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Lawrence Van Helleputte, PhD
Lawrence Van Helleputte, PhD
Associatet @ Fund+
Verifierad e-postadress på cobiores.be
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Defective axonal transport: a common pathological mechanism in inherited and acquired peripheral neuropathies
R Prior, L Van Helleputte, V Benoy, L Van Den Bosch
Neurobiology of disease 105, 300-320, 2017
1052017
HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease
V Benoy, L Van Helleputte, R Prior, C d’Ydewalle, W Haeck, N Geens, ...
Brain 141 (3), 673-687, 2018
1042018
Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model
E Rossaert, E Pollari, T Jaspers, L Van Helleputte, M Jarpe, ...
Acta neuropathologica communications 7, 1-19, 2019
742019
The role of histone deacetylase 6 (HDAC6) in neurodegeneration
LV Helleputte, V Benoy, L Van Den Bosch
Research and Reports in Biology, 1-13, 2014
712014
Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth
L Van Helleputte, M Kater, DP Cook, C Eykens, E Rossaert, W Haeck, ...
Neurobiology of Disease 111, 59-69, 2018
592018
Testosterone boosts physical activity in male mice via dopaminergic pathways
F Jardí, MR Laurent, N Kim, R Khalil, D De Bundel, A Van Eeckhaut, ...
Scientific reports 8 (1), 957, 2018
572018
HDAC6 as a potential therapeutic target for peripheral nerve disorders
R Prior, L Van Helleputte, YE Klingl, L Van Den Bosch
Expert Opinion on Therapeutic Targets 22 (12), 993-1007, 2018
312018
Genetic ablation of phospholipase C delta 1 increases survival in SOD1G93A mice
KA Staats, L Van Helleputte, AR Jones, A Bento-Abreu, A Van Hoecke, ...
Neurobiology of Disease 60, 11-17, 2013
232013
Pyrimidine hydroxy amide compounds for treating peripheral neuropathy
MB Jarpe, L Van Den Bosch, V Benoy, L Van Helleputte
US Patent App. 14/959,317, 2016
132016
Impact of prolonged sepsis on neural and muscular components of muscle contractions in a mouse model
C Goossens, R Weckx, S Derde, L Van Helleputte, D Schneidereit, ...
Journal of Cachexia, Sarcopenia and Muscle 12 (2), 443-455, 2021
82021
Transcriptional upregulation of myelin components in spontaneous myelin basic protein-deficient mice
KA Staats, D Pombal, S Schönefeldt, L Van Helleputte, H Maurin, ...
Brain research 1606, 125-132, 2015
62015
PhAc-ALGP-Dox, a novel anticancer prodrug with targeted activation and improved therapeutic index
A Casazza, L Van Helleputte, B Van Renterghem, P Pokreisz, N De Geest, ...
Molecular Cancer Therapeutics 21 (4), 568-581, 2022
52022
Testosterone boosts physical activity in male mice via dopaminergic pathways. Sci. Rep. 8, 957
F Jardí, MR Laurent, N Kim, R Khalil, D De Bundel, A Van Eeckhaut, ...
52018
C-kit is important for SOD1G93A mouse survival independent of mast cells
KA Staats, S Schönefeldt, L Van Helleputte, M Van Rillaer, Y Lampi, ...
Neuroscience 301, 415-420, 2015
52015
Inhibition of histone deacetylase 6 (HDAC6) as a therapeutic strategy in chemotherapy-induced peripheral neuropathies
L Van Helleputte
Journal Of The Peripheral Nervous System 20 (2), 2018
32018
Histone deacetylase 3 inhibition improves Schwann cell lipid metabolism and myelination in Charcot-Marie-Tooth disease 1A
R Prior, S Verschoren, D Van den Biggelaar, K Vints, N Hersmus, ...
Journal Of The Peripheral Nervous System 25 (4), 567-567, 2020
2020
Therapeutic effects of HDAC6 inhibitors in models of inherited and acquired neuropathies
L Van den Bosch, V Benoy, L Van Helleputte, R Prior
Journal Of The Peripheral Nervous System 23 (4), 328-328, 2018
2018
INHIBITION OF HISTONE DEACETYLASE 6 (HDAC6) PROTECTS AGAINST VINCRISTINE-INDUCED PERIPHERNAL NEUROPATHIES AND INHIBITS TUMOR GROWTH
L Van Helleputte, M Kater, D Cook, W Haeck, T Jaspers, N Geens, ...
Journal Of The Peripheral Nervous System 22 (3), 402-402, 2017
2017
PHARMACOLOGICAL INHIBITION OF HDAC6 IS BENEFICIAL IN A MOUSE MODEL OF DISTAL HEREDITARY MOTOR NEUROPATHY (DISTAL HMN)
V Benoy, C d'Ydewalle, L Van Helleputte, J Krishnan, P Van Damme, ...
Journal Of The Peripheral Nervous System 18, 12-12, 2013
2013
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Artiklar 1–19