HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease V Benoy, L Van Helleputte, R Prior, C d’Ydewalle, W Haeck, N Geens, ... Brain 141 (3), 673-687, 2018 | 105 | 2018 |
Defective axonal transport: a common pathological mechanism in inherited and acquired peripheral neuropathies R Prior, L Van Helleputte, V Benoy, L Van Den Bosch Neurobiology of disease 105, 300-320, 2017 | 105 | 2017 |
Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model E Rossaert, E Pollari, T Jaspers, L Van Helleputte, M Jarpe, ... Acta neuropathologica communications 7, 1-19, 2019 | 75 | 2019 |
The role of histone deacetylase 6 (HDAC6) in neurodegeneration LV Helleputte, V Benoy, L Van Den Bosch Research and Reports in Biology, 1-13, 2014 | 71 | 2014 |
Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth L Van Helleputte, M Kater, DP Cook, C Eykens, E Rossaert, W Haeck, ... Neurobiology of Disease 111, 59-69, 2018 | 59 | 2018 |
Testosterone boosts physical activity in male mice via dopaminergic pathways F Jardí, MR Laurent, N Kim, R Khalil, D De Bundel, A Van Eeckhaut, ... Scientific reports 8 (1), 957, 2018 | 57 | 2018 |
HDAC6 as a potential therapeutic target for peripheral nerve disorders R Prior, L Van Helleputte, YE Klingl, L Van Den Bosch Expert Opinion on Therapeutic Targets 22 (12), 993-1007, 2018 | 31 | 2018 |
Genetic ablation of phospholipase C delta 1 increases survival in SOD1G93A mice KA Staats, L Van Helleputte, AR Jones, A Bento-Abreu, A Van Hoecke, ... Neurobiology of Disease 60, 11-17, 2013 | 23 | 2013 |
Pyrimidine hydroxy amide compounds for treating peripheral neuropathy MB Jarpe, L Van Den Bosch, V Benoy, L Van Helleputte US Patent App. 14/959,317, 2016 | 13 | 2016 |
Impact of prolonged sepsis on neural and muscular components of muscle contractions in a mouse model C Goossens, R Weckx, S Derde, L Van Helleputte, D Schneidereit, ... Journal of Cachexia, Sarcopenia and Muscle 12 (2), 443-455, 2021 | 8 | 2021 |
Transcriptional upregulation of myelin components in spontaneous myelin basic protein-deficient mice KA Staats, D Pombal, S Schönefeldt, L Van Helleputte, H Maurin, ... Brain research 1606, 125-132, 2015 | 6 | 2015 |
PhAc-ALGP-Dox, a novel anticancer prodrug with targeted activation and improved therapeutic index A Casazza, L Van Helleputte, B Van Renterghem, P Pokreisz, N De Geest, ... Molecular Cancer Therapeutics 21 (4), 568-581, 2022 | 5 | 2022 |
Testosterone boosts physical activity in male mice via dopaminergic pathways. Sci. Rep. 8, 957 F Jardí, MR Laurent, N Kim, R Khalil, D De Bundel, A Van Eeckhaut, ... | 5 | 2018 |
C-kit is important for SOD1G93A mouse survival independent of mast cells KA Staats, S Schönefeldt, L Van Helleputte, M Van Rillaer, Y Lampi, ... Neuroscience 301, 415-420, 2015 | 5 | 2015 |
Inhibition of histone deacetylase 6 (HDAC6) as a therapeutic strategy in chemotherapy-induced peripheral neuropathies L Van Helleputte Journal Of The Peripheral Nervous System 20 (2), 2018 | 3 | 2018 |
Histone deacetylase 3 inhibition improves Schwann cell lipid metabolism and myelination in Charcot-Marie-Tooth disease 1A R Prior, S Verschoren, D Van den Biggelaar, K Vints, N Hersmus, ... Journal Of The Peripheral Nervous System 25 (4), 567-567, 2020 | | 2020 |
Therapeutic effects of HDAC6 inhibitors in models of inherited and acquired neuropathies L Van den Bosch, V Benoy, L Van Helleputte, R Prior Journal Of The Peripheral Nervous System 23 (4), 328-328, 2018 | | 2018 |
INHIBITION OF HISTONE DEACETYLASE 6 (HDAC6) PROTECTS AGAINST VINCRISTINE-INDUCED PERIPHERNAL NEUROPATHIES AND INHIBITS TUMOR GROWTH L Van Helleputte, M Kater, D Cook, W Haeck, T Jaspers, N Geens, ... Journal Of The Peripheral Nervous System 22 (3), 402-402, 2017 | | 2017 |
PHARMACOLOGICAL INHIBITION OF HDAC6 IS BENEFICIAL IN A MOUSE MODEL OF DISTAL HEREDITARY MOTOR NEUROPATHY (DISTAL HMN) V Benoy, C d'Ydewalle, L Van Helleputte, J Krishnan, P Van Damme, ... Journal Of The Peripheral Nervous System 18, 12-12, 2013 | | 2013 |