Design of wide-spectrum inhibitors targeting coronavirus main proteases H Yang, W Xie, X Xue, K Yang, J Ma, W Liang, Q Zhao, Z Zhou, D Pei, ... PLoS biology 3 (10), e324, 2005 | 747 | 2005 |
Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design X Xue, H Yu, H Yang, F Xue, Z Wu, W Shen, J Li, Z Zhou, Y Ding, Q Zhao, ... Journal of virology 82 (5), 2515-2527, 2008 | 453 | 2008 |
Production of authentic SARS-CoV Mpro with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction X Xue, H Yang, W Shen, Q Zhao, J Li, K Yang, C Chen, Y Jin, M Bartlam, ... Journal of molecular biology 366 (3), 965-975, 2007 | 241 | 2007 |
Structural basis of cellular dNTP regulation by SAMHD1 X Ji, C Tang, Q Zhao, W Wang, Y Xiong Proceedings of the National Academy of Sciences 111 (41), E4305-E4314, 2014 | 148 | 2014 |
Neu-Laxova syndrome, an inborn error of serine metabolism, is caused by mutations in PHGDH R Shaheen, Z Rahbeeni, A Alhashem, E Faqeih, Q Zhao, Y Xiong, ... The American Journal of Human Genetics 94 (6), 898-904, 2014 | 110 | 2014 |
Structure of the main protease from a global infectious human coronavirus, HCoV-HKU1 Q Zhao, S Li, F Xue, Y Zou, C Chen, M Bartlam, Z Rao Journal of virology 82 (17), 8647-8655, 2008 | 100 | 2008 |
Structural basis of Zika virus helicase in recognizing its substrates H Tian, X Ji, X Yang, Z Zhang, Z Lu, K Yang, C Chen, Q Zhao, H Chi, Z Mu, ... Protein & cell 7 (8), 562-570, 2016 | 87 | 2016 |
Structural insight into HIV-1 capsid recognition by rhesus TRIM5α H Yang, X Ji, G Zhao, J Ning, Q Zhao, C Aiken, AM Gronenborn, P Zhang, ... Proceedings of the National Academy of Sciences 109 (45), 18372-18377, 2012 | 78 | 2012 |
HIV suppression by host restriction factors and viral immune evasion X Jia, Q Zhao, Y Xiong Current opinion in structural biology 31, 106-114, 2015 | 70 | 2015 |
Crystal structures of two coronavirus ADP-ribose-1 ″-monophosphatases and their complexes with ADP-ribose: a systematic structural analysis of the viral ADRP domain Y Xu, L Cong, C Chen, L Wei, Q Zhao, X Xu, Y Ma, M Bartlam, Z Rao Journal of virology 83 (2), 1083-1092, 2009 | 62 | 2009 |
Structural insights into 5′ flap DNA unwinding and incision by the human FAN1 dimer Q Zhao, X Xue, S Longerich, P Sung, Y Xiong Nature communications 5 (1), 5726, 2014 | 41 | 2014 |
Study of Mendelian forms of Crohn's disease in Saudi Arabia reveals novel risk loci and alleles N Patel, MI El Mouzan, SM Al-Mayouf, N Adly, JY Mohamed, ... Gut 63 (11), 1831-1832, 2014 | 34 | 2014 |
Structural insight into the Zika virus capsid encapsulating the viral genome T Li, Q Zhao, X Yang, C Chen, K Yang, C Wu, T Zhang, Y Duan, X Xue, ... Cell research 28 (4), 497-499, 2018 | 33 | 2018 |
The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes Q Zhao, D Saro, A Sachpatzidis, TR Singh, D Schlingman, XF Zheng, ... Nature communications 5 (1), 2987, 2014 | 31 | 2014 |
A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro D Wang, C Chen, S Liu, H Zhou, K Yang, Q Zhao, X Ji, C Chen, W Xie, ... Scientific reports 7 (1), 42580, 2017 | 30 | 2017 |
Michael acceptor-based peptidomimetic inhibitor of main protease from porcine epidemic diarrhea virus F Wang, C Chen, K Yang, Y Xu, X Liu, F Gao, H Liu, X Chen, Q Zhao, ... Journal of Medicinal Chemistry 60 (7), 3212-3216, 2017 | 26 | 2017 |
Recent developments on coronavirus main protease/3C like protease inhibitors Q Zhao, E Weber, H Yang Recent patents on anti-infective drug discovery 8 (2), 150-156, 2013 | 25 | 2013 |
Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59 X Xu, Z Lou, Y Ma, X Chen, Z Yang, X Tong, Q Zhao, Y Xu, H Deng, ... PLoS One 4 (7), e6217, 2009 | 25 | 2009 |
New nsp8 isoform suggests mechanism for tuning viral RNA synthesis S Li, Q Zhao, Y Zhang, Y Zhang, M Bartlam, X Li, Z Rao Protein & cell 1 (2), 198-204, 2010 | 23 | 2010 |
Mechanism of ATP hydrolysis by the Zika virus helicase X Yang, C Chen, H Tian, H Chi, Z Mu, T Zhang, K Yang, Q Zhao, X Liu, ... The FASEB Journal 32 (10), 5250-5257, 2018 | 20 | 2018 |