| DNA mismatch repair: functions and mechanisms RR Iyer, A Pluciennik, V Burdett, PL Modrich Chemical reviews 106 (2), 302-323, 2006 | 1151 | 2006 |
| Structure of the human MutSα DNA lesion recognition complex JJ Warren, TJ Pohlhaus, A Changela, RR Iyer, PL Modrich, LS Beese Molecular cell 26 (4), 579-592, 2007 | 391 | 2007 |
| PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair A Pluciennik, L Dzantiev, RR Iyer, N Constantin, FA Kadyrov, P Modrich Proceedings of the National Academy of Sciences 107 (37), 16066-16071, 2010 | 317 | 2010 |
| A defined human system that supports bidirectional mismatch-provoked excision L Dzantiev, N Constantin, J Genschel, RR Iyer, PM Burgers, P Modrich Molecular cell 15 (1), 31-41, 2004 | 310 | 2004 |
| Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family J Orans, EA McSweeney, RR Iyer, MA Hast, HW Hellinga, P Modrich, ... Cell 145 (2), 212-223, 2011 | 190 | 2011 |
| DNA triplet repeat expansion and mismatch repair RR Iyer, A Pluciennik, M Napierala, RD Wells Annual review of biochemistry 84, 199-226, 2015 | 129 | 2015 |
| Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks J Zhao, A Jain, RR Iyer, PL Modrich, KM Vasquez Nucleic acids research 37 (13), 4420-4429, 2009 | 116 | 2009 |
| GGA· TCC-interrupted triplets in long GAA· TTC repeats inhibit the formation of triplex and sticky DNA structures, alleviate transcription inhibition, and reduce genetic … N Sakamoto, JE Larson, RR Iyer, L Montermini, M Pandolfo, RD Wells Journal of Biological Chemistry 276 (29), 27178-27187, 2001 | 100 | 2001 |
| Sticky DNA, a long GAA· GAA· TTC triplex that is formed intramolecularly, in the sequence of intron 1 of the frataxin gene AA Vetcher, M Napierala, RR Iyer, PD Chastain, JD Griffith, RD Wells Journal of Biological Chemistry 277 (42), 39217-39227, 2002 | 85 | 2002 |
| Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation A Pluciennik, V Burdett, C Baitinger, RR Iyer, K Shi, P Modrich Proceedings of the National Academy of Sciences 110 (30), 12277-12282, 2013 | 78 | 2013 |
| DNA polymerase III proofreading mutants enhance the expansion and deletion of triplet repeat sequences in Escherichia coli RR Iyer, A Pluciennik, WA Rosche, RR Sinden, RD Wells Journal of Biological Chemistry 275 (3), 2174-2184, 2000 | 75 | 2000 |
| Expansion and Deletion of Triplet Repeat Sequences inEscherichia coli Occur on the Leading Strand of DNA Replication RR Iyer, RD Wells Journal of Biological Chemistry 274 (6), 3865-3877, 1999 | 72 | 1999 |
| The MutSα-Proliferating Cell Nuclear Antigen Interaction in Human DNA Mismatch Repair*♦ RR Iyer, TJ Pohlhaus, S Chen, GL Hura, L Dzantiev, LS Beese, P Modrich Journal of Biological Chemistry 283 (19), 13310-13319, 2008 | 66 | 2008 |
| Coupling of human DNA excision repair and the DNA damage checkpoint in a defined in vitro system LA Lindsey-Boltz, MG Kemp, JT Reardon, V DeRocco, RR Iyer, P Modrich, ... Journal of Biological Chemistry 289 (8), 5074-5082, 2014 | 65 | 2014 |
| MutLα and proliferating cell nuclear antigen share binding sites on MutSβ RR Iyer, A Pluciennik, J Genschel, MS Tsai, LS Beese, P Modrich Journal of biological chemistry 285 (15), 11730-11739, 2010 | 65 | 2010 |
| Long CTG tracts from the myotonic dystrophy gene induce deletions and rearrangements during recombination at the APRT locus in CHO cells JL Meservy, RG Sargent, RR Iyer, F Chan, GJ McKenzie, RD Wells, ... Molecular and Cellular Biology, 2003 | 59 | 2003 |
| DNA mismatch repair and its role in Huntington’s disease RR Iyer, A Pluciennik Journal of Huntington's Disease 10 (1), 75-94, 2021 | 55 | 2021 |
| Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLα activation and function in mismatch repair J Genschel, LY Kadyrova, RR Iyer, BK Dahal, FA Kadyrov, P Modrich Proceedings of the National Academy of Sciences 114 (19), 4930-4935, 2017 | 53 | 2017 |
| Long CTG· CAG repeats from myotonic dystrophy are preferred sites for intermolecular recombination A Pluciennik, RR Iyer, M Napierala, JE Larson, M Filutowicz, RD Wells Journal of Biological Chemistry 277 (37), 34074-34086, 2002 | 51 | 2002 |
| Structure of the murine Mac-2 gene. Splice variants encode proteins lacking functional signal peptides IM Rosenberg, R Iyer, B Cherayil, C Chiodino, S Pillai Journal of Biological Chemistry 268 (17), 12393-12400, 1993 | 42 | 1993 |
Marek NapieralaAssociate Professor, University of Texas Southwestern Medical CenterVerifierad e-postadress på utsouthwestern.edu
