| Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains Y Su, WRG Dostmann, FW Herberg, K Durick, NH Xuong, L Ten Eyck, ... Science 269 (5225), 807-813, 1995 | 477 | 1995 |
| Modulation of α-thrombin function by distinct interactions with platelet glycoprotein Ibα R Celikel, RA McClintock, JR Roberts, GL Mendolicchio, J Ware, ... Science 301 (5630), 218-221, 2003 | 236 | 2003 |
| Keeping signals straight in phosphorelay signal transduction JA Hoch, KI Varughese Journal of bacteriology 183 (17), 4941-4949, 2001 | 210 | 2001 |
| Crystal structure of a papain-E-64 complex KI Varughese, FR Ahmed, PR Carey, S Hasnain, CP Huber, AC Storer Biochemistry 28 (3), 1330-1332, 1989 | 210 | 1989 |
| Crystal structure of rat liver dihydropteridine reductase. KI Varughese, MM Skinner, JM Whiteley, DA Matthews, NH Xuong Proceedings of the National Academy of Sciences 89 (13), 6080-6084, 1992 | 209 | 1992 |
| A transient interaction between two phosphorelay proteins trapped in a crystal lattice reveals the mechanism of molecular recognition and phosphotransfer in signal transduction J Zapf, U Sen, JA Hoch, KI Varughese Structure 8 (8), 851-862, 2000 | 182 | 2000 |
| LOX-1 in atherosclerosis and myocardial ischemia: biology, genetics, and modulation NVK Pothineni, SK Karathanasis, Z Ding, A Arulandu, KI Varughese, ... Journal of the American College of Cardiology 69 (22), 2759-2768, 2017 | 165 | 2017 |
| Formation of a novel four-helix bundle and molecular recognition sites by dimerization of a response regulator phosphotransferase KI Varughese, XZ Zhou, JM Whiteley, JA Hoch Molecular cell 2 (4), 485-493, 1998 | 124 | 1998 |
| Crystal structure of the von Willebrand factor A1 domain in complex with the function blocking NMC-4 Fab R Celikel, KI Varughese, Madhusudan, A Yoshioka, J Ware, ZM Ruggeri Nature structural biology 5 (3), 189-194, 1998 | 123 | 1998 |
| Interactions between the YycFG and PhoPR two‐component systems in Bacillus subtilis: the PhoR kinase phosphorylates the non‐cognate YycF response … A Howell, S Dubrac, D Noone, KI Varughese, K Devine Molecular microbiology 59 (4), 1199-1215, 2006 | 110 | 2006 |
| Crystal structure of an actinidin-E-64 complex KI Varughese, Y Su, D Cromwell, S Hasnain, NH Xuong Biochemistry 31 (22), 5172-5176, 1992 | 98 | 1992 |
| von Willebrand factor conformation and adhesive function is modulated by an internalized water molecule R Celikel, ZM Ruggeri, KI Varughese Nature structural biology 7 (10), 881-884, 2000 | 92 | 2000 |
| Structural and mechanistic characteristics of dihydropteridine reductase: a member of the Tyr-(Xaa) 3-Lys-containing family of reductases and dehydrogenases. KI Varughese, NH Xuong, PM Kiefer, DA Matthews, JM Whiteley Proceedings of the National Academy of Sciences 91 (12), 5582-5586, 1994 | 90 | 1994 |
| DNA complexed structure of the key transcription factor initiating development in sporulating bacteria H Zhao, T Msadek, J Zapf, JA Hoch, KI Varughese Structure 10 (8), 1041-1050, 2002 | 78 | 2002 |
| Platelet dysfunction and a high bone mass phenotype in a murine model of platelet-type von Willebrand disease LJ Suva, E Hartman, JD Dilley, S Russell, NS Akel, RA Skinner, ... The American journal of pathology 172 (2), 430-439, 2008 | 77 | 2008 |
| The crystal structure of beryllofluoride Spo0F in complex with the phosphotransferase Spo0B represents a phosphotransfer pretransition state KI Varughese, I Tsigelny, H Zhao Journal of bacteriology 188 (13), 4970-4977, 2006 | 77 | 2006 |
| Crystal structure of the von Willebrand factor modulator botrocetin U Sen, S Vasudevan, G Subbarao, RA McClintock, R Celikel, ZM Ruggeri, ... Biochemistry 40 (2), 345-352, 2001 | 72 | 2001 |
| Molecular recognition of bacterial phosphorelay proteins KI Varughese Current opinion in microbiology 5 (2), 142-148, 2002 | 69 | 2002 |
| A source of response regulator autophosphatase activity: the critical role of a residue adjacent to the Spo0F autophosphorylation active site J Zapf, Madhusudan, CE Grimshaw, JA Hoch, KI Varughese, JM Whiteley Biochemistry 37 (21), 7725-7732, 1998 | 69 | 1998 |
| PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis T Fujiwara, S Ye, T Castro-Gomes, CG Winchell, NW Andrews, DE Voth, ... JCI insight 1 (17), 2016 | 68 | 2016 |
