Suppression of Integrin α3β1 in Breast Cancer Cells Reduces Cyclooxygenase-2 Gene Expression and Inhibits Tumorigenesis, Invasion, and Cross-Talk to … K Mitchell, KB Svenson, WM Longmate, K Gkirtzimanaki, R Sadej, ... Cancer research 70 (15), 6359-6367, 2010 | 124 | 2010 |
CD151 regulates tumorigenesis by modulating the communication between tumor cells and endothelium R Sadej, H Romanska, G Baldwin, K Gkirtzimanaki, V Novitskaya, ... Molecular Cancer Research 7 (6), 787-798, 2009 | 124 | 2009 |
IFNα impairs autophagic degradation of mtDNA promoting autoreactivity of SLE monocytes in a STING-dependent fashion K Gkirtzimanaki, E Kabrani, D Nikoleri, A Polyzos, A Blanas, ... Cell reports 25 (4), 921-933. e5, 2018 | 118 | 2018 |
TPL2 kinase is a suppressor of lung carcinogenesis K Gkirtzimanaki, KK Gkouskou, U Oleksiewicz, G Nikolaidis, D Vyrla, ... Proceedings of the National Academy of Sciences 110 (16), E1470-E1479, 2013 | 57 | 2013 |
Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage E Goulielmaki, A Ioannidou, M Tsekrekou, K Stratigi, IK Poutakidou, ... Nature Communications 11 (1), 42, 2020 | 56 | 2020 |
R-loops trigger the release of cytoplasmic ssDNAs leading to chronic inflammation upon DNA damage O Chatzidoukaki, K Stratigi, E Goulielmaki, G Niotis, A Akalestou-Clocher, ... Science advances 7 (47), eabj5769, 2021 | 42 | 2021 |
NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE S Georgakis, K Gkirtzimanaki, G Papadaki, H Gakiopoulou, E Drakos, ... JCI insight 6 (21), 2021 | 41 | 2021 |
Enhanced therapeutic anti-tumor immunity induced by co-administration of 5-fluorouracil and adenovirus expressing CD40 ligand L Liljenfeldt, K Gkirtzimanaki, D Vyrla, E Svensson, ASI Loskog, ... Cancer Immunology, Immunotherapy 63, 273-282, 2014 | 27 | 2014 |
Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage ES Arvanitaki, E Goulielmaki, K Gkirtzimanaki, G Niotis, E Tsakani, ... Proceedings of the National Academy of Sciences 121 (17), e2317402121, 2024 | 8 | 2024 |
P107 Interferon-induced metabolic perturbations shape the inflammatory status of human monocytes: implications for innovative therapeutic engineering in SLE autoimmunity C Stathopoulou, V Ntassis, A Banos, K Gkirtzimanaki, A Myridakis, ... Lupus Science & Medicine 7 (Suppl 1), 2020 | 1 | 2020 |
ERCC1-XPF Interacts with Topoisomerase IIβ to Facilitate the Repair of Activity-induced DNA Breaks G Chatzinikolaou, K Stratigi, K Agathangelou, M Tsekrekou, ... bioRxiv, 2020.01. 03.892703, 2020 | 1 | 2020 |
O003 Characterising the role of net-derived IL-33 in SLE pathogenesis S Georgakis, G Papadaki, I Gergianaki, C Adamichou, S Polia, ... Annals of the Rheumatic Diseases 77 (Suppl 1), A2-A2, 2018 | 1 | 2018 |
P17 Autophagy-based unconventional secretion of B cell activating factor (BAFF) by monocytes in Systemic Lupus Erythematosus (SLE) D Nikoleri, M Semitekolou, A Gkirtzimanaki, S Georgakis, P Verginis, ... Lupus Science & Medicine 11 (Suppl 1), 2024 | | 2024 |
Suggested searches E Axell, J Hu, M Lindberg, AJ Dear, L Ortigosa-Pascual, EA Andrzejewska, ... Perspective, 2024 | | 2024 |
DNA damage in tissue-resident macrophages leads to age-related neurodegeneration K Gkirtzimanaki, E Tsakani, E Arvanitaki, E Nenedaki, M Kefalogianni, ... | | 2021 |
AB0048 CHARACTERIZING THE ROLE OF NET-DERIVED IL-33 IN SLE PATHOGENESIS G Spiros, G Papadaki, E Drakos, C Giakopoulou, ML Eloranta, ... Annals of the Rheumatic Diseases 78 (Suppl 2), 1490-1490, 2019 | | 2019 |
08.31 Unravelling the role of il33/st2l axis on sustained ifn-a production in systemic lupus erythematosus S Georgakis, G Papadaki, I Gergianaki, P Sidiropoulos, P Verginis, ... Annals of the Rheumatic Diseases 76 (Suppl 1), A88-A88, 2017 | | 2017 |
IFN (ALPHA)-MEDIATED DEREGULATION OF MITOCHONDRIAL DNA CLEARANCE PROMOTES THE AUTOREACTIVE PHENOTYPE OF PERIPHERAL BLOOD MONOCYTES IN HUMAN SYSTEMIC LUPUS ERYTHEMATOSUS K Gkirtzimanaki, E Kabrani, A Mplanas, P Sidiropoulos, G Bertsias, ... CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 34 (4), S54-S54, 2016 | | 2016 |
A1. 23 IFNα mediated deregulation of mitochondrial DNA clearance as an inciting event for the development of SLE autoimmunity K Gkirtzimanaki, E Kabrani, A Mplanas, P Sidiropoulos, G Bertsias, ... Annals of the Rheumatic Diseases 75 (Suppl 1), A10-A10, 2016 | | 2016 |
Deregulated, IFNα driven autophagy shapes the phenotype of autoreactive SLE monocytes Gkirtzimanaki K, Kabrani E, Mplanas A Annals of Rheumatic Diseases, 2015 | | 2015 |