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Prof. Dr. med. Christoph Kuppe, Ph.D.
Prof. Dr. med. Christoph Kuppe, Ph.D.
Emmy Noether Research Group Leader, RWTH Aachen University, Nephrology
Verifierad e-postadress på ukaachen.de
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Decoding myofibroblast origins in human kidney fibrosis
C Kuppe, MM Ibrahim, J Kranz, X Zhang, S Ziegler, J Perales-Patón, ...
Nature 589 (7841), 281-286, 2021
4222021
Adventitial MSC-like cells are progenitors of vascular smooth muscle cells and drive vascular calcification in chronic kidney disease
R Kramann, C Goettsch, J Wongboonsin, H Iwata, RK Schneider, ...
Cell stem cell 19 (5), 628-642, 2016
3042016
Parietal epithelial cells participate in the formation of sclerotic lesions in focal segmental glomerulosclerosis
B Smeets, C Kuppe, EM Sicking, A Fuss, P Jirak, TH Van Kuppevelt, ...
Journal of the American Society of Nephrology 22 (7), 1262-1274, 2011
2452011
Spatial multi-omic map of human myocardial infarction
C Kuppe, RO Ramirez Flores, Z Li, S Hayat, RT Levinson, X Liao, ...
Nature 608 (7924), 766-777, 2022
2212022
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ...
Cell Stem Cell 29 (2), 217-231. e8, 2022
1722022
Chemokine Cxcl9 attenuates liver fibrosis‐associated angiogenesis in mice
H Sahin, E Borkham‐Kamphorst, C Kuppe, MM Zaldivar, C Grouls, ...
Hepatology 55 (5), 1610-1619, 2012
1492012
The regenerative potential of parietal epithelial cells in adult mice
K Berger, K Schulte, P Boor, C Kuppe, TH van Kuppevelt, J Floege, ...
Journal of the American Society of Nephrology 25 (4), 693-705, 2014
1162014
Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses
A Dugourd, C Kuppe, M Sciacovelli, E Gjerga, A Gabor, KB Emdal, ...
Molecular Systems Biology 17 (1), e9730, 2021
1062021
Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis
NB Leimkühler, HFE Gleitz, L Ronghui, IAM Snoeren, SNR Fuchs, ...
Cell Stem Cell 28 (4), 637-652. e8, 2021
1002021
Electrical forces determine glomerular permeability
R Hausmann, C Kuppe, H Egger, F Schweda, V Knecht, M Elger, ...
Journal of the American Society of Nephrology 21 (12), 2053-2058, 2010
882010
Only hyperuricemia with crystalluria, but not asymptomatic hyperuricemia, drives progression of chronic kidney disease
M Sellmayr, MRH Petzsche, Q Ma, N Krüger, H Liapis, A Brink, B Lenz, ...
Journal of the American Society of Nephrology 31 (12), 2773-2792, 2020
842020
mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans
VG Puelles, JW Van Der Wolde, N Wanner, MW Scheppach, ...
JCI insight 4 (18), 2019
782019
Common histological patterns in glomerular epithelial cells in secondary focal segmental glomerulosclerosis
C Kuppe, HJ Gröne, T Ostendorf, TH Van Kuppevelt, P Boor, J Floege, ...
Kidney international 88 (5), 990-998, 2015
692015
Primary cultures of glomerular parietal epithelial cells or podocytes with proven origin
N Kabgani, T Grigoleit, K Schulte, A Sechi, S Sauer-Lehnen, C Tag, ...
PloS one 7 (4), e34907, 2012
652012
Investigations of glucocorticoid action in GN
C Kuppe, C Van Roeyen, K Leuchtle, N Kabgani, M Vogt, ...
Journal of the American Society of Nephrology 28 (5), 1408-1420, 2017
622017
Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen
Z Li, C Kuppe, S Ziegler, M Cheng, N Kabgani, S Menzel, M Zenke, ...
Nature communications 12 (1), 6386, 2021
612021
Novel parietal epithelial cell subpopulations contribute to focal segmental glomerulosclerosis and glomerular tip lesions
C Kuppe, K Leuchtle, A Wagner, N Kabgani, T Saritas, VG Puelles, ...
Kidney international 96 (1), 80-93, 2019
582019
Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single-cell sequencing
K van Kuijk, C Kuppe, C Betsholtz, M Vanlandewijck, R Kramann, ...
Cardiovascular Research 115 (12), 1705-1715, 2019
442019
Role of mesenchymal stem cells in kidney injury and fibrosis
C Kuppe, R Kramann
Current Opinion in Nephrology and Hypertension 25 (4), 372-377, 2016
442016
Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis
VG Puelles, D Fleck, L Ortz, S Papadouri, T Strieder, AMC Böhner, ...
Kidney international 96 (2), 505-516, 2019
432019
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Artiklar 1–20