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Christine Luong Yu
Christine Luong Yu
Principal Scientific Researcher, Genentech
Verifierad e-postadress på gene.com
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Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases
JR Somoza, RJ Skene, BA Katz, C Mol, JD Ho, AJ Jennings, C Luong, ...
Structure 12 (7), 1325-1334, 2004
8352004
Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2
C Luong, A Miller, J Barnett, J Chow, C Ramesha, MF Browner
Nature structural biology 3 (11), 927-933, 1996
7801996
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies
K Newton, ML Matsumoto, IE Wertz, DS Kirkpatrick, JR Lill, J Tan, ...
Cell 134 (4), 668-678, 2008
6552008
Effect of outpatient pharmacists' non‐dispensing roles on patient outcomes and prescribing patterns
N Nkansah, O Mostovetsky, C Yu, T Chheng, J Beney, CM Bond, L Bero
Cochrane database of systematic reviews, 2010
4732010
K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody
ML Matsumoto, KE Wickliffe, KC Dong, C Yu, I Bosanac, D Bustos, L Phu, ...
Molecular cell 39 (3), 477-484, 2010
4672010
Specific Btk inhibition suppresses B cell–and myeloid cell–mediated arthritis
JA Di Paolo, T Huang, M Balazs, J Barbosa, KH Barck, BJ Bravo, ...
Nature chemical biology 7 (1), 41-50, 2011
3832011
USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria
CN Cunningham, JM Baughman, L Phu, JS Tea, C Yu, M Coons, ...
Nature cell biology 17 (2), 160-169, 2015
3272015
Crystal structures of MMP-1 and-13 reveal the structural basis for selectivity of collagenase inhibitors
B Lovejoy, AR Welch, S Carr, C Luong, C Broka, R Hendricks, ...
Nature structural biology 6 (3), 217-221, 1999
3121999
Ubiquitin binding to A20 ZnF4 is required for modulation of NF-κB signaling
I Bosanac, IE Wertz, B Pan, C Yu, S Kusam, C Lam, L Phu, Q Phung, ...
Molecular cell 40 (4), 548-557, 2010
2192010
Activation mechanism of oncogenic deletion mutations in BRAF, EGFR, and HER2
SA Foster, DM Whalen, A Özen, MJ Wongchenko, JP Yin, I Yen, ...
Cancer cell 29 (4), 477-493, 2016
2052016
Design of potent selective zinc-mediated serine protease inhibitors
BA Katz, JM Clark, JS Finer-Moore, TE Jenkins, CR Johnson, MJ Ross, ...
Nature 391 (6667), 608-612, 1998
2011998
Development of serine protease inhibitors displaying a multicentered short (< 2.3 Å) hydrogen bond binding mode: Inhibitors of urokinase-type plasminogen activator and factor Xa
E Verner, BA Katz, JR Spencer, D Allen, J Hataye, W Hruzewicz, HC Hui, ...
Journal of medicinal chemistry 44 (17), 2753-2771, 2001
1612001
Battling Btk mutants with noncovalent inhibitors that overcome Cys481 and Thr474 mutations
AR Johnson, PB Kohli, A Katewa, E Gogol, LD Belmont, R Choy, ...
ACS chemical biology 11 (10), 2897-2907, 2016
1402016
Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling
XD Huang, JC McGann, BY Liu, RN Hannoush, JR Lill, V Pham, ...
Science 339 (6126), 1441-1445, 2013
1292013
Engineering and structural characterization of a linear polyubiquitin-specific antibody
ML Matsumoto, KC Dong, C Yu, L Phu, X Gao, RN Hannoush, ...
Journal of molecular biology 418 (3-4), 134-144, 2012
1242012
Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator
BA Katz, R Mackman, C Luong, K Radika, A Martelli, PA Sprengeler, ...
Chemistry & biology 7 (4), 299-312, 2000
1202000
Exploiting subsite S1 of trypsin-like serine proteases for selectivity: potent and selective inhibitors of urokinase-type plasminogen activator
RL Mackman, BA Katz, JG Breitenbucher, HC Hui, E Verner, C Luong, ...
Journal of medicinal chemistry 44 (23), 3856-3871, 2001
1132001
The structure of the extracellular region of human hepsin reveals a serine protease domain and a novel scavenger receptor cysteine-rich (SRCR) domain
JR Somoza, JD Ho, C Luong, M Ghate, PA Sprengeler, K Mortara, ...
Structure 11 (9), 1123-1131, 2003
1052003
Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets
BA Katz, PA Sprengeler, C Luong, E Verner, K Elrod, M Kirtley, J Janc, ...
Chemistry & biology 8 (11), 1107-1121, 2001
942001
A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site
BA Katz, K Elrod, C Luong, MJ Rice, RL Mackman, PA Sprengeler, ...
Journal of molecular biology 307 (5), 1451-1486, 2001
872001
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Artiklar 1–20