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Mike Sutcliffe
Mike Sutcliffe
Interim Head of School of Engineering, Arden University
Verified email at arden.ac.uk
Title
Cited by
Cited by
Year
An automated approach for clustering an ensemble of NMR-derived protein structures into conformationally related subfamilies
LA Kelley, SP Gardner, MJ Sutcliffe
Protein Engineering, Design and Selection 9 (11), 1063-1065, 1996
5721996
Knowledge based modelling of homologous proteins, Part I: Three-dimensional frameworks derived from the simultaneous superposition of multiple structures
MJ Sutcliffe, I Haneef, D Carney, TL Blundell
Protein Engineering, Design and Selection 1 (5), 377-384, 1987
5481987
Crystal structure of a PDZ domain
JHM Cabral, C Petosa, MJ Sutcliffe, S Raza, O Byron, F Poy, SM Marfatia, ...
Nature 382 (6592), 649-652, 1996
4381996
Atomic description of an enzyme reaction dominated by proton tunneling
L Masgrau, A Roujeinikova, LO Johannissen, P Hothi, J Basran, ...
Science 312 (5771), 237-241, 2006
3952006
Knowledge‐based protein modelling and design
T Blundell, D Carney, S Gardner, F Hayes, B Howlin, T Hubbard, ...
European Journal of Biochemistry 172 (3), 513-520, 1988
3481988
Knowledge based modelling of homologous proteins, Part II: Rules for the conformations of substituted sidechains
MJ Sutcliffe, FRF Hayes, TL Blundell
Protein Engineering, Design and Selection 1 (5), 385-392, 1987
3321987
Enzymatic H-transfer requires vibration-driven extreme tunneling
J Basran, MJ Sutcliffe, NS Scrutton
Biochemistry 38 (10), 3218-3222, 1999
2871999
Cytochrome P450 6M2 from the malaria vector Anopheles gambiae metabolizes pyrethroids: Sequential metabolism of deltamethrin revealed
BJ Stevenson, J Bibby, P Pignatelli, S Muangnoicharoen, PM O’Neill, ...
Insect biochemistry and molecular biology 41 (7), 492-502, 2011
2692011
A single aspartate residue is involved in both intrinsic gating and blockage by Mg2+ of the inward rectifier, IRK1.
PR Stanfield, NW Davies, PA Shelton, MJ Sutcliffe, IA Khan, WJ Brammar, ...
The Journal of physiology 478 (1), 1-6, 1994
2451994
Ligand binding to integrin αIIbβ3 is dependent on a MIDAS-like domain in the β3 subunit
EC Tozer, RC Liddington, MJ Sutcliffe, AH Smeeton, JC Loftus
Journal of Biological Chemistry 271 (36), 21978-21984, 1996
2211996
A model for human cytochrome P450 2D6 based on homology modeling and NMR studies of substrate binding
S Modi, MJ Paine, MJ Sutcliffe, LY Lian, WU Primrose, CR Wolf, ...
Biochemistry 35 (14), 4540-4550, 1996
2211996
A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation
CF Oliver, S Modi, MJ Sutcliffe, WU Primrose, LY Lian, GCK Roberts
Biochemistry 36 (7), 1567-1572, 1997
2031997
TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies
M MacFarlane, SL Kohlhaas, MJ Sutcliffe, MJS Dyer, GM Cohen
Cancer research 65 (24), 11265-11270, 2005
1992005
The catalytic mechanism of cytochrome P450 BM3 involves a 6 Å movement of the bound substrate on reduction
S Modi, MJ Sutcliffe, WU Primrose, LY Lian, GCK Roberts
Nature structural biology 3 (5), 414-417, 1996
1681996
Biodiversity of cytochrome P450 redox systems
KJ McLean, M Sabri, KR Marshall, RJ Lawson, DG Lewis, D Clift, ...
Biochemical Society Transactions 33 (4), 796-801, 2005
1672005
A new conceptual framework for enzyme catalysis: Hydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes
MJ Sutcliffe, NS Scrutton
European Journal of Biochemistry 269 (13), 3096-3102, 2002
1672002
Structure of hen lysozyme in solution
LJ Smith, MJ Sutcliffe, C Redfield, CM Dobson
Journal of molecular biology 229 (4), 930-944, 1993
1591993
Analysis of. vphi. and. chi. 1 torsion angles for hen lysozyme in solution from proton NMR spin-spin coupling constants
LJ Smith, MJ Sutcliffe, C Redfield, CM Dobson
Biochemistry 30 (4), 986-996, 1991
1511991
Drug block of the hERG potassium channel: insight from modeling
PJ Stansfeld, P Gedeck, M Gosling, B Cox, JS Mitcheson, MJ Sutcliffe
Proteins: Structure, Function, and Bioinformatics 68 (2), 568-580, 2007
1422007
[23] Protein-ligand interactions: Exchange processes and determination of ligand conformation and protein-ligand contacts
LY Lian, IL Barsukov, MJ Sutcliffe, KH Sze, GCK Roberts
Methods in enzymology 239, 657-700, 1994
1371994
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