| Extraction, purification and analysis of histones D Shechter, HL Dormann, CD Allis, SB Hake Nature protocols 2 (6), 1445-1457, 2007 | 1103 | 2007 |
| ATR and ATM regulate the timing of DNA replication origin firing D Shechter, V Costanzo, J Gautier Nature cell biology 6 (7), 648-655, 2004 | 471 | 2004 |
| WSTF regulates the H2A. X DNA damage response via a novel tyrosine kinase activity A Xiao, H Li, D Shechter, SH Ahn, LA Fabrizio, H Erdjument-Bromage, ... Nature 457 (7225), 57-62, 2009 | 468 | 2009 |
| The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond N Stopa, JE Krebs, D Shechter Cellular and molecular life sciences 72, 2041-2059, 2015 | 467 | 2015 |
| An ATR-and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication V Costanzo, D Shechter, PJ Lupardus, KA Cimprich, M Gottesman, ... Molecular cell 11 (1), 203-213, 2003 | 453 | 2003 |
| Regulation of DNA replication by ATR: signaling in response to DNA intermediates D Shechter, V Costanzo, J Gautier DNA repair 3 (8-9), 901-908, 2004 | 282 | 2004 |
| Clamp loading, unloading and intrinsic stability of the PCNA, β and gp45 sliding clamps of human, E. coli and T4 replicases N Yao, J Turner, Z Kelman, PT Stukenberg, F Dean, D Shechter, ZQ Pan, ... Genes to Cells 1 (1), 101-113, 1996 | 272 | 1996 |
| A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression H Chen, B Lorton, V Gupta, D Shechter Oncogene 36 (3), 373-386, 2017 | 191 | 2017 |
| The intrinsic DNA helicase activity of Methanobacterium thermoautotrophicum ΔH minichromosome maintenance protein DF Shechter, CY Ying, J Gautier Journal of Biological Chemistry 275 (20), 15049-15059, 2000 | 183 | 2000 |
| Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity MC Ho, C Wilczek, JB Bonanno, L Xing, J Seznec, T Matsui, LG Carter, ... PloS one 8 (2), e57008, 2013 | 164 | 2013 |
| Cellular consequences of arginine methylation BM Lorton, D Shechter Cellular and Molecular Life Sciences 76, 2933-2956, 2019 | 115 | 2019 |
| Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase ES Burgos, C Wilczek, T Onikubo, JB Bonanno, J Jansong, U Reimer, ... Journal of Biological Chemistry 290 (15), 9674-9689, 2015 | 93 | 2015 |
| DNA unwinding is an Mcm complex-dependent and ATP hydrolysis-dependent process D Shechter, CY Ying, J Gautier Journal of Biological Chemistry 279 (44), 45586-45593, 2004 | 83 | 2004 |
| Analysis of histones in Xenopus laevis: I. A distinct index of enriched variants and modifications exists in each cell type and is remodeled during developmental transitions D Shechter, JJ Nicklay, RK Chitta, J Shabanowitz, DF Hunt, CD Allis Journal of Biological Chemistry 284 (2), 1064-1074, 2009 | 81 | 2009 |
| ATM and ATR check in on origins: a dynamic model for origin selection and activation D Shechter, J Gautier Cell Cycle 4 (2), 238-240, 2005 | 72 | 2005 |
| Fly fishing for histones: catch and release by histone chaperone intrinsically disordered regions and acidic stretches C Warren, D Shechter Journal of molecular biology 429 (16), 2401-2426, 2017 | 69 | 2017 |
| Protein arginine methyltransferase Prmt5-Mep50 methylates histones H2A and H4 and the histone chaperone nucleoplasmin in Xenopus laevis eggs C Wilczek, R Chitta, E Woo, J Shabanowitz, BT Chait, DF Hunt, ... Journal of Biological Chemistry 286 (49), 42221-42231, 2011 | 66 | 2011 |
| A distinct H2A. X isoform is enriched in Xenopus laevis eggs and early embryos and is phosphorylated in the absence of a checkpoint D Shechter, RK Chitta, A Xiao, J Shabanowitz, DF Hunt, CD Allis Proceedings of the National Academy of Sciences 106 (3), 749-754, 2009 | 59 | 2009 |
| Developmentally regulated post-translational modification of nucleoplasmin controls histone sequestration and deposition T Onikubo, JJ Nicklay, L Xing, C Warren, B Anson, WL Wang, ES Burgos, ... Cell reports 10 (10), 1735-1748, 2015 | 52 | 2015 |
| Analysis of Histones in Xenopus laevis: II. MASS SPECTROMETRY REVEALS AN INDEX OF CELL TYPE-SPECIFIC MODIFICATIONS ON H3 AND H4 JJ Nicklay, D Shechter, RK Chitta, BA Garcia, J Shabanowitz, CD Allis, ... Journal of biological chemistry 284 (2), 1075-1085, 2009 | 52 | 2009 |
Donald F HuntProfessor of Chemistry, University of VirginiaVerified email at virginia.edu
