| Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA AS Tan, JW Baty, LF Dong, A Bezawork-Geleta, B Endaya, J Goodwin, ... Cell metabolism 21 (1), 81-94, 2015 | 707 | 2015 |
| The serine protease TMPRSS6 is required to sense iron deficiency X Du, E She, T Gelbart, J Truksa, P Lee, Y Xia, K Khovananth, S Mudd, ... Science 320 (5879), 1088-1092, 2008 | 689 | 2008 |
| Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6 J Truksa, H Peng, P Lee, E Beutler Proceedings of the National Academy of Sciences 103 (27), 10289-10293, 2006 | 408 | 2006 |
| Classification of mitocans, anti-cancer drugs acting on mitochondria J Neuzil, LF Dong, J Rohlena, J Truksa, SJ Ralph Mitochondrion 13 (3), 199-208, 2013 | 265 | 2013 |
| Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells LF Dong, J Kovarova, M Bajzikova, A Bezawork-Geleta, D Svec, ... elife 6, e22187, 2017 | 256 | 2017 |
| Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II LF Dong, VJA Jameson, D Tilly, J Cerny, E Mahdavian, ... Journal of Biological Chemistry 286 (5), 3717-3728, 2011 | 232 | 2011 |
| Reactivation of dihydroorotate dehydrogenase-driven pyrimidine biosynthesis restores tumor growth of respiration-deficient cancer cells M Bajzikova, J Kovarova, AR Coelho, S Boukalova, S Oh, K Rohlenova, ... Cell metabolism 29 (2), 399-416. e10, 2019 | 208 | 2019 |
| Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness J Truksa, P Lee, E Beutler Blood, The Journal of the American Society of Hematology 113 (3), 688-695, 2009 | 138 | 2009 |
| Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy LF Dong, VJA Jameson, D Tilly, L Prochazka, J Rohlena, K Valis, J Truksa, ... Free Radical Biology and Medicine 50 (11), 1546-1555, 2011 | 124 | 2011 |
| Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner K Valis, L Prochazka, E Boura, J Chladova, T Obsil, J Rohlena, J Truksa, ... Cancer research 71 (3), 946-954, 2011 | 113 | 2011 |
| Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer K Rohlenova, K Sachaphibulkij, J Stursa, A Bezawork-Geleta, J Blecha, ... Antioxidants & redox signaling 26 (2), 84-103, 2017 | 109 | 2017 |
| MicroRNA-126 suppresses mesothelioma malignancy by targeting IRS1 and interfering with the mitochondrial function M Tomasetti, L Nocchi, S Staffolani, N Manzella, M Amati, J Goodwin, ... Antioxidants & redox signaling 21 (15), 2109-2125, 2014 | 107 | 2014 |
| Polymorphisms and mutations of human TMPRSS6 in iron deficiency anemia E Beutler, C Van Geet, D te Loo, T Gelbart, K Crain, J Truksa, PL Lee Blood Cells, Molecules, and Diseases 44 (1), 16-21, 2010 | 87 | 2010 |
| Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism Z Rychtarcikova, S Lettlova, V Tomkova, V Korenkova, L Langerova, ... Oncotarget 8 (4), 6376, 2017 | 81 | 2017 |
| Different regulatory elements are required for response of hepcidin to interleukin‐6 and bone morphogenetic proteins 4 and 9 J Truksa, H Peng, P Lee, E Beutler British journal of haematology 139 (1), 138-147, 2007 | 79 | 2007 |
| Suppression of the hepcidin‐encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase‐2/TMPRSS6 J Truksa, T Gelbart, H Peng, E Beutler, B Beutler, P Lee British journal of haematology 147 (4), 571-581, 2009 | 67 | 2009 |
| Targeting mitochondrial iron metabolism suppresses tumor growth and metastasis by inducing mitochondrial dysfunction and mitophagy C Sandoval-Acuna, N Torrealba, V Tomkova, SB Jadhav, K Blazkova, ... Cancer Research 81 (9), 2289-2303, 2021 | 61 | 2021 |
| MicroRNA-126 induces autophagy by altering cell metabolism in malignant mesothelioma M Tomasetti, F Monaco, N Manzella, J Rohlena, K Rohlenova, ... Oncotarget 7 (24), 36338, 2016 | 54 | 2016 |
| Mitochondrially targeted vitamin E succinate modulates expression of mitochondrial DNA transcripts and mitochondrial biogenesis J Truksa, LF Dong, J Rohlena, J Stursa, M Vondrusova, J Goodwin, ... Antioxidants & redox signaling 22 (11), 883-900, 2015 | 50 | 2015 |
| Mitochondrial fragmentation, elevated mitochondrial superoxide and respiratory supercomplexes disassembly is connected with the tamoxifen-resistant phenotype of breast cancer cells V Tomková, C Sandoval-Acuña, N Torrealba, J Truksa Free Radical Biology and Medicine 143, 510-521, 2019 | 47 | 2019 |
Lan-feng DongResearch Fellow, Griffith UniversityVerifierad e-postadress på griffith.edu.au
