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Thomas G. Scott
Thomas G. Scott
Verified email at virginia.edu
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Cited by
Year
The dTAG system for immediate and target-specific protein degradation
B Nabet, JM Roberts, DL Buckley, J Paulk, S Dastjerdi, A Yang, ...
Nature chemical biology 14 (5), 431-441, 2018
7182018
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment
GE Winter, A Mayer, DL Buckley, MA Erb, JE Roderick, S Vittori, JM Reyes, ...
Molecular cell 67 (1), 5-18. e19, 2017
3912017
Transcription control by the ENL YEATS domain in acute leukaemia
MA Erb, TG Scott, BE Li, H Xie, J Paulk, HS Seo, A Souza, JM Roberts, ...
Nature 543 (7644), 270-274, 2017
2972017
Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands
LN Gechijian, DL Buckley, MA Lawlor, JM Reyes, J Paulk, CJ Ott, ...
Nature chemical biology 14 (4), 405-412, 2018
2132018
Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma
R Zeid, MA Lawlor, E Poon, JM Reyes, M Fulciniti, MA Lopez, TG Scott, ...
Nature genetics 50 (4), 515-523, 2018
1942018
Design and characterization of bivalent BET inhibitors
M Tanaka, JM Roberts, HS Seo, A Souza, J Paulk, TG Scott, SL DeAngelo, ...
Nature chemical biology 12 (12), 1089-1096, 2016
1392016
BET bromodomain inhibitors with one-step synthesis discovered from virtual screen
AM Ayoub, LML Hawk, RJ Herzig, J Jiang, AJ Wisniewski, CT Gee, ...
Journal of medicinal chemistry 60 (12), 4805-4817, 2017
482017
Pojamide: An HDAC3-selective ferrocene analogue with remarkably enhanced redox-triggered ferrocenium activity in cells
CA Ocasio, S Sansook, R Jones, JM Roberts, TG Scott, N Tsoureas, ...
Organometallics 36 (17), 3276-3283, 2017
322017
DNA concentration-dependent dissociation of EcoRI: direct transfer or reaction during hopping
NY Sidorova, T Scott, DC Rau
Biophysical journal 104 (6), 1296-1303, 2013
292013
Enhancer domains in gastrointestinal stromal tumor regulate KIT expression and are targetable by BET bromodomain inhibition
ML Hemming, MA Lawlor, JL Andersen, T Hagan, O Chipashvili, TG Scott, ...
Cancer research 79 (5), 994-1009, 2019
222019
Development of an AchillesTAG degradation system and its application to control CAR-T activity
GK Veits, CS Henderson, A Vogelaar, SJ Eron, L Lee, A Hart, RW Deibler, ...
Current Research in Chemical Biology 1, 100010, 2021
92021
ARF‐AID: A Rapidly Inducible Protein Degradation System that Preserves Basal Endogenous Protein Levels
KM Sathyan, TG Scott, MJ Guertin
Current protocols in molecular biology 132 (1), e124, 2020
72020
Processing and evaluating the quality of genome-wide nascent transcription profiling libraries
TG Scott, AL Martins, MJ Guertin
Biorxiv, 2022.12. 14.520463, 2022
42022
The androgen receptor does not directly regulate the transcription of DNA damage response genes
S Hasterok, TG Scott, DG Roller, A Spencer, AB Dutta, KM Sathyan, ...
Molecular Cancer Research 21 (12), 1329-1341, 2023
12023
TRPS1 modulates chromatin accessibility to regulate estrogen receptor (ER) binding and ER target gene expression in luminal breast cancer cells
TG Scott, KM Sathyan, D Gioeli, MJ Guertin
bioRxiv, 2023
12023
TRPS1 modulates chromatin accessibility to regulate estrogen receptor alpha (ER) binding and ER target gene expression in luminal breast cancer cells
TG Scott, KM Sathyan, D Gioeli, MJ Guertin
PLoS genetics 20 (2), e1011159, 2024
2024
SAT634 The Androgen Receptor Does Not Directly Regulate The Transcription Of DNA Damage Response Genes
S Hasterok, TG Scott, DG Roller, A Spencer, AB Dutta, KM Sathyan, ...
Journal of the Endocrine Society 7 (Supplement_1), bvad114. 2204, 2023
2023
Drugit: Crowd-sourcing molecular design of non-peptidic VHL binders
T Scott, CAP Smethurst, Y Westermaier, M Mayer, P Greb, R Kousek, ...
2023
Basic Protocol 3: Testing auxin-mediated degradation of the AID-tagged protein
KM Sathyan, TG Scott, MJ Guertin
2020
Basic Protocol 1: Generation of eGFP-ARF-P2A-TIR1 or ARF-HA-P2A-TIR1 progenitor cells
KM Sathyan, TG Scott, MJ Guertin
2020
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