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David J Wooten
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Quantifying drug combination synergy along potency and efficacy axes
CT Meyer, DJ Wooten, BB Paudel, J Bauer, KN Hardeman, D Westover, ...
Cell systems 8 (2), 97-108. e16, 2019
1502019
Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers
DJ Wooten, SM Groves, DR Tyson, Q Liu, JS Lim, R Albert, CF Lopez, ...
PLoS computational biology 15 (10), e1007343, 2019
852019
Novel hybrid phenotype revealed in small cell lung cancer by a transcription factor network model that can explain tumor heterogeneity
AR Udyavar, DJ Wooten, M Hoeksema, M Bansal, A Califano, L Estrada, ...
Cancer Research 77 (5), 1063-1074, 2017
742017
Charting the fragmented landscape of drug synergy
CT Meyer, DJ Wooten, CF Lopez, V Quaranta
Trends in pharmacological sciences 41 (4), 266-280, 2020
622020
MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery
DJ Wooten, CT Meyer, ALR Lubbock, V Quaranta, CF Lopez
Nature communications 12 (1), 4607, 2021
512021
Ventricular-subventricular zone contact by glioblastoma is not associated with molecular signatures in bulk tumor data
AM Mistry, DJ Wooten, LT Davis, BC Mobley, V Quaranta, RA Ihrie
Scientific Reports 9 (1), 1842, 2019
332019
synergy: a Python library for calculating, analyzing and visualizing drug combination synergy
DJ Wooten, R Albert
Bioinformatics 37 (10), 1473-1474, 2021
302021
Mathematical models of cell phenotype regulation and reprogramming: Make cancer cells sensitive again!
DJ Wooten, V Quaranta
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1867 (2), 167-175, 2017
282017
Mathematical modeling of the Candida albicans yeast to hyphal transition reveals novel control strategies
DJ Wooten, JGT Zaņudo, D Murrugarra, AM Perry, A Dongari-Bagtzoglou, ...
PLoS computational biology 17 (3), e1008690, 2021
192021
Data-driven math model of FLT3-ITD acute myeloid leukemia reveals potential therapeutic targets
DJ Wooten, M Gebru, HG Wang, R Albert
Journal of personalized medicine 11 (3), 193, 2021
102021
A consensus framework unifies multi-drug synergy metrics
DJ Wooten, CT Meyer, V Quaranta, C Lopez
BioRxiv, 683433, 2019
102019
Selenium induces pancreatic cancer cell death alone and in combination with gemcitabine
DJ Wooten, I Sinha, R Sinha
Biomedicines 10 (1), 149, 2022
62022
Quantifying drug combination synergy along potency and efficacy axes. Cell Syst. 2019; 8: 97–108. e16
CT Meyer, DJ Wooten, BB Paudel, J Bauer, KN Hardeman, D Westover, ...
6
Correction: Novel Hybrid. Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model. That Can Explain Tumor Heterogeneity
AR Udyavar, DJ Wooten, M Hoeksema, M Bansal, A Califano, L Estrada, ...
Cancer Res 79 (1014), 10.1158, 2019
32019
Small cell lung cancer subtypes identified by systems-level modeling of transcription factor networks
D Wooten, S Maddox, D Tyson, Q Liu, JS Lim, J Sage, V Quaranta
Preprint at bioRxiv https://www. biorxiv. org/content/10.1101/506402v2, 2018
22018
A transcription factor network model explains heterogeneity and reveals a novel hybrid phenotype in Small-Cell Lung Cancer
AR Udyavar, DJ Wooten, M Hoeksema, M Bansal, A Califano, L Estrada, ...
Cancer research 77 (5), 1063, 2017
12017
Methods for evaluating therapeutic benefit of combination therapies
CT Meyer, V Quaranta, LA Harris, BB Paudel, DJ Wooten, L Audoly
US Patent App. 17/180,280, 2021
2021
Yutong Sha1, 2, Shuxiong Wang1, Federico Bocci1, 2, Peijie Zhou1* and Qing Nie1, 2, 3
A Sharma, W Wang, DJ Wooten, FF Clos, P Zhou, Q Nie, Y Sha, S Wang, ...
Non-Genetic Heterogeneity in Development and Disease, 2021
2021
Synergy
DJ Wooten, R Albert
2021
PATH-34. VENTRICULAR-SUBVENTRICULAR ZONE CONTACT BY GLIOBLASTOMA IS NOT ASSOCIATED WITH MOLECULAR SIGNATURES IN BULK TUMOR DATA
A Mistry, D Wooten, B Mobley, V Quaranta, R Ihrie
Neuro-Oncology 20 (Suppl 6), vi166, 2018
2018
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Articles 1–20