Pedro P. Rocha
Pedro P. Rocha
Tenure-track Investigator NIH / NICHD
Verifierad e-postadress på nih.gov - Startsida
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CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation
V Narendra, PP Rocha, D An, R Raviram, JA Skok, EO Mazzoni, ...
Science 347 (6225), 1017-1021, 2015
3592015
Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling
PP Rocha, M Scholze, W Bleiß, H Schrewe
Development 137 (16), 2723-2731, 2010
1302010
Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms
J Mullenders, B Aranda-Orgilles, P Lhoumaud, M Keller, J Pae, K Wang, ...
Journal of Experimental Medicine 212 (11), 1833-1850, 2015
922015
Capturing the onset of PRC2-mediated repressive domain formation
O Oksuz, V Narendra, CH Lee, N Descostes, G LeRoy, R Raviram, ...
Molecular cell 70 (6), 1149-1162. e5, 2018
752018
CRISPR-dCas9 and sgRNA scaffolds enable dual-colour live imaging of satellite sequences and repeat-enriched individual loci
Y Fu, PP Rocha, VM Luo, R Raviram, Y Deng, EO Mazzoni, JA Skok
Nature communications 7 (1), 1-8, 2016
692016
MED12 regulates HSC-specific enhancers independently of mediator kinase activity to control hematopoiesis
B Aranda-Orgilles, R Saldaña-Meyer, E Wang, E Trompouki, A Fassl, ...
Cell Stem Cell 19 (6), 784-799, 2016
572016
Close proximity to Igh is a contributing factor to AID-mediated translocations
PP Rocha, M Micsinai, JHR Kim, SL Hewitt, PP Souza, T Trimarchi, ...
Molecular cell 47 (6), 873-885, 2012
552012
4C-ker: A Method to Reproducibly Identify Genome-Wide Interactions Captured by 4C-Seq Experiments
JAS Ramya Raviram, Pedro P. Rocha, Christian L. Müller, Emily R. Miraldi ...
Plos Computational Biology, 2016
512016
Lack of functional and expression homology between human and mouse aldo-keto reductase 1C enzymes: implications for modelling human cancers
P Veliça, NJ Davies, PP Rocha, H Schrewe, JP Ride, CM Bunce
Molecular cancer 8 (1), 121, 2009
462009
Low-grade astrocytoma mutations in IDH1, P53, and ATRX cooperate to block differentiation of human neural stem cells via repression of SOX2
AS Modrek, D Golub, T Khan, D Bready, J Prado, C Bowman, J Deng, ...
Cell reports 21 (5), 1267-1280, 2017
342017
Breaking TADs: insights into hierarchical genome organization
PP Rocha, R Raviram, R Bonneau, JA Skok
Epigenomics 7 (4), 523-526, 2015
312015
Identification of multi-loci hubs from 4C-seq demonstrates the functional importance of simultaneous interactions
T Jiang, R Raviram, V Snetkova, PP Rocha, C Proudhon, S Badri, ...
Nucleic acids research 44 (18), 8714-8725, 2016
272016
Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination
AS Thomas-Claudepierre, I Robert, PP Rocha, R Raviram, E Schiavo, ...
Journal of Experimental Medicine 213 (3), 303-312, 2016
262016
A damage-independent role for 53BP1 that impacts break order and Igh architecture during class switch recombination
PP Rocha, R Raviram, Y Fu, JH Kim, VM Luo, A Aljoufi, E Swanzey, ...
Cell reports 16 (1), 48-55, 2016
212016
Wolf-Hirschhorn syndrome candidate 1 is necessary for correct hematopoietic and B cell development
E Campos-Sanchez, N Deleyto-Seldas, V Dominguez, ...
Cell reports 19 (8), 1586-1601, 2017
152017
Interpreting 4C-Seq data: how far can we go?
R Raviram, PP Rocha, R Bonneau, JA Skok
Epigenomics 6 (5), 455-457, 2014
122014
The origin of recurrent translocations in recombining lymphocytes: a balance between break frequency and nuclear proximity
PP Rocha, JA Skok
Current opinion in cell biology 25 (3), 365-371, 2013
112013
Mosaic expression of Med12 in female mice leads to exencephaly, spina bifida, and craniorachischisis
PP Rocha, W Bleiss, H Schrewe
Birth Defects Research Part A: Clinical and Molecular Teratology 88 (8), 626-632, 2010
112010
Analysis of 3D genomic interactions identifies candidate host genes that transposable elements potentially regulate
R Raviram, PP Rocha, VM Luo, E Swanzey, ER Miraldi, EB Chuong, ...
Genome biology 19 (1), 1-19, 2018
102018
Finding the right partner in a 3D genome
PP Rocha, J Chaumeil, JA Skok
Science 342 (6164), 1333-1334, 2013
82013
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Artiklar 1–20