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Julia Keith
Julia Keith
Assistant Professor of Neuropathology, University of Toronto
Verifierad e-postadress på utoronto.ca
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TIA1 mutations in amyotrophic lateral sclerosis and frontotemporal dementia promote phase separation and alter stress granule dynamics
IR Mackenzie, AM Nicholson, M Sarkar, J Messing, MD Purice, C Pottier, ...
Neuron 95 (4), 808-816. e9, 2017
5592017
Hypermethylation of the CpG island near the G4C2 repeat in ALS with a C9orf72 expansion
Z Xi, L Zinman, D Moreno, J Schymick, Y Liang, C Sato, Y Zheng, M Ghani, ...
The American Journal of Human Genetics 92 (6), 981-989, 2013
3322013
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture
R Chia, MS Sabir, S Bandres-Ciga, S Saez-Atienzar, RH Reynolds, ...
Nature genetics 53 (3), 294-303, 2021
2142021
RNA targets of TDP-43 identified by UV-CLIP are deregulated in ALS
S Xiao, T Sanelli, S Dib, D Sheps, J Findlater, J Bilbao, J Keith, L Zinman, ...
Molecular and Cellular Neuroscience 47 (3), 167-180, 2011
1992011
Isoform‐specific antibodies reveal distinct subcellular localizations of C 9orf72 in amyotrophic lateral sclerosis
S Xiao, L MacNair, P McGoldrick, PM McKeever, JR McLean, M Zhang, ...
Annals of neurology 78 (4), 568-583, 2015
1802015
Prevalence of amyloid‐β pathology in distinct variants of primary progressive aphasia
D Bergeron, ML Gorno‐Tempini, GD Rabinovici, MA Santos‐Santos, ...
Annals of neurology 84 (5), 729-740, 2018
1792018
The C9orf72 repeat expansion itself is methylated in ALS and FTLD patients
Z Xi, M Zhang, AC Bruni, RG Maletta, R Colao, P Fratta, JM Polke, ...
Acta neuropathologica 129 (5), 715-727, 2015
1582015
A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy
M Chitiprolu, C Jagow, V Tremblay, E Bondy-Chorney, G Paris, A Savard, ...
Nature communications 9 (1), 2794, 2018
1532018
Collagenosis of the deep medullary veins: an underrecognized pathologic correlate of white matter hyperintensities and periventricular infarction?
J Keith, FQ Gao, R Noor, A Kiss, G Balasubramaniam, K Au, E Rogaeva, ...
Journal of Neuropatholgy & Experimental Neurology 76 (4), 299-312, 2017
1382017
BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency
B Afzali, J Grönholm, J Vandrovcova, C O'Brien, HW Sun, I Vanderleyden, ...
Nature immunology 18 (7), 813-823, 2017
1372017
Radiation-induced vertebral compression fracture following spine stereotactic radiosurgery: clinicopathological correlation: report of 2 cases
A Al-Omair, R Smith, TR Kiehl, L Lao, E Yu, EM Massicotte, J Keith, ...
Journal of Neurosurgery: Spine 18 (5), 430-435, 2013
962013
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in …
C Pottier, Y Ren, RB Perkerson, M Baker, GD Jenkins, M van Blitterswijk, ...
Acta neuropathologica 137, 879-899, 2019
952019
Mutation analysis of CHCHD10 in different neurodegenerative diseases
M Zhang, Z Xi, L Zinman, AC Bruni, RG Maletta, SAM Curcio, I Rainero, ...
Brain 138 (9), e380-e380, 2015
952015
Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death
S Xiao, T Sanelli, H Chiang, Y Sun, A Chakrabartty, J Keith, E Rogaeva, ...
Acta neuropathologica 130, 49-61, 2015
922015
MR-guided focused ultrasound liquid biopsy enriches circulating biomarkers in patients with brain tumors
Y Meng, CB Pople, S Suppiah, M Llinas, Y Huang, A Sahgal, J Perry, ...
Neuro-oncology 23 (10), 1789-1797, 2021
802021
Immune dysregulation in patients with PTEN hamartoma tumor syndrome: analysis of FOXP3 regulatory T cells
HH Chen, N Händel, J Ngeow, J Muller, M Hühn, HT Yang, M Heindl, ...
Journal of Allergy and Clinical Immunology 139 (2), 607-620. e15, 2017
782017
Jump from pre-mutation to pathologic expansion in C9orf72
Z Xi, M van Blitterswijk, M Zhang, P McGoldrick, JR McLean, Y Yunusova, ...
The American Journal of Human Genetics 96 (6), 962-970, 2015
762015
Differentiating radiation necrosis from tumor progression in brain metastases treated with stereotactic radiotherapy: utility of intravoxel incoherent motion perfusion MRI and …
JS Detsky, J Keith, J Conklin, S Symons, S Myrehaug, A Sahgal, CC Heyn, ...
Journal of neuro-oncology 134, 433-441, 2017
722017
The neuropathological signature of bulbar-onset ALS: a systematic review
S Shellikeri, V Karthikeyan, R Martino, SE Black, L Zinman, J Keith, ...
Neuroscience & Biobehavioral Reviews 75, 378-392, 2017
702017
Pathogenic huntingtin repeat expansions in patients with frontotemporal dementia and amyotrophic lateral sclerosis
R Dewan, R Chia, J Ding, RA Hickman, TD Stein, Y Abramzon, S Ahmed, ...
Neuron 109 (3), 448-460. e4, 2021
672021
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Artiklar 1–20