Crystal Mackall
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T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial
DW Lee, JN Kochenderfer, M Stetler-Stevenson, YK Cui, C Delbrook, ...
The Lancet 385 (9967), 517-528, 2015
Current concepts in the diagnosis and management of cytokine release syndrome
DW Lee, R Gardner, DL Porter, CU Louis, N Ahmed, M Jensen, SA Grupp, ...
Blood, The Journal of the American Society of Hematology 124 (2), 188-195, 2014
Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1
PF Robbins, RA Morgan, SA Feldman, JC Yang, RM Sherry, ME Dudley, ...
Journal of Clinical Oncology 29 (7), 917, 2011
4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors
AH Long, WM Haso, JF Shern, KM Wanhainen, M Murgai, M Ingaramo, ...
Nature medicine 21 (6), 581-590, 2015
Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy
CL Mackall, TA Fleisher, MR Brown, MP Andrich, CC Chen, IM Feuerstein, ...
New England Journal of Medicine 332 (3), 143-149, 1995
CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy
TJ Fry, NN Shah, RJ Orentas, M Stetler-Stevenson, CM Yuan, ...
Nature medicine 24 (1), 20-28, 2018
Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy
E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ...
Cancer discovery 5 (12), 1282-1295, 2015
Tumor antigen escape from CAR T-cell therapy
RG Majzner, CL Mackall
Cancer discovery 8 (10), 1219-1226, 2018
Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy
SL Highfill, Y Cui, AJ Giles, JP Smith, H Zhang, E Morse, RN Kaplan, ...
Science translational medicine 6 (237), 237ra67-237ra67, 2014
The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance
TJ Fry, CL Mackall
The Journal of Immunology 174 (11), 6571-6576, 2005
Anti-CD22–chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia
W Haso, DW Lee, NN Shah, M Stetler-Stevenson, CM Yuan, IH Pastan, ...
Blood, The Journal of the American Society of Hematology 121 (7), 1165-1174, 2013
Interleukin-7: from bench to clinic
TJ Fry, CL Mackall
Blood, The Journal of the American Society of Hematology 99 (11), 3892-3904, 2002
Harnessing the biology of IL-7 for therapeutic application
CL Mackall, TJ Fry, RE Gress
Nature Reviews Immunology 11 (5), 330-342, 2011
c-Jun overexpression in CAR T cells induces exhaustion resistance
RC Lynn, EW Weber, E Sotillo, D Gennert, P Xu, Z Good, H Anbunathan, ...
Nature 576 (7786), 293-300, 2019
Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets
C Sportès, FT Hakim, SA Memon, H Zhang, KS Chua, MR Brown, ...
The Journal of experimental medicine 205 (7), 1701-1714, 2008
A potential role for interleukin-7 in T-cell homeostasis
TJ Fry, E Connick, J Falloon, MM Lederman, DJ Liewehr, J Spritzler, ...
Blood, The Journal of the American Society of Hematology 97 (10), 2983-2990, 2001
IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells
SA Rosenberg, C Sportès, M Ahmadzadeh, TJ Fry, LT Ngo, SL Schwarz, ...
Journal of immunotherapy 29 (3), 313-319, 2006
Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing.
CL Mackall, CV Bare, LA Granger, SO Sharrow, JA Titus, RE Gress
Journal of immunology (Baltimore, Md.: 1950) 156 (12), 4609-4616, 1996
Distinctions Between CD8+ and CD4+ T-Cell Regenerative Pathways Result in Prolonged T-Cell Subset Imbalance After Intensive Chemotherapy
CL Mackall, TA Fleisher, MR Brown, MP Andrich, CC Chen, IM Feuerstein, ...
Blood, The Journal of the American Society of Hematology 89 (10), 3700-3707, 1997
Lymphocyte depletion during treatment with intensive chemotherapy for cancer
CL Mackall, TA Fleisher, MR Brown, IT Magrath, AT Shad, ME Horowitz, ...
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