Mackensen, Andreas
Mackensen, Andreas
Dept. of Hematology/Oncology, University of Erlangen, Germany
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Inhibitory effect of tumor cell–derived lactic acid on human T cells
K Fischer, P Hoffmann, S Voelkl, N Meidenbauer, J Ammer, M Edinger, ...
Blood 109 (9), 3812-3819, 2007
LDHA-associated lactic acid production blunts tumor immunosurveillance by T and NK cells
A Brand, K Singer, GE Koehl, M Kolitzus, G Schoenhammer, A Thiel, ...
Cell metabolism 24 (5), 657-671, 2016
Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: implications for tumor immunotherapy
C Blank, TF Gajewski, A Mackensen
Cancer Immunology, Immunotherapy 54, 307-314, 2005
Tumor-derived lactic acid modulates dendritic cell activation and antigen expression
E Gottfried, LA Kunz-Schughart, S Ebner, W Mueller-Klieser, S Hoves, ...
Blood 107 (5), 2013-2021, 2006
Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion
C Blank, A Mackensen
Cancer immunology, immunotherapy 56, 739-745, 2007
Phase I study in melanoma patients of a vaccine with peptide‐pulsed dendritic cells generated in vitro from CD34+ hematopoietic progenitor cells
A Mackensen, B Herbst, JL Chen, G Köhler, C Noppen, W Herr, ...
International journal of cancer 86 (3), 385-392, 2000
Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance
A Zippelius, P Batard, V Rubio-Godoy, G Bioley, D Liénard, F Lejeune, ...
Cancer research 64 (8), 2865-2873, 2004
Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2 …
C Röllig, H Serve, A Hüttmann, R Noppeney, C Müller-Tidow, U Krug, ...
The lancet oncology 16 (16), 1691-1699, 2015
Blockade of PD‐L1 (B7‐H1) augments human tumor‐specific T cell responses in vitro
C Blank, J Kuball, S Voelkl, H Wiendl, B Becker, B Walter, O Majdic, ...
International journal of cancer 119 (2), 317-327, 2006
Bispecific T-cell engager (BiTE) antibody construct blinatumomab for the treatment of patients with relapsed/refractory non-Hodgkin lymphoma: final results from a phase I study
ME Goebeler, S Knop, A Viardot, P Kufer, MS Topp, H Einsele, ...
Journal of Clinical Oncology 34 (10), 1104-1111, 2016
Phase I study of adoptive T-cell therapy using antigen-specific CD8+ T cells for the treatment of patients with metastatic melanoma
A Mackensen, N Meidenbauer, S Vogl, M Laumer, J Berger, R Andreesen
Journal of Clinical Oncology 24 (31), 5060-5069, 2006
Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig–coated artificial antigen-presenting cells
M Oelke, MV Maus, D Didiano, CH June, A Mackensen, JP Schneck
Nature medicine 9 (5), 619-625, 2003
Isolation and characterization of human antigen-specific TCRαβ+ CD4-CD8-double-negative regulatory T cells
K Fischer, S Voelkl, J Heymann, GK Przybylski, K Mondal, M Laumer, ...
Blood 105 (7), 2828-2835, 2005
Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus
A Mackensen, F Müller, D Mougiakakos, S Böltz, A Wilhelm, M Aigner, ...
Nature medicine 28 (10), 2124-2132, 2022
Malignant melanoma S3‐guideline “diagnosis, therapy and follow‐up of melanoma”
A Pflugfelder, C Kochs, A Blum, M Capellaro, C Czeschik, T Dettenborn, ...
JDDG: Journal der Deutschen Dermatologischen Gesellschaft 11 (s6), 1-116, 2013
Presence of IgE antibodies to bovine serum albumin in a patient developing anaphylaxis after vaccination with human peptide-pulsed dendritic cells
A Mackensen, R Dräger, M Schlesier, R Mertelsmann, A Lindemann
Cancer Immunology, Immunotherapy 49, 152-156, 2000
CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs
R Jitschin, M Braun, M Büttner, K Dettmer-Wilde, J Bricks, J Berger, ...
Blood, The Journal of the American Society of Hematology 124 (5), 750-760, 2014
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells
NR Mathew, F Baumgartner, L Braun, D O'Sullivan, S Thomas, ...
Nature medicine 24 (3), 282-291, 2018
Mitochondrial metabolism contributes to oxidative stress and reveals therapeutic targets in chronic lymphocytic leukemia
R Jitschin, AD Hofmann, H Bruns, A Gießl, J Bricks, J Berger, D Saul, ...
Blood, The Journal of the American Society of Hematology 123 (17), 2663-2672, 2014
Direct evidence to support the immunosurveillance concept in a human regressive melanoma.
A Mackensen, G Carcelain, S Viel, MC Raynal, H Michalaki, F Triebel, ...
The Journal of clinical investigation 93 (4), 1397-1402, 1994
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