The dTAG system for immediate and target-specific protein degradation B Nabet, JM Roberts, DL Buckley, J Paulk, S Dastjerdi, A Yang, ... Nature chemical biology 14 (5), 431-441, 2018 | 718 | 2018 |
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment GE Winter, A Mayer, DL Buckley, MA Erb, JE Roderick, S Vittori, JM Reyes, ... Molecular cell 67 (1), 5-18. e19, 2017 | 391 | 2017 |
Transcription control by the ENL YEATS domain in acute leukaemia MA Erb, TG Scott, BE Li, H Xie, J Paulk, HS Seo, A Souza, JM Roberts, ... Nature 543 (7644), 270-274, 2017 | 297 | 2017 |
Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands LN Gechijian, DL Buckley, MA Lawlor, JM Reyes, J Paulk, CJ Ott, ... Nature chemical biology 14 (4), 405-412, 2018 | 213 | 2018 |
Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma R Zeid, MA Lawlor, E Poon, JM Reyes, M Fulciniti, MA Lopez, TG Scott, ... Nature genetics 50 (4), 515-523, 2018 | 194 | 2018 |
Design and characterization of bivalent BET inhibitors M Tanaka, JM Roberts, HS Seo, A Souza, J Paulk, TG Scott, SL DeAngelo, ... Nature chemical biology 12 (12), 1089-1096, 2016 | 139 | 2016 |
BET bromodomain inhibitors with one-step synthesis discovered from virtual screen AM Ayoub, LML Hawk, RJ Herzig, J Jiang, AJ Wisniewski, CT Gee, ... Journal of medicinal chemistry 60 (12), 4805-4817, 2017 | 48 | 2017 |
Pojamide: An HDAC3-selective ferrocene analogue with remarkably enhanced redox-triggered ferrocenium activity in cells CA Ocasio, S Sansook, R Jones, JM Roberts, TG Scott, N Tsoureas, ... Organometallics 36 (17), 3276-3283, 2017 | 32 | 2017 |
DNA concentration-dependent dissociation of EcoRI: direct transfer or reaction during hopping NY Sidorova, T Scott, DC Rau Biophysical journal 104 (6), 1296-1303, 2013 | 29 | 2013 |
Enhancer domains in gastrointestinal stromal tumor regulate KIT expression and are targetable by BET bromodomain inhibition ML Hemming, MA Lawlor, JL Andersen, T Hagan, O Chipashvili, TG Scott, ... Cancer research 79 (5), 994-1009, 2019 | 22 | 2019 |
Development of an AchillesTAG degradation system and its application to control CAR-T activity GK Veits, CS Henderson, A Vogelaar, SJ Eron, L Lee, A Hart, RW Deibler, ... Current Research in Chemical Biology 1, 100010, 2021 | 9 | 2021 |
ARF‐AID: A Rapidly Inducible Protein Degradation System that Preserves Basal Endogenous Protein Levels KM Sathyan, TG Scott, MJ Guertin Current protocols in molecular biology 132 (1), e124, 2020 | 7 | 2020 |
Processing and evaluating the quality of genome-wide nascent transcription profiling libraries TG Scott, AL Martins, MJ Guertin Biorxiv, 2022.12. 14.520463, 2022 | 4 | 2022 |
The androgen receptor does not directly regulate the transcription of DNA damage response genes S Hasterok, TG Scott, DG Roller, A Spencer, AB Dutta, KM Sathyan, ... Molecular Cancer Research 21 (12), 1329-1341, 2023 | 1 | 2023 |
TRPS1 modulates chromatin accessibility to regulate estrogen receptor (ER) binding and ER target gene expression in luminal breast cancer cells TG Scott, KM Sathyan, D Gioeli, MJ Guertin bioRxiv, 2023 | 1 | 2023 |
TRPS1 modulates chromatin accessibility to regulate estrogen receptor alpha (ER) binding and ER target gene expression in luminal breast cancer cells TG Scott, KM Sathyan, D Gioeli, MJ Guertin PLoS genetics 20 (2), e1011159, 2024 | | 2024 |
SAT634 The Androgen Receptor Does Not Directly Regulate The Transcription Of DNA Damage Response Genes S Hasterok, TG Scott, DG Roller, A Spencer, AB Dutta, KM Sathyan, ... Journal of the Endocrine Society 7 (Supplement_1), bvad114. 2204, 2023 | | 2023 |
Drugit: Crowd-sourcing molecular design of non-peptidic VHL binders T Scott, CAP Smethurst, Y Westermaier, M Mayer, P Greb, R Kousek, ... | | 2023 |
Basic Protocol 3: Testing auxin-mediated degradation of the AID-tagged protein KM Sathyan, TG Scott, MJ Guertin | | 2020 |
Basic Protocol 1: Generation of eGFP-ARF-P2A-TIR1 or ARF-HA-P2A-TIR1 progenitor cells KM Sathyan, TG Scott, MJ Guertin | | 2020 |