| Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome K Nakahira, JA Haspel, VAK Rathinam, SJ Lee, T Dolinay, HC Lam, ... Nature immunology 12 (3), 222-230, 2011 | 2920 | 2011 |
| Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock R Yang, T Harada, KP Mollen, JM Prince, RM Levy, JA Englert, ... Molecular medicine 12, 105-114, 2006 | 271 | 2006 |
| Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients National Heart, Lung, and Blood Institute PETAL Clinical Trials Network New England Journal of Medicine 381 (26), 2529-2540, 2019 | 179 | 2019 |
| Circadian rhythm reprogramming during lung inflammation JA Haspel, S Chettimada, RS Shaik, JH Chu, BA Raby, M Cernadas, ... Nature communications 5 (1), 4753, 2014 | 179 | 2014 |
| Ethyl pyruvate inhibits nuclear factor-κB-dependent signaling by directly targeting p65 Y Han, JA Englert, R Yang, RL Delude, MP Fink Journal of Pharmacology and Experimental Therapeutics 312 (3), 1097-1105, 2005 | 174 | 2005 |
| Integrating molecular pathogenesis and clinical translation in sepsis-induced acute respiratory distress syndrome JA Englert, C Bobba, RM Baron JCI insight 4 (2), 2019 | 155 | 2019 |
| Characterization of macroautophagic flux in vivo using a leupeptin-based assay J Haspel, RS Shaik, E Ifedigbo, K Nakahira, T Dolinay, JA Englert, ... Autophagy 7 (6), 629-642, 2011 | 154 | 2011 |
| Update on the features and measurements of experimental acute lung injury in animals: an official American Thoracic Society workshop report HS Kulkarni, JS Lee, JA Bastarache, WM Kuebler, GP Downey, ... American journal of respiratory cell and molecular biology 66 (2), e1-e14, 2022 | 106 | 2022 |
| Bile modulates intestinal epithelial barrier function via an extracellular signal related kinase 1/2 dependent mechanism R Yang, T Harada, J Li, T Uchiyama, Y Han, JA Englert, MP Fink Intensive care medicine 31, 709-717, 2005 | 106 | 2005 |
| A phase I trial of low-dose inhaled carbon monoxide in sepsis-induced ARDS LE Fredenburgh, MA Perrella, D Barragan-Bradford, DR Hess, E Peters, ... JCI insight 3 (23), 2018 | 90 | 2018 |
| Early neuromuscular blockade in the acute respiratory distress syndrome National Heart, Lung, and Blood Institute PETAL Clinical Trials Network New England Journal of Medicine 380 (21), 1997-2008, 2019 | 85 | 2019 |
| Metabolism, metabolomics, and nutritional support of patients with sepsis JA Englert, AJ Rogers Clinics in chest medicine 37 (2), 321-331, 2016 | 85 | 2016 |
| Autophagy proteins regulate innate immune response by inhibiting NALP3 inflammasome-mediated mitochondrial DNA release K Nakahira, JA Haspel, VAK Rathinam, SJ Lee, T Dolinay, HC Lam, ... Nature immunology 12 (3), 222, 2011 | 78 | 2011 |
| Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis LE Fredenburgh, MM Suárez Velandia, J Ma, T Olszak, M Cernadas, ... The Journal of Immunology 187 (10), 5255-5267, 2011 | 73 | 2011 |
| Isoflurane ameliorates acute lung injury by preserving epithelial tight junction integrity JA Englert, AA Macias, D Amador-Munoz, M Pinilla Vera, C Isabelle, ... Anesthesiology 123 (2), 377-388, 2015 | 69 | 2015 |
| Using a novel microfabricated model of the alveolar-capillary barrier to investigate the effect of matrix structure on atelectrauma N Higuita-Castro, MT Nelson, V Shukla, PA Agudelo-Garcia, W Zhang, ... Scientific reports 7 (1), 11623, 2017 | 68 | 2017 |
| Zinc deficiency primes the lung for ventilator-induced injury F Boudreault, M Pinilla-Vera, JA Englert, AT Kho, C Isabelle, ... JCI insight 2 (11), 2017 | 66 | 2017 |
| Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study T Pham, L Heunks, G Bellani, F Madotto, I Aragao, G Beduneau, ... The Lancet Respiratory Medicine 11 (5), 465-476, 2023 | 58 | 2023 |
| The phase 2 enzyme inducers ethacrynic acid, DL-sulforaphane, and oltipraz inhibit lipopolysaccharide-induced high-mobility group box 1 secretion by RAW 264.7 cells ME Killeen, JA Englert, DB Stolz, M Song, Y Han, RL Delude, JA Kellum, ... Journal of Pharmacology and Experimental Therapeutics 316 (3), 1070-1079, 2006 | 58 | 2006 |
| Ventilator-induced lung injury increases expression of endothelial inflammatory mediators in the kidney M Hepokoski, JA Englert, RM Baron, LE Crotty-Alexander, MM Fuster, ... American Journal of Physiology-Renal Physiology 312 (4), F654-F660, 2017 | 51 | 2017 |
