Ravi R. Iyer, Ph.D.
Ravi R. Iyer, Ph.D.
CHDI Foundation
Verifierad e-postadress på chdifoundation.org
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DNA mismatch repair: functions and mechanisms
RR Iyer, A Pluciennik, V Burdett, PL Modrich
Chemical reviews 106 (2), 302-323, 2006
9882006
Structure of the human MutSα DNA lesion recognition complex
JJ Warren, TJ Pohlhaus, A Changela, RR Iyer, PL Modrich, LS Beese
Molecular cell 26 (4), 579-592, 2007
3272007
A defined human system that supports bidirectional mismatch-provoked excision
L Dzantiev, N Constantin, J Genschel, RR Iyer, PM Burgers, P Modrich
Molecular cell 15 (1), 31-41, 2004
2782004
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
A Pluciennik, L Dzantiev, RR Iyer, N Constantin, FA Kadyrov, P Modrich
Proceedings of the National Academy of Sciences 107 (37), 16066-16071, 2010
2452010
Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family
J Orans, EA McSweeney, RR Iyer, MA Hast, HW Hellinga, P Modrich, ...
Cell 145 (2), 212-223, 2011
1502011
Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
J Zhao, A Jain, RR Iyer, PL Modrich, KM Vasquez
Nucleic acids research 37 (13), 4420-4429, 2009
1022009
DNA triplet repeat expansion and mismatch repair
RR Iyer, A Pluciennik, M Napierala, RD Wells
Annual review of biochemistry 84, 199-226, 2015
982015
GGA· TCC-interrupted triplets in long GAA· TTC repeats inhibit the formation of triplex and sticky DNA structures, alleviate transcription inhibition, and reduce genetic …
N Sakamoto, JE Larson, RR Iyer, L Montermini, M Pandolfo, RD Wells
Journal of Biological Chemistry 276 (29), 27178-27187, 2001
902001
Sticky DNA, a long GAA· GAA· TTC triplex that is formed intramolecularly, in the sequence of intron 1 of the frataxin gene
AA Vetcher, M Napierala, RR Iyer, PD Chastain, JD Griffith, RD Wells
Journal of Biological Chemistry 277 (42), 39217-39227, 2002
732002
DNA polymerase III proofreading mutants enhance the expansion and deletion of triplet repeat sequences in Escherichia coli
RR Iyer, A Pluciennik, WA Rosche, RR Sinden, RD Wells
Journal of Biological Chemistry 275 (3), 2174-2184, 2000
692000
Expansion and Deletion of Triplet Repeat Sequences inEscherichia coli Occur on the Leading Strand of DNA Replication
RR Iyer, RD Wells
Journal of Biological Chemistry 274 (6), 3865-3877, 1999
681999
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
A Pluciennik, V Burdett, C Baitinger, RR Iyer, K Shi, P Modrich
Proceedings of the National Academy of Sciences 110 (30), 12277-12282, 2013
592013
Long CTG tracts from the myotonic dystrophy gene induce deletions and rearrangements during recombination at the APRT locus in CHO cells
JL Meservy, RG Sargent, RR Iyer, F Chan, GJ McKenzie, RD Wells, ...
Molecular and cellular biology 23 (9), 3152-3162, 2003
572003
The MutSα-proliferating cell nuclear antigen interaction in human DNA mismatch repair
RR Iyer, TJ Pohlhaus, S Chen, GL Hura, L Dzantiev, LS Beese, P Modrich
Journal of Biological Chemistry 283 (19), 13310-13319, 2008
532008
MutLα and proliferating cell nuclear antigen share binding sites on MutSβ
RR Iyer, A Pluciennik, J Genschel, MS Tsai, LS Beese, P Modrich
Journal of Biological Chemistry 285 (15), 11730-11739, 2010
502010
Coupling of human DNA excision repair and the DNA damage checkpoint in a defined in vitro system
LA Lindsey-Boltz, MG Kemp, JT Reardon, V DeRocco, RR Iyer, P Modrich, ...
Journal of Biological Chemistry 289 (8), 5074-5082, 2014
492014
Long CTG· CAG repeats from myotonic dystrophy are preferred sites for intermolecular recombination
A Pluciennik, RR Iyer, M Napierala, JE Larson, M Filutowicz, RD Wells
Journal of Biological Chemistry 277 (37), 34074-34086, 2002
472002
Structure of the murine Mac-2 gene. Splice variants encode proteins lacking functional signal peptides
IM Rosenberg, R Iyer, B Cherayil, C Chiodino, S Pillai
Journal of Biological Chemistry 268 (17), 12393-12400, 1993
411993
Tandem duplication: a novel type of triplet repeat instability
A Pluciennik, RR Iyer, P Parniewski, RD Wells
Journal of Biological Chemistry 275 (37), 28386-28397, 2000
302000
Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLα activation and function in mismatch repair
J Genschel, LY Kadyrova, RR Iyer, BK Dahal, FA Kadyrov, P Modrich
Proceedings of the National Academy of Sciences 114 (19), 4930-4935, 2017
262017
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