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Paul Dobson
Paul Dobson
Scruffy Biotech Ltd
Verifierad e-postadress på manchester.ac.uk - Startsida
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A community-driven global reconstruction of human metabolism
I Thiele, N Swainston, RMT Fleming, A Hoppe, S Sahoo, MK Aurich, ...
Nature biotechnology 31 (5), 419, 2013
11712013
Distinguishing enzyme structures from non-enzymes without alignments
PD Dobson, AJ Doig
Journal of molecular biology 330 (4), 771-783, 2003
6982003
A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology
MJ Herrgård, N Swainston, P Dobson, WB Dunn, KY Arga, M Arvas, ...
Nature biotechnology 26 (10), 1155, 2008
6782008
Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?
PD Dobson, DB Kell
Nature reviews Drug discovery 7 (3), 205, 2008
5582008
Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics
M Brown, WB Dunn, P Dobson, Y Patel, CL Winder, S Francis-McIntyre, ...
Analyst 134 (7), 1322-1332, 2009
3132009
Recon 2.2: from reconstruction to model of human metabolism
N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ...
Metabolomics 12 (7), 109, 2016
3072016
Predicting enzyme class from protein structure without alignments
PD Dobson, AJ Doig
Journal of molecular biology 345 (1), 187-199, 2005
2072005
Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only
DB Kell, PD Dobson, SG Oliver
Drug discovery today 16 (15-16), 704-714, 2011
1982011
The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so
DB Kell, PD Dobson, E Bilsland, SG Oliver
Drug discovery today 18 (5-6), 218-239, 2013
1602013
‘Metabolite-likeness’ as a criterion in the design and selection of pharmaceutical drug libraries
PD Dobson, Y Patel, DB Kell
Drug Discovery Today 14 (1-2), 31-40, 2009
1482009
Further developments towards a genome-scale metabolic model of yeast
PD Dobson, K Smallbone, D Jameson, E Simeonidis, K Lanthaler, P Pir, ...
BMC Systems Biology 4 (1), 145, 2010
1402010
Integration of metabolic databases for the reconstruction of genome-scale metabolic networks
K Radrich, Y Tsuruoka, P Dobson, A Gevorgyan, N Swainston, G Baart, ...
BMC systems biology 4 (1), 114, 2010
1132010
Implications of the Dominant Role of Transporters in Drug Uptake by Cells (Supplementary Material)
PD Dobson, K Lanthaler, SG Oliver, DB Kell
Current topics in medicinal chemistry 9 (2), 163-181, 2009
992009
Prediction of protein function in the absence of significant sequence similarity
PD Dobson, YD Cai, BJ Stapley, AJ Doig
Current medicinal chemistry 11 (16), 2135-2142, 2004
742004
Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast
K Lanthaler, E Bilsland, PD Dobson, HJ Moss, P Pir, DB Kell, SG Oliver
BMC biology 9 (1), 70, 2011
702011
Length preferences and periodicity in β‐strands. Antiparallel edge β‐sheets are more likely to finish in non‐hydrogen bonded rings
S Penel, RG Morrison, PD Dobson, RJ Mortishire‐Smith, AJ Doig
Protein engineering 16 (12), 957-961, 2003
522003
Mining metabolites: extracting the yeast metabolome from the literature
C Nobata, PD Dobson, SA Iqbal, P Mendes, J Tsujii, DB Kell, ...
Metabolomics 7 (1), 94-101, 2011
512011
biochem4j: Integrated and extensible biochemical knowledge through graph databases
N Swainston, R Batista-Navarro, P Carbonell, PD Dobson, M Dunstan, ...
PLoS One 12 (7), e0179130, 2017
472017
The cellular uptake of pharmaceutical drugs is mainly carrier-mediated and is thus an issue not so much of biophysics but of systems biology
DB Kell, PD Dobson
Proc Int Beilstein Symposium on Systems Chemistry, 2009
252009
Text mining meets workflow: linking U-Compare with Taverna
Y Kano, P Dobson, M Nakanishi, J Tsujii, S Ananiadou
Bioinformatics 26 (19), 2486-2487, 2010
242010
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Artiklar 1–20