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Jay Horvat
Jay Horvat
university of newcastle
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Immunological decision‐making: how does the immune system decide to mount a helper T‐cell response?
GE Kaiko, JC Horvat, KW Beagley, PM Hansbro
Immunology 123 (3), 326-338, 2008
8422008
Role for NLRP3 inflammasome–mediated, IL-1β–dependent responses in severe, steroid-resistant asthma
RY Kim, JW Pinkerton, AT Essilfie, AAB Robertson, KJ Baines, AC Brown, ...
American journal of respiratory and critical care medicine 196 (3), 283-297, 2017
3692017
A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis
EL Beckett, RL Stevens, AG Jarnicki, RY Kim, I Hanish, NG Hansbro, ...
Journal of Allergy and Clinical Immunology 131 (3), 752-762. e7, 2013
2762013
Interferon-ε protects the female reproductive tract from viral and bacterial infection
KY Fung, NE Mangan, H Cumming, JC Horvat, JR Mayall, SA Stifter, ...
Science 339 (6123), 1088-1092, 2013
2472013
MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase–mediated suppression of histone deacetylase 2
RY Kim, JC Horvat, JW Pinkerton, MR Starkey, AT Essilfie, JR Mayall, ...
Journal of Allergy and Clinical Immunology 139 (2), 519-532, 2017
2042017
Haemophilus influenzae Infection Drives IL-17-Mediated Neutrophilic Allergic Airways Disease
AT Essilfie, JL Simpson, JC Horvat, JA Preston, ML Dunkley, PS Foster, ...
PLoS pathogens 7 (10), e1002244, 2011
1922011
Inflammasomes in the lung
JW Pinkerton, RY Kim, AAB Robertson, JA Hirota, LG Wood, DA Knight, ...
Molecular immunology 86, 44-55, 2017
1742017
Understanding the mechanisms of viral induced asthma: new therapeutic directions
NG Hansbro, JC Horvat, PA Wark, PM Hansbro
Pharmacology & therapeutics 117 (3), 313-353, 2008
1712008
Neonatal chlamydial infection induces mixed T-cell responses that drive allergic airway disease
JC Horvat, KW Beagley, MA Wade, JA Preston, NG Hansbro, DK Hickey, ...
American journal of respiratory and critical care medicine 176 (6), 556-564, 2007
1622007
Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma
AT Essilfie, JC Horvat, RY Kim, JR Mayall, JW Pinkerton, EL Beckett, ...
Thorax 70 (5), 458-467, 2015
1432015
Role of atypical bacterial infection of the lung in predisposition/protection of asthma
PM Hansbro, KW Beagley, JC Horvat, PG Gibson
Pharmacology & therapeutics 101 (3), 193-210, 2004
1392004
Mechanisms and treatments for severe, steroid‐resistant allergic airway disease and asthma
PM Hansbro, RY Kim, MR Starkey, C Donovan, K Dua, JR Mayall, G Liu, ...
Immunological reviews 278 (1), 41-62, 2017
1352017
Evidence for local and systemic immune activation in functional dyspepsia and the irritable bowel syndrome: a systematic review
G Burns, G Carroll, A Mathe, J Horvat, P Foster, MM Walker, NJ Talley, ...
Official journal of the American College of Gastroenterology| ACG 114 (3 …, 2019
1342019
Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases
G Liu, MA Cooley, AG Jarnicki, ACY Hsu, PM Nair, TJ Haw, M Fricker, ...
JCI insight 1 (9), 2016
1332016
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
MC Runtsch, S Angiari, A Hooftman, R Wadhwa, Y Zhang, Y Zheng, ...
Cell metabolism 34 (3), 487-501. e8, 2022
1292022
Early-life chlamydial lung infection enhances allergic airways disease through age-dependent differences in immunopathology
JC Horvat, MR Starkey, RY Kim, S Phipps, PG Gibson, KW Beagley, ...
Journal of allergy and clinical immunology 125 (3), 617-625. e6, 2010
1292010
Inflammasomes in COPD and neutrophilic asthma
RY Kim, JW Pinkerton, PG Gibson, MA Cooper, JC Horvat, PM Hansbro
Thorax 70 (12), 1199-1201, 2015
1262015
Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease
JC Horvat, MR Starkey, RY Kim, KW Beagley, JA Preston, PG Gibson, ...
The Journal of Immunology 184 (8), 4159-4169, 2010
1162010
Streptococcus pneumoniae infection suppresses allergic airways disease by inducing regulatory T-cells
JA Preston, AN Thorburn, MR Starkey, EL Beckett, JC Horvat, MA Wade, ...
European Respiratory Journal 37 (1), 53-64, 2011
1122011
Interleukin-13 promotes susceptibility to chlamydial infection of the respiratory and genital tracts
KL Asquith, JC Horvat, GE Kaiko, AJ Carey, KW Beagley, PM Hansbro, ...
PLoS pathogens 7 (5), e1001339, 2011
1062011
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Articles 1–20