| Identification in Haloferax volcanii of Phosphomevalonate Decarboxylase and Isopentenyl Phosphate Kinase as Catalysts of the Terminal Enzyme Reactions in an Archaeal Alternate … JC VanNice, DA Skaff, A Keightley, JK Addo, GJ Wyckoff, HM Miziorko Journal of bacteriology 196 (5), 1055-1063, 2014 | 78 | 2014 |
| Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis ML Barta, DA Skaff, WJ McWhorter, TJ Herdendorf, HM Miziorko, ... Journal of Biological Chemistry 286 (27), 23900-23910, 2011 | 40 | 2011 |
| Biochemical and Structural Basis for Inhibition of Enterococcus faecalis Hydroxymethylglutaryl-CoA Synthase, mvaS, by Hymeglusin DA Skaff, KX Ramyar, WJ McWhorter, ML Barta, BV Geisbrecht, ... Biochemistry 51 (23), 4713-4722, 2012 | 35 | 2012 |
| A visible wavelength spectrophotometric assay suitable for high-throughput screening of 3-hydroxy-3-methylglutaryl-CoA synthase D Andrew Skaff, HM Miziorko Analytical biochemistry 396 (1), 96-102, 2010 | 34 | 2010 |
| Glucose 6-phosphate release of wild-type and mutant human brain hexokinases from mitochondria DA Skaff, CS Kim, HJ Tsai, RB Honzatko, HJ Fromm Journal of Biological Chemistry 280 (46), 38403-38409, 2005 | 31 | 2005 |
| Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase LF Peng, EAK Schaefer, N Maloof, A Skaff, A Berical, CA Belon, JA Heck, ... Journal of Infectious Diseases 204 (4), 609-616, 2011 | 17 | 2011 |
| Expression in Haloferax volcanii of 3-Hydroxy-3-methylglutaryl-CoA synthase Facilitates Isolation and Characterization of the Active Form of a Key Enzyme Required for … J VanNice, DA Skaff, GJ Wyckoff, HM Miziorko Journal of Bacteriology, 2013 | 11 | 2013 |
| Active site binding modes of inhibitors of Staphylococcus aureus mevalonate diphosphate decarboxylase from docking and molecular dynamics simulations JK Addo, DA Skaff, HM Miziorko Journal of molecular modeling 22 (1), 1-18, 2016 | 5 | 2016 |
| Inhibition of bacterial mevalonate diphosphate decarboxylase by eriochrome compounds DA Skaff, WJ McWhorter, BV Geisbrecht, GJ Wyckoff, HM Miziorko Archives of biochemistry and biophysics 566, 1-6, 2015 | 5 | 2015 |
| Big Data and Drug Discovery GJ Wyckoff, DA Skaff Big Data Analysis for Bioinformatics and Biomedical Discoveries, 215-231, 2015 | 1* | 2015 |
| Inhibition of S. epidermidis mevalonate diphosphate decarboxylase by eriochrome compounds DA Skaff, HM Miziorko, WJ McWhorter, BV Geisbrecht ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014 | | 2014 |
| Identification of H. volcanii Phosphomevalonate Decarboxylase and Isopentenyl Phosphate Kinase as Catalysts of the Terminal Enzymatic Reactions in an Archaeal Alternate … H Miziorko, J VanNice, D Skaff, A Keightley, J Addo, G Wyckoff The FASEB Journal 28 (1 Supplement), LB139, 2014 | | 2014 |
| Hymeglusin inhibition of bacterial hydroxymethylglutaryl-CoA synthase (mvaS) HM Miziorko, DA Skaff, KX Ramyar, WJ McWhorter, BV Geisbrecht The FASEB Journal 26 (1_MeetingAbstracts), 964.3, 2012 | | 2012 |
| . MECHANISM OF ATP-DEPENDENT RELEASE OF WILD-TYPE AND MUTANT HUMAN BRAIN HEXOKINASES FROM MITOCHONDRIA N Mehyar, M Watanabe, L Shen, AD Skaff, RB Honzatko Human brain hexokinase: Determinants of mitochondrial binding and mechanism …, 2011 | | 2011 |
| Inhibition of HMG-CoA synthase by drug-like compounds DA Skaff, HM Miziorko ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 238, 682-682, 2009 | | 2009 |
| Release of Human Brain Hexokinase from the Mitochondrial Membrane DA Skaff Iowa State University, 2006 | | 2006 |
