Följ
Qi Zhao
Qi Zhao
Enrich Biosystems Inc.
Verifierad e-postadress på enrichtherapeutics.com
Titel
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Design of wide-spectrum inhibitors targeting coronavirus main proteases
H Yang, W Xie, X Xue, K Yang, J Ma, W Liang, Q Zhao, Z Zhou, D Pei, ...
PLoS biology 3 (10), e324, 2005
7472005
Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design
X Xue, H Yu, H Yang, F Xue, Z Wu, W Shen, J Li, Z Zhou, Y Ding, Q Zhao, ...
Journal of virology 82 (5), 2515-2527, 2008
4532008
Production of authentic SARS-CoV Mpro with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction
X Xue, H Yang, W Shen, Q Zhao, J Li, K Yang, C Chen, Y Jin, M Bartlam, ...
Journal of molecular biology 366 (3), 965-975, 2007
2412007
Structural basis of cellular dNTP regulation by SAMHD1
X Ji, C Tang, Q Zhao, W Wang, Y Xiong
Proceedings of the National Academy of Sciences 111 (41), E4305-E4314, 2014
1482014
Neu-Laxova syndrome, an inborn error of serine metabolism, is caused by mutations in PHGDH
R Shaheen, Z Rahbeeni, A Alhashem, E Faqeih, Q Zhao, Y Xiong, ...
The American Journal of Human Genetics 94 (6), 898-904, 2014
1102014
Structure of the main protease from a global infectious human coronavirus, HCoV-HKU1
Q Zhao, S Li, F Xue, Y Zou, C Chen, M Bartlam, Z Rao
Journal of virology 82 (17), 8647-8655, 2008
1002008
Structural basis of Zika virus helicase in recognizing its substrates
H Tian, X Ji, X Yang, Z Zhang, Z Lu, K Yang, C Chen, Q Zhao, H Chi, Z Mu, ...
Protein & cell 7 (8), 562-570, 2016
872016
Structural insight into HIV-1 capsid recognition by rhesus TRIM5α
H Yang, X Ji, G Zhao, J Ning, Q Zhao, C Aiken, AM Gronenborn, P Zhang, ...
Proceedings of the National Academy of Sciences 109 (45), 18372-18377, 2012
782012
HIV suppression by host restriction factors and viral immune evasion
X Jia, Q Zhao, Y Xiong
Current opinion in structural biology 31, 106-114, 2015
702015
Crystal structures of two coronavirus ADP-ribose-1 ″-monophosphatases and their complexes with ADP-ribose: a systematic structural analysis of the viral ADRP domain
Y Xu, L Cong, C Chen, L Wei, Q Zhao, X Xu, Y Ma, M Bartlam, Z Rao
Journal of virology 83 (2), 1083-1092, 2009
622009
Structural insights into 5′ flap DNA unwinding and incision by the human FAN1 dimer
Q Zhao, X Xue, S Longerich, P Sung, Y Xiong
Nature communications 5 (1), 5726, 2014
412014
Study of Mendelian forms of Crohn's disease in Saudi Arabia reveals novel risk loci and alleles
N Patel, MI El Mouzan, SM Al-Mayouf, N Adly, JY Mohamed, ...
Gut 63 (11), 1831-1832, 2014
342014
Structural insight into the Zika virus capsid encapsulating the viral genome
T Li, Q Zhao, X Yang, C Chen, K Yang, C Wu, T Zhang, Y Duan, X Xue, ...
Cell research 28 (4), 497-499, 2018
332018
The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes
Q Zhao, D Saro, A Sachpatzidis, TR Singh, D Schlingman, XF Zheng, ...
Nature communications 5 (1), 2987, 2014
312014
A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro
D Wang, C Chen, S Liu, H Zhou, K Yang, Q Zhao, X Ji, C Chen, W Xie, ...
Scientific reports 7 (1), 42580, 2017
302017
Michael acceptor-based peptidomimetic inhibitor of main protease from porcine epidemic diarrhea virus
F Wang, C Chen, K Yang, Y Xu, X Liu, F Gao, H Liu, X Chen, Q Zhao, ...
Journal of Medicinal Chemistry 60 (7), 3212-3216, 2017
262017
Recent developments on coronavirus main protease/3C like protease inhibitors
Q Zhao, E Weber, H Yang
Recent patents on anti-infective drug discovery 8 (2), 150-156, 2013
252013
Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59
X Xu, Z Lou, Y Ma, X Chen, Z Yang, X Tong, Q Zhao, Y Xu, H Deng, ...
PLoS One 4 (7), e6217, 2009
252009
New nsp8 isoform suggests mechanism for tuning viral RNA synthesis
S Li, Q Zhao, Y Zhang, Y Zhang, M Bartlam, X Li, Z Rao
Protein & cell 1 (2), 198-204, 2010
232010
Mechanism of ATP hydrolysis by the Zika virus helicase
X Yang, C Chen, H Tian, H Chi, Z Mu, T Zhang, K Yang, Q Zhao, X Liu, ...
The FASEB Journal 32 (10), 5250-5257, 2018
202018
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Artiklar 1–20