SJW Shoop-Worrall, KL Hyrich, LR Wedderburn, W Thomson, N Geifman, ...
The Lancet Rheumatology 3 (2), e111-e121, 2021
252021
A randomised trial of anti-GM-CSF otilimab in severe COVID-19 pneumonia (OSCAR)
J Patel, D Bass, A Beishuizen, XB Ruiz, H Boughanmi, A Cahn, ...
European Respiratory Journal 61 (2), 2023
172023
Mathematical modelling of alternative pathway of complement system
S Bakshi, F Cunningham, EM Nichols, M Biedzka-Sarek, J Neisen, ...
Bulletin of mathematical biology 82, 1-32, 2020
112020
Mathematical Modeling of Complement Pathway Dynamics for Target Validation and Selection of Drug Modalities for Complement Therapies
L Bansal, EM Nichols, DP Howsmon, J Neisen, CM Bessant, ...
Frontiers in Pharmacology, 2022
52022
Interpretable histopathology-based prediction of disease relevant features in Inflammatory Bowel Disease biopsies using weakly-supervised deep learning
R Mokhtari, A Hamidinekoo, D Sutton, A Lewis, B Angermann, ...
arXiv preprint arXiv:2303.12095, 2023
32023
Development and application of a Quantitative Systems Pharmacology (QSP) model of complement pathway to evaluate treatments for autoimmune diseases
L Bansal, J Neisen, EM Nichols, V Damian
J. Pharmacokinet Pharmacodyn 44, S91-S92, 2017
22017
Abstract A49: Cabozantinib attenuates CXCL8-driven macrophage-dependent migration and invasion of PTEN-deficient prostate cancer
JL Neisen, N McCabe, RD Kennedy, DJJ Waugh
Cancer Research 75 (1_Supplement), A49-A49, 2015
22015
DOP06 deep characterization of IL-23 pathway in different gut segments and associated plasma biomarkers in inflammatory bowel disease
J Cairns, S Monkley, S Tian, B Angermann, Z Liu, L Öberg, D Muthas, ...
Journal of Crohn's and Colitis 17 (Supplement_1), i64-i67, 2023
12023
P879 Clinical significance of plasma interleukin-22 as a biomarker of inflammation in patients with Crohn’s disease and ulcerative colitis
C Cabrera-Moksnes, D Fernandez-Llaneza, J Neisen, BR Angermann, ...
Journal of Crohn's and Colitis 17 (Supplement_1), i996-i997, 2023
12023
IL-7 Binding Proteins and Their Use in Medical Therapy
G Bouma, ET Coulstock, D Dixon, S Hopley, AP Lewis, JL Neisen
US Patent App. 18/460,944, 2024
2024
Artificial Intelligence to predict interleukin-23 signalling activity from H&E stained whole slide images of Inflammatory Bowel Disease
T Qaiser, A Hamidinekoo, S Daniel, I Zhang, M Kekic, A Lewis, ...
JOURNAL OF CROHNS & COLITIS 18, I453-I453, 2024
2024
P153 Artificial Intelligence to predict interleukin-23 signalling activity from H&E stained whole slide images of Inflammatory Bowel Disease
T Qaiser, A Hamidinekoo, S Daniel, I Zhang, M Kekic, A Lewis, ...
Journal of Crohn's and Colitis 18 (Supplement_1), i458-i458, 2024
2024
Long-term safety of brazikumab in the open-label period of a randomized phase 2a study of patients with Crohn’s disease
S Danese, A Beaton, EA Duncan, AK Mercier, J Neisen, H Seth, ...
BMC gastroenterology 23 (1), 451, 2023
2023
IL-7 binding proteins and their use in medical therapy
G Bouma, ET Coulstock, D Dixon, S Hopley, AP Lewis, JL Neisen
US Patent 11,802,150, 2023
2023
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