| Chemical manipulation of hsp70 ATPase activity regulates tau stability UK Jinwal, Y Miyata, J Koren, JR Jones, JH Trotter, L Chang, J O'Leary, ... Journal of neuroscience 29 (39), 12079-12088, 2009 | 271 | 2009 |
| The epichaperome is an integrated chaperome network that facilitates tumour survival A Rodina, T Wang, P Yan, EDG Gomes, MPS Dunphy, N Pillarsetty, ... Nature 538 (7625), 397-401, 2016 | 247 | 2016 |
| Akt and CHIP coregulate tau degradation through coordinated interactions CA Dickey, J Koren, YJ Zhang, Y Xu, UK Jinwal, MJ Birnbaum, B Monks, ... Proceedings of the National Academy of Sciences 105 (9), 3622-3627, 2008 | 243 | 2008 |
| The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules UK Jinwal, J Koren, SI Borysov, AB Schmid, JF Abisambra, LJ Blair, ... Journal of Neuroscience 30 (2), 591-599, 2010 | 228 | 2010 |
| Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden JC O'Leary, Q Li, P Marinec, LJ Blair, EE Congdon, AG Johnson, ... Molecular Neurodegeneration 5 (1), 1-11, 2010 | 201 | 2010 |
| Heat shock protein 90 inhibitors in the treatment of cancer: current status and future directions K Jhaveri, SO Ochiana, MPS Dunphy, JF Gerecitano, AD Corben, RI Peter, ... Expert opinion on investigational drugs 23 (5), 611-628, 2014 | 185 | 2014 |
| Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice L Lebson, K Nash, S Kamath, D Herber, N Carty, DC Lee, Q Li, ... Journal of Neuroscience 30 (29), 9651-9658, 2010 | 146 | 2010 |
| Chaperone signalling complexes in Alzheimer's disease J Koren III, UK Jinwal, DC Lee, JR Jones, CL Shults, AG Johnson, ... Journal of cellular and molecular medicine 13 (4), 619-630, 2009 | 144 | 2009 |
| Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice JF Abisambra, LJ Blair, SE Hill, JR Jones, C Kraft, J Rogers, J Koren, ... Journal of Neuroscience 30 (46), 15374-15382, 2010 | 133 | 2010 |
| Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau J Abisambra, UK Jinwal, Y Miyata, J Rogers, L Blair, X Li, SP Seguin, ... Biological psychiatry 74 (5), 367-374, 2013 | 125 | 2013 |
| Hsp90 and FKBP51: complex regulators of psychiatric diseases M Criado-Marrero, T Rein, EB Binder, JT Porter, J Koren III, LJ Blair Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 120 | 2018 |
| Hsp90 activator Aha1 drives production of pathological tau aggregates LB Shelton, JD Baker, D Zheng, LE Sullivan, PK Solanki, JM Webster, ... Proceedings of the National Academy of Sciences 114 (36), 9707-9712, 2017 | 106 | 2017 |
| Hsc70 rapidly engages tau after microtubule destabilization UK Jinwal, JC O'Leary, SI Borysov, JR Jones, Q Li, J Koren, JF Abisambra, ... Journal of biological chemistry 285 (22), 16798-16805, 2010 | 102 | 2010 |
| Facilitating Akt clearance via manipulation of Hsp70 activity and levels J Koren, UK Jinwal, Y Jin, J O’Leary, JR Jones, AG Johnson, LJ Blair, ... Journal of biological chemistry 285 (4), 2498-2505, 2010 | 97 | 2010 |
| Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy C Dickey, C Kraft, U Jinwal, J Koren, A Johnson, L Anderson, L Lebson, ... The American journal of pathology 174 (1), 228-238, 2009 | 86 | 2009 |
| The Diarylheptanoid (+)-aR,11S-Myricanol and Two Flavones from Bayberry (Myrica cerifera) Destabilize the Microtubule-Associated Protein Tau JR Jones, MD Lebar, UK Jinwal, JF Abisambra, J Koren III, L Blair, ... Journal of natural products 74 (1), 38-44, 2011 | 82 | 2011 |
| The Hsp90 kinase co-chaperone Cdc37 regulates tau stability and phosphorylation dynamics UK Jinwal, JH Trotter, JF Abisambra, J Koren, LY Lawson, GD Vestal, ... Journal of Biological Chemistry 286 (19), 16976-16983, 2011 | 79 | 2011 |
| Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism A Suntharalingam, JF Abisambra, JC O'Leary, J Koren, B Zhang, MK Joe, ... Journal of Biological Chemistry 287 (48), 40661-40669, 2012 | 77 | 2012 |
| Molecular chaperones and regulation of tau quality control: strategies for drug discovery in tauopathies Y Miyata, J Koren, J Kiray, CA Dickey, JE Gestwicki Future medicinal chemistry 3 (12), 1523-1537, 2011 | 73 | 2011 |
| HSP90 supports tumor growth and angiogenesis through PRKD2 protein stabilization N Azoitei, K Diepold, C Brunner, A Rouhi, F Genze, A Becher, H Kestler, ... Cancer research 74 (23), 7125-7136, 2014 | 71 | 2014 |
Chad DickeyUniversity of South Florida Byrd Alzheimer's InstituteVerifierad e-postadress på health.usf.edu
